Systems Biology Consortium for Infectious Diseases Lecture Series and Meetings

The NIAID/DMID Systems Biology Consortium for Infectious Diseases hosts a webinar series to share the expertise, technological advances, and scientific breakthroughs at each of the centers, and serves as a platform to foster collaboration and knowledge sharing. This lecture series includes members of the NIAID/DMID Systems Biology Consortium and other invited scientists. Lectures are given by participating or invited scientists, ranging from senior investigators to graduate student researchers.

Previous Webinars

2022

An integrated cell atlas of the human lung in health and disease
Dr. Alexander Misharin, Northwestern University
Successful Clinical Response In Pneumonia Therapy (SCRIPT) Systems Biology

2021

The developing adaptive immune response to Lassa Virus infection
Dr. Bryan Briney, Scripps Research Institute
Consortium for Viral Systems Biology (CViSB)

The host autophagy receptor TAX1BP1 is required for Mycobacterium tuberculosis virulence
Dr. Jon Budzik
HPMI: Host Pathogen Mapping Initiative, University of California San Francisco

Beyond Spike: applying systems biology to understand SARS-CoV-2 variants of concern adaptations
Dr. Lorena Zuliani-Alvarez
HPMI: Host Pathogen Mapping Initiative, University of California San Francisco

Data-driven Inference of Drug Synergy
Dr. Shuyi Ma, University of Washington
OMICS for TB: Response to Infection and Treatment

From Detection to Predicting Infectious Disease and Antibiotic Resistance Outcomes
Dr. Tim van Opijnen, Boston College
Predicting the Emergence of Antibiotic Resistance through Multi-Omics Approaches and Immune System Surveillance 

Pan-Microbiome Profiling Identifies Enterotype-Specific Taxa and Metagenomic Functions for Infectious Diarrheal Disease Susceptibility and Classification
Drs. Tor Savidge and Joseph Sorg (Baylor College of Medicine and Texas A&M University)
Decoding Antibiotic-Induced Susceptibility to Clostridium difficile Infection

Systems Immunobiology of Persistent MRSA Bacteremia
Drs. Michael Yeaman, Elaine Reed, Aaron Meyer, Richard Ahn, and Vance Folwer (University of California Los Angeles and Duke University) 
Systems Immunolobiology of Antibiotic-Persistent MRSA Infection

Progress with iModulons and Comparative Pangenomics
Dr. Bernhard Palsson, Dr. Anand Sastry, and Jason Hyun (University of California San Diego) Systems Biology Approach to Redefine Susceptibility Testing and Treatment of MDR Pathogens in the Context of Host Immunity

The Gut Microbiota Protects Patients from Antimicrobial-Resistant Infection 
Drs. Eric Pamer, João Xavier, Justin Cross, and Andy Goodman (Memorial Sloan Kettering Cancer Center and University of Chicago) 
Systems Biology of Microbiome-Mediated Resilience to Antibiotic Resistant Pathogens

Emerging Variants of SARS-CoV-2
Dr. Kristian Andersen, Scripps Research Institute
Consortium for Viral Systems Biology (CViSB)

2020

Distribution of Lassa Virus in the Natural Host
Allison Smither, Tulane University 
Consortium for Viral Systems Biology (CViSB)

Mouse models to understand the systems biology of C. difficile infection
Vincent Young, M.D., Ph.D and Lisa Abernathy-Close, University of Michigan
Systems Biology of Clostridium difficile Infection

A SARS-CoV-2 Protein Interaction Map Revels Targets for Drug Repurposing
Dr. David Gordon, University of California San Francisco
HPMI: Host Pathogen Mapping Initiative

Next Gen Data Analytics for AMR and Virulence 
Dr. Berhnard Palsson, Dr. Anand Sastry, Dr. Jonathan Monk, and Erol Kavvas (University of California San Diego) 
Systems Biology Approach to Redefine Susceptibility Testing and Treatment of MDR Pathogens in the Context of Host Immunity

A Blood RNA Signature in Ultra-Low Dose Infected Mice Predicts Human Tuberculosis Outcomes 
Dr. Courtney Plumlee (Seattle Children’s) 
OMICS for TB: Response to Infection and Treatment

Using Advanced Microscopy and Analytic Tools to Identify Factors that Restrict T Cell Function within the TB Granuloma 
Dr. Benjamin Gern (Seattle Children’s) 
OMICS for TB: Response to Infection and Treatment

Global Identification of RNA-Protein Interactions during Mtb Infection
Dr. Haridha Shivram, University of California at Berkeley
HPMI: Host Pathogen Mapping Initiative

Autophagy and Mycobacterium Tuberculosis
Dr. Guillaume Golovkine, University of California at Berkeley
HPMI: Host Pathogen Mapping Initiative

Functional Omics to Define Dysbiosis and Disease Progression in C. difficile Infection
Dr. Qinglong Wu, Baylor College of Medicine
Decoding Antibiotic-Induced Susceptibility to Clostridium difficile Infection

The Protein Interaction Landscape of Influenza A Viruses
Kelsey Haas, University of California San Francisco
FluOMICS, The Next Generation

Genetic parallelism in the evolution of aminoglycoside resistance across species, environments, and infections: toward new predictive targets
Dr. Vaughn Cooper, University of Pittsburg
Predicting the Emergence of Antibiotic Resistance through Multi-Omics Approaches and Immune System Surveillance  

Linking evolved drug resistance during Acinetobacter baumannii pneumonia in the mouse to allele variants in the clinic
Dr. Ralph Isberg, Tufts University
Predicting the Emergence of Antibiotic Resistance through Multi-Omics Approaches and Immune System Surveillance  

2019

DNA Methylation Signatures Associated with Antibiotic-Persistent MRSA Bacteremia
Dr. Elaine Reed, Los Angeles Biomedical Institute at Harbor
Systems Immunolobiology of Antibiotic-Persistent MRSA Infection

Temporospatial Evolution and Durability of Cellular Immune Memory During MRSA Infection
Dr. Liana Chan, Los Angeles Biomedical Institute at Harbor
Systems Immunolobiology of Antibiotic-Persistent MRSA Infection

Transcriptomic profiling of FACS sorted human alveolar macrophages to identify predictors of Successful Clinical Response in Pneumonia Therapy
Dr. Alexander Misharin, Northwestern University
Successful Clinical Response In Pneumonia Therapy (SCRIPT) Systems Biology

2018

Impact of commensal microbiota changes on fecal metabolites and antibiotic-resistant pathogens
Drs. Eric Pamer and Justin Cross, Sloan Kettering Institute for Cancer Research
Systems Biology of Microbiome-Mediated Resilience to Antibiotic Resistant Pathogens

Intra-specific competition for co-germinants mediates protection from lethal C. difficile infection
Dr. Vincent Young, University of Michigan
Systems Biology of Clostridium difficile Infection

Predicting the emergence of antibiotic resistance through multi-omics approaches and immune system-surveillance
Dr. Jason Rosch, St. Jude Children’s Research Hospital
Predicting the Emergence of Antibiotic Resistance through Multi-Omics Approaches and Immune System Surveillance

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