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In the BPARS, we apply a systems biology approach to understand selection dynamics and host-pathogen interactions in the context of defined genetic immunodeficiency diseases. This approach integrates genomics, transcriptomics (RNA-seq), and metabolomic methods to identify and characterize specializations that occur during within-host adaptation.
Last Reviewed: January 21, 2025
Nico Contreras, Ph.D., of University of Arizona, F31 sample application
https://www.niaid.nih.gov/sites/default/files/f31-sample-application_nico_contreras.pdf
Last Reviewed: March 31, 2025
NIAID scientists developed tools to study evolution in enterovirusesāa virus group responsible for polio; hand, foot & mouth disease (HFMD); acute flaccid myelitis (AFM) & other diseases. Their findings may reveal pathways of viral evolution.
Published: December 10, 2024
Report of the Advisory Committee on Research on Womenās Health: Fiscal Years 2019ā2020
https://www.niaid.nih.gov/sites/default/files/ORWH-Biennial-Report2019-20.pdf
Last Reviewed: March 8, 2022
Publications going back to 2020 by scientists working with the NIH Center for Human Immunology, Inflammation, and Autoimmunity, including links.
Last Reviewed: September 10, 2024
Molecular and virological investigation of HIV-1 and HIV-2 and their interactions with host factors.
Last Reviewed: September 21, 2022
Jordan Report 20th Anniversary: Accelerated Development of Vaccines 2002
https://www.niaid.nih.gov/sites/default/files/jordan20_2002.pdf
Last Reviewed: December 31, 2002
We study how Salmonella Typhimurium interacts with mammalian host cells and the roles these interactions play in pathogenesis.
Last Reviewed: September 28, 2022
Olivia Steele-Mortimer, Ph.D., is Deputy Chief of the Laboratory of Bacteriology and Chief of the Salmonella-Host Cell Interactions Section. Salmonella enterica serovar Typhimurium (S. Typhimurium) is a common cause of gastroenteritis in humans. Our group studies how S. Typhimurium interacts with mammalian cells.
Last Reviewed: July 12, 2022
Klaus Strebel, Ph.D., is the Chief of the Viral Biochemistry Section at NIAID. The primary objective of the Viral Biochemistry Section is to investigate the biological and biochemical functions of HIV accessory proteins, in particular Vif, Vpu, and Vpx, and to define their role in virus replication. This includes both the detailed biological and biochemical characterization of the individual viral proteins as well as the investigation of their engagement with distinct host factors.
Last Reviewed: September 21, 2022
John Tsang, Ph.D., is a special volunteer in the Laboratory of Immune System Biology. He is the former Chief of the Multiscale Systems Biology Section and former Co-Director of the NIH Center for Human Immunology at NIAID.
Last Reviewed: October 25, 2024
Neuroinflammation during preclinical and clinical prion infection Influence of microglia and neurotoxic astrocytes on prion pathogenesis Alterations in cell populations and gene expression in the central nervous system and retina after prion infection Modeling Neuroborreliosis in human-derived neurons, astrocytes, and organoids
Last Reviewed: January 14, 2025
Seminars are available for viewing by members only as follows: NIH Member only: To view the videos, you must have NIH credentials to log onto Microsoft Stream. All 2021-2022 seminars will be recorded as they occur and in addition to the list below, you may view a complete list of recorded seminars 2020-current. For FDA Members only: To view the videos, you must have FDA credentials to log onto the
Last Reviewed: November 20, 2024
NBBTP/IRTA Fellows are trained specifically to support high containment research environments. Upon graduating from the program, NBBTP/IRTA alumni begin work as biorisk professionals with the knowledge and skills necessary to meet the scientific, regulatory, biocontainment, biosafety, engineering, communications, management, and public relations challenges associated with the conduct of research
Last Reviewed: January 21, 2025
The 206 th meeting of the National Advisory Allergy and Infectious Diseases Council (NAAIDC) convened virtually at 10:30 a.m. on Tuesday, January 30, 2024. Dr. Jeanne Marrazzo, Director, National Institute of Allergy and Infectious Diseases (NIAID) presided as chair. In accordance with the provisions of Public Law 92-463, the meeting was open to the public from 10:30 a.m. to 11:45 a.m. and from 1
Last Reviewed: May 21, 2024