Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP)

The Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP) aims to develop preclinical porcine to nonhuman primate models of islet, kidney, heart, lung, or liver xenotransplantation.

Main Areas of Focus

  • To delineate the cellular and molecular mechanisms of xenograft rejection and the induction of tolerance
  • To develop effective strategies to improve xenograft survival
  • To characterize the physiological compatibility/limitations of xenografts
  • To develop novel and effective strategies for application of xenotransplantation in the clinic
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