The Throughput Ranking by Iterative Analysis of Genomic Enrichment (TRIAGE) platform is designed to facilitate prediction, analysis, and hypothesis generation from High-throughput genomic studies such as those done by CRISPR, RNAseq, proteomic, and clinical sequencing studies.
More information about this resource is available at the TRIAGE website
Main Areas of Focus
- To facilitate prediction, analysis, and hypothesis generation from genome-wide perturbation, sequencing, and clinical studies.
- To guide prioritization of candidates for follow up analysis from high-throughput studies.
TRIAGE is best utilized as tool for selecting candidates from high-throughput studies to be further validated by rigorous low throughput follow up studies. TRIAGE integrates analysis from gene to gene predicted interactions and statistical enrichments of known gene sets to correct for the false positive and false negative error rates that are associated with normalization methods that require arbitrary cutoffs. By utilizing data sorted into low, medium and high confidence tiers the TRIAGE platform integrates the experimental readout of the analyzed study with a priori knowledge about biological networks and interactions.
Who Can Use This Resource
TRIAGE is publicly available to users and provides access to only publicly available information.