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Nico Contreras, Ph.D., of University of Arizona, F31 sample application
https://www.niaid.nih.gov/sites/default/files/f31-sample-application_nico_contreras.pdf
Last Reviewed: March 31, 2025
The Vector Molecular Biology Section focuses on understanding how molecules from arthropod vectors are critical for the success of pathogen transmission and translating this knowledge into disease control opportunities.
Last Reviewed: September 27, 2022
In the BPARS, we apply a systems biology approach to understand selection dynamics and host-pathogen interactions in the context of defined genetic immunodeficiency diseases. This approach integrates genomics, transcriptomics (RNA-seq), and metabolomic methods to identify and characterize specializations that occur during within-host adaptation.
Last Reviewed: January 21, 2025
AADCRC investigators conduct clinical research studies on asthma and allergic diseases, as well as respiratory infections.
Last Reviewed: May 13, 2025
An overview of the NIAID Laboratory of Immunoregulation including major areas of research.
Last Reviewed: December 4, 2024
Dr. Ghosh’s research within the Bacterial Pathogenesis and Antimicrobial Resistance Unit (BPARU) focuses on the mechanisms of bacterial pathoadaptation that occurs in the context of persistent infection in the immunocompromised host.
Last Reviewed: February 21, 2025
National Institutes of Health scientists and their collaborators have identified an internal communication network in mammals that may regulate tissue repair and inflammation, providing new insights on how diseases such as obesity and inflammatory skin disorders develop. The new research is published in Cell. The billions of organisms living on body surfaces such as the skin of mammals
Published: June 23, 2021
NIAID scientists developed tools to study evolution in enteroviruses—a virus group responsible for polio; hand, foot & mouth disease (HFMD); acute flaccid myelitis (AFM) & other diseases. Their findings may reveal pathways of viral evolution.
Published: December 10, 2024
Sample Summary Statement (R01): Jiang Mengxi
https://www.niaid.nih.gov/sites/default/files/R01_Jiang_Sample_Summary_Statement.pdf
Last Reviewed: January 25, 2023
Sample Application (STTR Phase I / R41): Fong
https://www.niaid.nih.gov/sites/default/files/1r41ai10801601_fong_0.pdf
Last Reviewed: November 29, 2022
Interactions between intracellular bacteria and their hosts in Wolbachia-host symbiotic systems Host-parasite interactions in filarial worm infections Study of arbovirus transmission using vector (mosquito) cells Role of microRNA in prokaryotic-eukaryotic cellular interactions
Last Reviewed: July 6, 2020
Sanjay Desai, M.D., Ph.D. is Chief of the Apicomplexan Molecular Physiology Section at NIAID. We are interested in how malaria parasites acquire nutrients and other essential solutes from the human bloodstream. Our studies have identified two unusual ion channels that play a central role in trafficking solutes between serum and parasite compartments. One of these channels, the plasmodial surface anion channel (PSAC), is exposed on the infected erythrocyte surface and is generally recognized as an important drug target.
Last Reviewed: June 23, 2022
Apply for funding to conduct innovative basic, translational, and clinical research to identify and address epigenetic treatment strategies for achieving hepatitis B virus (HBV) cure in people living with HIV.
Published: July 17, 2024
Report of the Advisory Committee on Research on Women’s Health: Fiscal Years 2019–2020
https://www.niaid.nih.gov/sites/default/files/ORWH-Biennial-Report2019-20.pdf
Last Reviewed: March 8, 2022
Molecular and virological investigation of HIV-1 and HIV-2 and their interactions with host factors.
Last Reviewed: September 21, 2022
Sample Application Fong Full
https://www.niaid.nih.gov/sites/default/files/1r41ai10801601_fong.pdf
Last Reviewed: October 27, 2016
We study how Salmonella Typhimurium interacts with mammalian host cells and the roles these interactions play in pathogenesis.
Last Reviewed: September 28, 2022
Jordan Report 20th Anniversary: Accelerated Development of Vaccines 2002
https://www.niaid.nih.gov/sites/default/files/jordan20_2002.pdf
Last Reviewed: December 31, 2002
Iain Fraser, Ph.D., is the Chief of the Signaling Systems Section. Our research program is focused on the design, implementation, and interpretation of screening efforts to identify and determine the interactions among the components in PRR signaling networks. Our goal is to obtain a better understanding of how PRR signaling pathways control the macrophage inflammatory state, and ultimately to develop strategies to regulate these responses in human inflammatory diseases.
Last Reviewed: September 6, 2022
Current investigators in the NIAID Malaria Research Program
Last Reviewed: February 17, 2022
In recognition of World Mosquito Day on Saturday, Aug. 20, NIAID interviewed grantee Courtney Murdock, Ph.D., of Cornell University to learn more about her team’s research on the relationship between the environment and mosquito-borne diseases. Read how monitoring temperature, humidity – and the need for more data – will affect whether scientists can make a significant public health impact for diseases like malaria, dengue and Zika.
Published: August 19, 2022
Olivia Steele-Mortimer, Ph.D., is Deputy Chief of the Laboratory of Bacteriology and Chief of the Salmonella-Host Cell Interactions Section. Salmonella enterica serovar Typhimurium (S. Typhimurium) is a common cause of gastroenteritis in humans. Our group studies how S. Typhimurium interacts with mammalian cells.
Last Reviewed: July 12, 2022
Concepts represent early planning stages for program announcements, requests for applications, notices of special interest, or solicitations for Council’s input. If NIAID publishes an initiative from one of these concepts, we link to it below. To find initiatives, go to Opportunities & Announcements. Note: Council approval does not guarantee that a concept will become an initiative. Table of
Last Reviewed: February 27, 2025
Regulation of immune cell migration by chemokines in infection and inflammation Mechanisms of immune evasion deployed by herpesviruses Chemokine interactions with membrane phospholipids Regulation of phagocyte recruitment for apoptotic cell clearance by phospholipid-binding chemokines Antimicrobial activity of phospholipid-binding chemokines
Last Reviewed: March 7, 2024
Kim Green, Ph.D., is the Chief of the Caliciviruses Section. One of the major specific areas of research in our laboratory is to develop experimental systems in which to study norovirus replication and immunity.
Last Reviewed: August 10, 2022