The Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP) aims to develop preclinical porcine to nonhuman primate models of islet, kidney, heart, lung, or liver xenotransplantation.
Main Areas of Focus
- To delineate the cellular and molecular mechanisms of xenograft rejection and the induction of tolerance
- To develop effective strategies to improve xenograft survival
- To characterize the physiological compatibility/limitations of xenografts
- To develop novel and effective strategies for application of xenotransplantation in the clinic
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