Cooperative Centers on Human Immunology (CCHI)

Cooperative Centers on Human Immunology (CCHI) 

Established in 2003 by NIAID, the long-term goal of the Cooperative Centers on Human Immunology (CCHI) program is to translate immunology research into clinical applications in humans in the areas of infectious disease and immune-mediated diseases.   


CCHI supports mechanistic and hypothesis-testing studies to discover novel molecules, mechanisms, or regulatory pathways governing function of the human immune system in both healthy and vulnerable populations (i.e., across lifespan, organ/tissue transplant recipients, and pregnant women).

Main Areas of Focus

  • To support research on human immune system regulation and function for the discovery and characterization of new principles of human immunology for the prevention and treatment of infectious and immune-mediated diseases.  
  • To support the development of new technologies to study the human immune system.  
  • To support the stable, flexible, centralized infrastructure needed to promote and coordinate multi-disciplinary research in human immunology. 

Current Centers (FY19-FY23) 

  • Emory University  
  • La Jolla Institute for Immunology  
  • Massachusetts General Hospital  
  • Oklahoma Medical Research Foundation  
  • Rockefeller University  
  • Stanford University  
  • The Jackson Laboratory  
  • University of Alabama at Birmingham  


The program will be renewed in the fiscal year of 2024 (FY24), RFA-AI-22-069 

Contact Information

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