Natural History of Systemic and Nasal Mucosal Immunity to Influenza and SARS-CoV-2 in Adults After Vaccination

Are you an NIH staff member? If you have some time and have an interest in helping researchers make discoveries about COVID-19 and influenza, we need you!

We are interested in learning about long-term immunity in people who receive COVID-19 and/or flu vaccines.

What Does the Study Involve?

Participants will be asked to come to the NIH Clinical Center in Bethesda, Maryland, for a blood draw and nasal sample collection once a month for 12 months. Participants will receive an electronic questionnaire to complete and be contacted each month by the study team to review medical history.

Participants will not receive any vaccinations as part of this study.

Who Can Participate?

You may be eligible if you are:

  • ≥18 years old 
  • NIH staff
  • Planning to receive a COVID-19 vaccine and/or the current seasonal flu vaccine
  • Willing to have blood draws and nasal sample collections

Where Is It Taking Place?

The study is being conducted at the Warren Grant Magnuson Clinical Center (Building 10) on the NIH campus in Bethesda, Maryland.

Is There a Cost?

There is no charge to participate in the study.

Is Compensation Provided?

Yes, you will be compensated for your participation.  Travel reimbursement and meals are not provided.

Number of Visits


Steps To Participate

Email, or do one of the following:

  • Call our study coordinator at 301-594-0803
  • Call the NIH healthy volunteer office at 1-800-411-1222
  • Email Office of Patient Recruitment at

Visit for details.

Participating in Research

Watch a series of short informational videos about participating in clinical trials. These videos are intended to help potential participants understand how research works, what questions they should consider asking, and things to think about when deciding whether or not to participate in a study.

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