$6.9M NIAID Award to Fund Design, Testing of Hepatitis C Vaccine

Seeking Answers to Optimizing Influenza Vaccines in Older Adults Through New Study

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University of Connecticut
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Seeking Answers to Optimizing Influenza Vaccines in Older Adults Through New Study
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More Effective TB Vaccine Goal of Lovell’s Research

Cellular Waste May Supercharge Immune Cell Function

New Method Detects Gut Microbes That Activate Immune Cells

Buck Scientists Highlight New Perspective in How Immunity is Fine-Tuned Through Mechanics

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Buck Institute for Research on Aging
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Buck Scientists Highlight New Perspective in How Immunity is Fine-Tuned Through Mechanics
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ACTG Announces Launch Of ACTIV-2d, A Global Phase 3 Trial of The Novel Investigational COVID-19 Oral Antiviral Agent S‑217622

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ACTG
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ACTG Announces Launch Of ACTIV-2d, A Global Phase 3 Trial of The Novel Investigational COVID-19 Oral Antiviral Agent S‑217622

Collaborating with the NIH Center for Human Immunology, Inflammation, and Autoimmunity

Collaborative studies aim to leverage the high-dimensional technologies and expertise available in the CHI to enable systems-level characterization of immune phenotypes.  These collaborations can integrate several of the platforms at the CHI, with substantial support from study design to computational analysis. This work will be done in the context of a collaboration with intramural principal investigator(s) (PI), for which we welcome proposals from any NIH institute on any topic involving human samples. 

Epidemiology in the Division of Intramural Research

Epidemiology is a core science in public health that includes surveillance, observation, hypothesis testing, analytic research, and experiments and interventions. As the fundamental science of preventive medicine and public health, epidemiology has traditionally focused on disease causation through population studies. Epidemiologists develop and evaluate hypotheses about the effects of genetic, behavioral, environmental, and healthcare factors on human health and develop the knowledge bases for disease prevention and control programs. The field is interdisciplinary and has a methodology distinct from, but dependent on, biostatistics. Epidemiologists incorporate into their research the knowledge base and tools of other disciplines including the biologic sciences, clinical research, and other population sciences.

Main Areas of Focus

While our primary efforts focus on leading research relating to different aspects of infectious disease epidemiology and public health, epidemiologists at NIAID support research of relevance to the mission of NIAID, with approaches that include the following:

  • Design of clinical and population-based studies with appropriate methods and sampling strategies, focusing on reducing study bias and improving data collection
  • Analysis of randomized and non-randomized study cohorts using multivariable methods to identify host and pathogen contributions to infection and disease
  • Application of machine learning and other data science tools to study disease risk factors for selected infectious diseases and immune disorders
  • Molecular techniques to investigate immunological responses to emerging and re-emerging viral diseases
  • Research areas of particular interest include emerging viral pathogens, antimicrobial resistance, nontuberculous mycobacteria, malaria, SARS-CoV-2, Ebola, invasive fungal infections, inborn errors of immunity
Contact Information

Leah Katzelnick, Ph.D, M.P.H. – Seroepidemiology

Jennifer Kwan, Ph.D. – Infectious disease epidemiology, geospatial statistics

Rebecca Prevots, Ph.D. – Epidemiology of nontuberculous mycobacteria

Emily Ricotta, Ph.D., M.Sc. – Infectious disease epidemiology, data management

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