Multicenter AIDS Cohort Study (MACS)

The Multicenter AIDS Cohort Study (MACS) is an ongoing prospective study of the natural and treated histories of HIV-1 infection in homosexual and bisexual men conducted by sites located in Baltimore, Chicago, Pittsburgh and Los Angeles. Biological and behavioral data are collected every six months from study participants.

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Main Areas of Focus

  • To address the key questions facing HIV research today, including the effects of HIV, cART, and age on HIV-induced inflammation and immune dysfunction and on non-AIDS-defining outcomes including cancer, cardiovascular, liver, metabolic, neurologic, psychologic, and renal disease
  • To collect specimens for helping to understand the pathogenesis of HIV-1 infection and the development of disease in HIV-infected people
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