In an effort to support tropical medicine research in endemic international areas and in populations most affected by these diseases, NIAID initiated the Tropical Medicine Research Centers (TMRC) program in 1991.
In 2012, NIAID funded eight Centers to conduct research on the following neglected tropical diseases (NTDs): schistosomiasis, hookworm infection, ascariasis, leishmaniasis, Chagas' disease, lymphatic filariasis, and foodborne trematodiases. In 2017, the TMRC program was renewed and NIAID funded 7 Centers (five new Centers and two renewals), focusing on NTDs such as leishmaniasis, neurocysticercosis, and Chagas' disease.
The TMRC program also supports clinical and field site development. A major outcome of this research program is to build capacity to enable TMRCs to conduct future clinical trials, implement new treatment and prevention strategies, and develop novel vector control strategies.