Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum. It is transmitted from person to person via direct contact with a syphilitic sore, known as a chancre. These sores can be found on the genitals, vagina, anus, rectum, lips and mouth. Pregnant women can transmit the disease to their unborn child. Syphilis can cause long-term health complications if left untreated.
Why Is the Study of Syphilis a Priority for NIAID?
An ancient disease, syphilis is still of major importance today. The Centers for Disease Control and Prevention estimates that each year 55,400 people in the United States get new syphilis infections. During 2012, there were 49,903 reported new cases. In addition, HIV infection and syphilis are linked. Syphilis increases the risk of transmitting as well as getting infected with HIV.
How Is NIAID Addressing This Critical Topic?
Developing better ways to diagnose and treat syphilis is an important research goal of scientists supported by NIAID.
Scientists are developing new tests that may provide better ways to diagnose syphilis and define the stage of infection. Efforts to develop a diagnostic test that would not require a blood sample are a high priority. For example, researchers are evaluating tests using saliva and urine to see whether they would work as well as blood tests. Researchers are also trying to develop other diagnostic tests for detecting infection in babies.