Day 2 will include sessions "Navigating Risk in Sharing Cancer Data" and "Sharing difficult-to-share data" in addition to lightning talks and a poster session. Virtual option available. Register on linked website.

Day 1 will include a panel about data sharing and reuse for cancer and sessions "Cancer Data in Action" and "Data Citation and Reuse Metrics."  Virtual option available. Register on linked website.

This study reanalyzed CPTAC colorectal cancer proteomics data using a custom metaproteomics pipeline to identify microbial species and proteins differentially abundant in tumor and normal tissues. It shows that microbial features, particularly from multiplexed data, can support tumor classification and may complement human biomarkers in colorectal cancer research.

The authors developed a statistical framework called spectral network QTL (snQTL) to identify genetic loci that influence gene co-expression networks using spectral tensor decomposition. Applying this method to three-spined stickleback data, they identified genetic regions that affect global co-expression patterns, revealing associations that would be missed by traditional eQTL methods and offering new insights into complex genotype and phenotype relationships.

This article describes glycosyrin, an iminosugar produced by Pseudomonas syringae that inhibits plant β-galactosidases to suppress immune responses. The authors uncovered its structure, biosynthetic pathway, and impact on host glycobiology, highlighting its role as a conserved bacterial virulence factor.

This paper describes EcoWeaver, a new tool for quantifying the degree of shared evolution between genes with the goal of predicting protein function using genomic sequences. The tool combines and builds upon existing coevolutionary analysis approaches to enable use with large data sets and is available for use in the SynExtend R package.

Using multi-omics analysis, the authors show that viral infection push dendritic cell progenitors away from Plasmacytoid Dendritic cell development and this seems to be influenced by Glucocorticoids. Virally infected mice lacking adrenal glands had significantly lower levels of Plasmacytoid Dendritic cells than did infected mice with adrenal glands and the corresponding glucocorticoids.

The authors examined the role of the Translocation and Assembly Module (TAM) subunit, TamL, in Bacteroidetes species. TamL, along with interacting subunit TamB, are found to be essential in two species, including a human pathogen responsible for infections after being bitten or licked by a dog or cat (Capnocytophaga canimorsus).

To better understand and design viral vaccines, it is critical to systematically collect, annotate, and analyse various viral vaccines and identify enriched patterns from these viral vaccines. Authors systematically collected experimentally verified viral vaccines from the literature, manually annotated, and stored the information in the VIOLIN vaccine database. Enriched patterns were identified from systematical analysis of the viral vaccines and vaccine antigens.