Synthetic Tetracyclines To Combat Bacterial Infections

Tetracyclines are broad-spectrum antibiotics used to treat bacterial infections, but many bacteria are developing resistance to treatment. NIAID is supporting the development of novel tetracyclines that are not subject to existing tetracycline resistance mechanisms and therefore represent important new tools for the treatment of multidrug-resistant (MDR) bacterial infections.

National and Regional Biocontainment Research Facilities

The National Biocontainment Laboratories (NBLs) and Regional Biocontainment Laboratories (RBLs) provide BSL4/3/2 and BSL3/2 biocontainment facilities, respectively, for research on biodefense and emerging infectious disease agents.  

Diagnostics Development Services

NIAID’s Diagnostics Development Services program offers reagents, platform testing, and planning and design support to accelerate product development of in vitro diagnostics (IVD) for infectious diseases, from research feasibility through clinical validation.

Derron A. Alves, D.V.M., Diplomate ACVP

Specialty(s): Infectious Disease

Education:

D.V.M., North Carolina State University College of Veterinary Medicine

B.S., Tuskegee University

Image of Derron A. Alves, D.V.M., Diplomate ACVP

José Ribeiro, M.D., Ph.D.

Education:

M.D., State University of Rio de Janeiro

Ph.D., Federal University of Rio de Janeiro

Languages Spoken: Portuguese
José Ribeiro, M.D., Ph.D.

Michael P. O'Connell, Ph.D.

Education:

Ph.D., Cell and Molecular Biology (Developmental Origins of Health and Disease), 2006
M.Sc., Biochemical Pharmacology, 2003
B.Sc., Sport and Health Sciences, minor in Psychology, 2001

Michael O'Connell, Ph.D.

$3M NIH Grant Supports Albany Med Research on Vaccine for Plague

Bioinformatics Resource Centers (BRCs) for Infectious Diseases

The NIAID-funded Bioinformatics Resource Centers provide data-driven, production-level, sustainable computational platforms to enable sharing and access to data, portable computational tools, and standards that support interoperability for the infectious diseases research community.

Laboratory of Neurological Infections and Immunity

Sonja M. Best, Ph.D., Chief

The Laboratory of Neurological Infections and Immunity (LNII) studies persistent active or latent viral or prion disease infections. Investigators place particular emphasis on persistent infections of the nervous system and of the hematopoietic and lymphoid systems. The laboratory is also studying the roles of persistent infection in the development of retrovirus-induced immunosuppression. Models being examined include prion diseases of various species, murine and human retroviruses.

The major research goals of the laboratory are to understand basic pathogenic mechanisms induced by these infections, to study immune or other defense mechanisms used by infected individuals against infections, and to develop drug therapies capable of reducing or eliminating such infections.

View all Division of Intramural Research laboratories

Systems Biology Consortium Resources

The Systems Biology Consortium for Infectious Diseases is a community of systems biologists who integrate experimental biology, computational tools and modeling across temporal and spatial scales to improve our understanding of infectious diseases. Through collaborative efforts, scientists test and validate hypotheses that drive innovation and discovery. The Consortium seeks to develop strategies that predict and alleviate disease severity and ultimately provide solutions to the world's most important health challenges.