NIAID Site Search

The ever-changing ���head��� of an influenza virus protein has an unexpected Achilles heel, report scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health. The team discovered and characterized the structure of a naturally occurring human antibody that recognizes and disrupts a portion of the hemagglutinin (HA) protein that the virus uses to enter and infect cells.

Last Reviewed: May 16, 2019

NIAID scientists determined the high-resolution 3D structure of an Epstein-Barr virus (EBV) surface protein in complex with its receptor, revealing a key site of vulnerability that could lead to much-needed interventions against this common human pathogen.

Published: March 4, 2025

For decades, scientists have wondered how different strains of prions can propagate when they do not carry their own genes with them as they move from host to host. A new study from NIAID researchers and colleagues reveals how differences in the folding of the primary protein of prions (PrP) can help determine the distinct characteristics of prion strains.

Published: July 13, 2022

A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood. This immune response contrasts with that typically seen in adults with SARS-CoV-2 infection.

Published: October 13, 2023

Fatal familial insomnia (FFI) is a little-known yet horrific disease in which people die from lack of sleep. In a new study, NIAID scientists developed a cerebral organoid model to study the exact protein mutation that causes FFI.

Published: January 19, 2023

As global temperatures rise, it has become more urgent to understand the interactions between climate, mosquitoes, and the pathogens mosquitoes transmit to humans. NIAID Now spoke to Luis Chaves, Ph.D., a 2023 Scholar with the National Institutes of Health (NIH) Climate Change and Health Initiative, about his work about the impacts of environmental change on the ecology of insect vectors and the diseases they transmit.

Published: August 18, 2023

Sample grant application from Stephen Dewhurst, Ph.D., for exploratory with possible transition to expanded development grant (R21/R33).

Last Reviewed: April 21, 2025

Lenette Lu, M.D., Ph.D., of the Massachusetts General Hospital K08 sample application

Last Reviewed: March 31, 2025

Tuan Manh Tran, M.D., Ph.D., of the Indiana University-Purdue University at Indianapolis K08 sample application

Last Reviewed: March 31, 2025

Stephen Dewhurst, Ph.D., of the University of Rochester, R21/R33 sample application

Last Reviewed: March 31, 2025

Nico Contreras, Ph.D., of University of Arizona, F31 sample application

Last Reviewed: March 31, 2025

Lilliam Ambroggio, Ph.D., of the Cincinnati Children’s Hospital Medical Center K01 sample application

Last Reviewed: March 31, 2025

Sample application from Emily Troemel, Ph.D., for NIH standard independent research project grant (R01).

Last Reviewed: October 11, 2024

Immunology Interest Group (IIG) Newsletter November 2024

Last Reviewed: December 4, 2024

Sample application from David Al-Adra MD, Ph.D., for NIH standard independent research project grant (K08).

Last Reviewed: September 13, 2024

NIAID-supported researchers explore the genetic underpinnings of how malaria parasites evolve drug resistance.

Last Reviewed: December 5, 2024

An ongoing NIAID-supported trial is testing whether rapid tests for antibiotic susceptibility can improve patient outcomes.

Published: October 25, 2024

National Institutes of Health // Food and Drug Administration // Immunology Interest Group

Last Reviewed: April 16, 2024

The immune system is a network of cells, tissues, and organs that work together to protect the body from infection. Although scientists have learned much about the immune system, they continue to study how the body targets invading microbes, infected cells, and tumors while ignoring healthy tissues.

Last Reviewed: July 11, 2016

Immunology Interest Group (IIG) Newsletter May 2024

Last Reviewed: October 2, 2024

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus. The research was led by Jeffrey I. Cohen, M.D., and colleagues from NIAID.

Published: March 12, 2024

The NIAID Centers for HIV Structural Biology captured in unprecedented detail the 3-D structures of HIV components bound to human cellular components.

Last Reviewed: March 21, 2025

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1). Researchers identified the treatment based on their discovery that the syndrome is linked to elevated levels of interferon-gamma (IFN-gamma), a protein involved in immune system responses, providing new insights into

Published: May 30, 2024

Explanation of two strategies under study for HIV viral eradication from NIAID.

Last Reviewed: March 26, 2019

Information about NIAID-supported research on asthma risk factors and prevention.

Last Reviewed: April 5, 2018