Genomic Centers for Infectious Diseases (GCID) Resources

The GCID use and develop or improve innovative applications of genomic technologies, such as RNA sequencing and metagenomics, and provide rapid and cost-efficient production of high-quality genome sequences of microorganisms, invertebrate vectors of infectious diseases, and hosts and host microbiomes. Multiple strains and isolates of specific microbial species, populations and communities have been and continue to be sequenced.

Services are provided by and program-generated data and software are made available through:

Main Areas of Focus

  • To sequence multiple strains and isolates of specific microbial species, populations and communities.
  • To provide bioinformatics software tools and analyses for studying infectious diseases with the intent to be used by the broader infectious diseases community.
  • To sequence the genomes of microorganisms from the NIAID list of emerging and re-emerging infectious diseases, which includes NIAID Category A-C priority pathogens including influenza, clinical isolates, closely related species and strains, and invertebrate vectors of diseases.

Tools

  • Publicly accessible Websites, databases, and software.
  • Reagents are made available by the NIAID-funded BEI Resources Repository.

Support Services

The GCIDs sequence the genomes of microorganisms from the NIAID list of emerging and re-emerging infectious diseases, which includes NIAID Category A-C priority pathogens including influenza, clinical isolates, closely related species and strains, and invertebrate vectors of diseases.

  • Genomic capabilities include:
    • High-throughput next-generation sequencing
    • Comparative genomic and phylogenomic analysis
    • Genotyping
    • Gene expression
    • Simultaneous processing and analysis of host-pathogen or metagenomic and metatranscriptomic analysis
  • Methods and protocols developed for next-generation sequencing and related genomic technologies.
  • Bioinformatics software tools and analyses for studying infectious diseases with the intent to be used by the broader infectious diseases community.

Standards

  • Methods and protocols for next-generation sequencing and related genomic technologies.

Who Can Use This Resource

  • Investigators in academia, not-for-profit organizations, industry, and government worldwide.

How To Get Started

  • Investigators interested in requesting sequencing, assembly, primary annotation, and analysis of microorganisms, invertebrate vectors of infectious diseases, and hosts and host microbiomes should submit a one page description of the project for consideration to Eun Mi Lee.
  • Please include a justification and relevant background.
  • Priority will be given to projects that fall within the scope of ongoing research within the GCIDs.
Content last reviewed on June 29, 2018