Inner-City Asthma Consortium (ICAC)

Inner-City Asthma Consortium (ICAC) focuses on understanding how the environment, allergens, and genetics interact with the body’s immune system to cause asthma and aggravate its symptoms.

Main Areas of Focus

  • To understand the underlying mechanisms of candidate therapies
  • To develop and validate biomarkers to measure disease stage, progression, and therapeutic effect of candidate treatments
  • To assess how possible genetic and epigenetic (changes in gene expression or observable trait that are not caused by changes in DNA sequence) factors influence disease development, progression, and severity
  • To define the development and unique mechanisms associated with asthma onset and severity in inner-city children
  • To identify environmental factors associated with inner-city asthma

See ICAC clinical trials that are currently recruiting participants

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