Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge

This is a protocol to screen healthy volunteers for future and ongoing LMIV malaria drug, vaccine, or controlled human malaria infection (CHMI) trials. A complete medical history and blood and urine samples will be obtained for evaluation.

What Does the Study Involve?

You will complete an initial phone screen where you will learn more about the study and answer several yes/no medical history questions to review your eligibility.  If you are a good fit for the study, you will come into the clinic for a screening visit.  At the screening visit, you will review the informed consent, complete a physical exam, and have blood and urine samples collected to review your health. If you are enrolled in the study, you will have an annual phone call once a year to review your eligibility until you are enrolled in a malaria trial. 

Who Can Participate?

Healthy adults who:

  • Are 18 to 50 years old 
  • Have reliable access to the clinical center and are available in the area for more than 1 year 
  • Are not currently pregnant or breastfeeding 
  • Are interested in enrolling in a future malaria trial 

Where Is It Taking Place?

 OP8 at the NIH Clinical Center 

Is There a Cost?

No

Is Compensation Provided?

 Yes. Approximately $200 for the screening visit and $25 for annual phone screen 

Number of Visits Required 

Typically one screening visit at the clinic and then annual phone screens 

Steps To Participate?

Contact the LMIV Clinical Team  

Email: LMIVClinicalTrial@mail.nih.gov 

Phone: 240-627-3355 

Visit ClinicalTrials.gov for details

Visit ClinicalTrials.gov for details.

Contact Information

Contact the LMIV Clinical Team  

Email: LMIVClinicalTrial@mail.nih.gov 

Phone: 240-627-3355 

Participating in Research

Watch a series of short informational videos about participating in clinical trials. These videos are intended to help potential participants understand how research works, what questions they should consider asking, and things to think about when deciding whether or not to participate in a study.

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