Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (NEPTUNE)

We are asking you to join this study because you have had multiple outbreaks of warts and/or lesions caused by human papillomavirus (HPV). Medicine and surgery are not always effective to treat these outbreaks. We want to follow your HPV outbreaks over a long period of time to better understand how HPV infects the body and causes disease. 

Who Can Participate?

We plan to have approximately 500 people with HPV infection participate in this study. Subjects must have severe, disseminated, recurrent, and treatment-resistant HPV. We will also enroll approximately 250 healthy biological relatives of people with HPV. Participants need to be age 3 or older.

Where Is It Taking Place?

The study is taking place at the NIH Clinical Center in Bethesda, Maryland.

Is There a Cost?

There is no cost to participate.

Is Compensation Provided?

Participants will be compensated.

Contact Information

Office:  NIH Office of Patient Recruitment
Phone:  (800) 411-1222
TTY:  (866) 411-1010

Participating in Research

Watch a series of short informational videos about participating in clinical trials. These videos are intended to help potential participants understand how research works, what questions they should consider asking, and things to think about when deciding whether or not to participate in a study.

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