Systems Biology for Infectious Diseases Research

The Systems Biology for Infectious Diseases Research Programs develop and validate predictive models of infectious disease initiation, progression, and outcomes. These models are derived from the study of the architecture and dynamics of systems-wide host/pathogen molecular interaction networks during infection, using integrated datasets generated from a combination of “omics” technologies. The research findings will provide a deeper understanding of the overall complexity of the biological, biochemical, and biophysical molecular processes within microbial organisms as well as their interaction with the host.

Contact Information: 

Main Areas of Focus

  • To provide data and reagents that result from research conducted
  • To provide training for the broader infectious disease scientific community to promote the use of the systems biology approach


Office of Genomics and Advanced Technologies (OGAT), Division of Microbiology and Infectious Diseases (DMID) and the Systems Biology Steering Committee 

Infectious Disease Systems Biology Research Award Descriptions

FY13 Awards

FY18 Awards

Antibacterial Resistance Research Award Descriptions

Systems biology studies work specific to antibacterial resistance is carried out by by the following institutions. Select the name of the institution for a project description from NIH RePORTER.

Data Sharing Principles

All data and other resources generated by a systems biology center are owned jointly by all members of the center. Research data, protocols, and computational and statistical models must be made freely and publicly available to the scientific community.

Content last reviewed on June 29, 2018