Papillomavirus Episteme (PaVE)

The PapillomaVirus Episteme (PaVE) provides highly organized and curated papillomavirus genomics information and tools to the scientific community for research on the Papillomaviridae family of viruses. The PaVE consists of a database and web applications that support the storage, annotation, analysis, and exchange of information. To the extent possible, the PaVE adopts an open source software approach and emphasizes integration and reuse of existing tools.

More information about this resource is available at Papillomavirus Episteme (PaVE)

Main Areas of Focus

To provide core components needed to accelerate scientific progress and ultimately our understanding, detection, diagnosis, and treatment of diseases caused by papillomaviruses


  • Database and web applications that support the storage, annotation, analysis, and exchange of information
  • Analysis tools include:
    • Multiple Sequence Alignment
    • Protein Structure Viewer
    • Pavic L1 Taxonomy Tool
  • 360 annotated papillomavirus genomes (including 20 Non-reference genomes), 3688 genes and regions, 3328 protein sequences, and 59 protein structures, which users can explore, analyze or download
  • LANL Human Papillomaviruses Database archive for years 1994 to 1997
  • Graphic visualization of sequence features using a novel “locus view” (GenBank, FASTA, and EMBL formats are also available)
  • Precise BLAST results against the papillomavirus-specific PaVE databases, including all Papillomavirus nucleotide and peptide sequences from GenBank
  • Dynamic keyword search results and filter options that are automatically updated as you apply filters for partial versus complete genomes, year submitted, country of origin, molecule, annotation features, taxonomy, and more
  • Easy-to-browse features such as BLAST alignment roll-ups and drop-down menus



Collaboration Opportunities

Researchers are invited to add new PV types to the PaVE taxonomy

Who Can Use This Resource

Available for public use.

Research Publication

Contact Information

Alison McBride, Ph.D.