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- Contact Information
- Animal Capabilities
- Animal Models
- Imaging Capabilities
- Laboratory and Analytical Support
- cGLP or cGMP Capabilities
- Specialized Areas or Major Equipment Available
- Shared Resources Within the Institution
- Guinea pigs
- Gnotobiotic piglets
- Mice: Francisella tularensis (aerosol, intranasal, intradermal); Yersinia pestis (intranasal, sc, aerosol); Bacillus anthracis (aerosol); botulinum toxins (iv); Mycobacterium tuberculosis and M. bovis (aerosol, intranasal)
- Guinea pigs: M. tuberculosis (aerosol)
- Rabbits: B. anthracis (aerosol)
- Rats: F. tularensis (intranasal; Y. pestis (intranasal)
F. tularensis, Y. pestis, B. anthracis, M. tuberculosis, M. bovis, Clostridium botulinum neurotoxins A-G, and EEE.
Xenogen IVIS Spectrum within the ABSL3 vivarium
- Immunology services: Flow cytometer and ELISPOT reader available in the RBL
- Pathology services: Clinical and Anatomical Pathology support available through the Department of Biomedical Sciences on campus. The TCSVM Histology Laboratory is also available.
The supporting BSL2 laboratory has a NanoDrop 2000c spectrophotometer, BioTek Synergy 4 Multidetection Plate Reader, UVP BioDocIt imaging system, CTL ImmunoSpot S5 reader, and an ABI 7500 Fast Real-Time PCR instrument. Also in BSL2 space is a Zeiss LSM700 confocal microscope with live cell imaging capability.
Located within ABSL3 space is an IVIS Spectrum, a BDFortessa flow cytometer (3 lasers, 18 detectors), a Drew Scientific HemaVet950 and an Abraxis VetScan2. Separate aerobiology (CH Technologies nose-only inhalation exposure system in a Baker Class III hood) and insectary suites are located within the ABSL3 vivarium.
A DSI telemetry system for monitoring animals is also available.
Separate Botulinum Neurotoxin Select Agent Facility with both animal and laboratory space, and an isolated BSL3 animal/laboratory space for tularemia-related research; Department of Infectious Disease and Global Health—staff of 50 with technical expertise in animal models for many of the NIAID Priority A, B, and C Pathogens, plus access to equipment within the department.