The Multicenter AIDS Cohort Study (MACS) is an ongoing prospective study of the natural and treated histories of HIV-1 infection in homosexual and bisexual men conducted by sites located in Baltimore, Chicago, Pittsburgh and Los Angeles. Biological and behavioral data are collected every six months from study participants.
Main Areas of Focus
- To address the key questions facing HIV research today, including the effects of HIV, cART, and age on HIV-induced inflammation and immune dysfunction and on non-AIDS-defining outcomes including cancer, cardiovascular, liver, metabolic, neurologic, psychologic, and renal disease
- To collect specimens for helping to understand the pathogenesis of HIV-1 infection and the development of disease in HIV-infected people