This study collects specimens such as blood, urine, body fluids or secretions, skin swabs, or skin biopsies from volunteers for use in studies by the Vaccine Research Center. The samples are used for medical research, including the study of HIV, hepatitis, and other diseases; immune system responses, such as responses to vaccinations or infections; and for research on vaccine development.

Researchers need to collect specimens and images from individuals who have recently had a vaccination or recovered from an infection. These specimens and images are used to study different diseases and immune responses, and can be used to investigate ways to prevent or treat different medical conditions.

This is a screening study that is used to identify healthy volunteers who may be eligible to participate in other clinical trials at the Vaccine Research Center that evaluate investigational vaccines, monoclonal antibodies, and injection devices.

The NIAID Vaccine Research Center is looking for volunteers who have been recently infected with or have recovered from COVID-19 infection. We are also looking for those that plan to receive or received a COVID Vaccine to donate blood for research.

The Selection by Iterative Pathway Group and Network Analysis Looping (SIGNAL) platform is designed to facilitate robust hit selection from high-throughput genetic studies. SIGNAL takes an integrated, iterative approach to gene prioritization. By combining pathway and network methods, SIGNAL can sort data into low, medium, and high confidence tiers.