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The ever-changing “head†of an influenza virus protein has an unexpected Achilles heel, report scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health. The team discovered and characterized the structure of a naturally occurring human antibody that recognizes and disrupts a portion of the hemagglutinin (HA) protein that the virus uses to enter and infect cells.
Last Reviewed: May 16, 2019
Many people with HIV on antiretroviral therapy (ART) have viral genetic material in the cells of their cerebrospinal fluid (CSF), and these individuals are more likely to experience memory and concentration problems, according to new data published online today in the Journal of Clinical Investigation. A study of 69 individuals on long-term ART found that nearly half of the participants had
Published: July 15, 2019
The FDA issued an Emergency Use Authorization to Moderna, Inc. for its COVID-19 vaccine, which was co-developed with scientists at NIH NIAID and Moderna.
Published: December 18, 2020
Jordan Report 2012
https://www.niaid.nih.gov/sites/default/files/jordanreport2012.pdf
Last Reviewed: December 31, 2012
An experimental approach to enhancing a standard cat allergen immunotherapy, often called allergy shots, made it more effective and faster acting, and the benefits persisted for a year after treatment ended.
Published: October 11, 2022
In the 34 years since the first observance of World AIDS Day, transformational progress has been made in the global fight against HIV/AIDS, yet challenges remain. Today, we at the National Institutes of Health reflect on the 40 million lives lost to the disease and renew our commitment to the research necessary to end the global pandemic. Innovative research led to the highly effective HIV
Published: December 1, 2022
A NIH study to determine the rate of novel coronavirus infection in children and family members in the United States has begun enrolling participants.
Published: May 4, 2020
The Jordan Report: Accelerated Development of Vaccines 2007
https://www.niaid.nih.gov/sites/default/files/jordan2007.pdf
Last Reviewed: August 6, 2019
Jordan Report 20th Anniversary: Accelerated Development of Vaccines 2002
https://www.niaid.nih.gov/sites/default/files/jordan20_2002.pdf
Last Reviewed: December 31, 2002
Expert Articles, NIAID Jordan Report 2012
https://www.niaid.nih.gov/sites/default/files/jordan2012_expertarticles.pdf
Last Reviewed: December 31, 2012
H. Clifford Lane, M.D., is the Deputy Director of Clinical Research and Special Projects, the Director of the Division of Clinical Research Clinical Director of NIAID, and the Chief of the Clinical and Molecular Retrovirology Section. In the laboratory, Dr. Lane’s early work involved studies aimed at dissecting the normal immunoregulatory mechanisms that control the human immune response to specific antigen challenges. When the AIDS epidemic emerged, he became one of the first investigators to study immunopathogenic mechanisms of HIV disease, ultimately making seminal observations that helped establish the field of HIV immunopathogenesis.
Last Reviewed: April 18, 2024
Ethical Considerations for Zika Virus Human Challenge Trials
https://www.niaid.nih.gov/sites/default/files/EthicsZikaHumanChallengeStudiesReport2017.pdf
Last Reviewed: November 26, 2019
Since 1988, World AIDS Day has been an annual call to end the HIV/AIDS pandemic as we remember the many who lost their lives to the disease. Considerable progress has been made since the first World AIDS Day; however, far too many people continue to acquire HIV and die from its related illnesses.
Published: December 1, 2021
Today marks the 140th anniversary of the announcement by Dr. Robert Koch that tuberculosis (TB) is caused by the bacterium Mycobacterium tuberculosis. World TB Day is a reminder that this ancient disease remains a relentless killer. The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, affirms its commitment to the 2022 World TB Day theme
Published: March 24, 2022
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), reaffirms our commitment to developing safe and effective medical tools against malaria, and, in the words of this year’s World Malaria Day theme, “Harnessing innovation to reducing the malaria disease burden and saving lives.â€
Published: April 25, 2022
The Division of Intramural Research (DIR), a component of the National Institute of Allergy and Infectious Diseases, has long been at the forefront of research on immunologic, allergic, and infectious diseases. For more than 60 years, DIR scientists have discovered new pathogens, deciphered normal immune system function, identified aberrations underlying immunological diseases, and developed FDA
Last Reviewed: June 6, 2024
The 206 th meeting of the National Advisory Allergy and Infectious Diseases Council (NAAIDC) convened virtually at 10:30 a.m. on Tuesday, January 30, 2024. Dr. Jeanne Marrazzo, Director, National Institute of Allergy and Infectious Diseases (NIAID) presided as chair. In accordance with the provisions of Public Law 92-463, the meeting was open to the public from 10:30 a.m. to 11:45 a.m. and from 1
Last Reviewed: May 21, 2024