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Joshua R. Lacsina, M.D., Ph.D., is an assistant clinical investigator in the Vector Molecular Biology Section in the Laboratory of Malaria and Vector Research.

Last Reviewed: March 17, 2025

Klaus Strebel, Ph.D., is the Chief of the Viral Biochemistry Section at NIAID. The primary objective of the Viral Biochemistry Section is to investigate the biological and biochemical functions of HIV accessory proteins, in particular Vif, Vpu, and Vpx, and to define their role in virus replication. This includes both the detailed biological and biochemical characterization of the individual viral proteins as well as the investigation of their engagement with distinct host factors.

Last Reviewed: September 21, 2022

Today marks the 140th anniversary of the announcement by Dr. Robert Koch that tuberculosis (TB) is caused by the bacterium Mycobacterium tuberculosis. World TB Day is a reminder that this ancient disease remains a relentless killer. The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, affirms its commitment to the 2022 World TB Day theme

Published: March 24, 2022

Helen Su, M.D., Ph.D., is the Acting Chief of the Molecular Development of the Immune System Section and the Director, NIAID Clinical Genomics Program. Our laboratory investigates the molecular regulation of T lymphocytes, particularly as it relates to immunological tolerance, apoptosis, and autoimmune diseases such as multiple sclerosis, type 1 diabetes mellitus, and similar diseases. We use both molecular biology and cellular immunology techniques to pursue these investigations, with a focus on programs of cell death and survival, including apoptosis, autophagy, and necrosis mechanisms.

Last Reviewed: July 1, 2024

2012 update from NIAID on vaccine research for specific infectious diseases including Dengue, SARS, West Nile Virus, HIV/AIDS, and others

Last Reviewed: January 1, 2013

Last Reviewed: October 25, 2021

Jordan Report: Accelerated Development of Vaccines (2002) from NIAID includes updates on vaccine research for specific infectious diseases.

Last Reviewed: December 31, 2002

John Tsang, Ph.D., is a special volunteer in the Laboratory of Immune System Biology. He is the former Chief of the Multiscale Systems Biology Section and former Co-Director of the NIH Center for Human Immunology at NIAID.

Last Reviewed: October 25, 2024

Opportunistic fungal infections represent major causes of morbidity and mortality despite the administration of antifungal therapy. A better mechanistic understanding of host-fungal interactions will inform the development of improved immune-based strategies for the prevention, risk stratification, prognostication, vaccination, and treatment of vulnerable patient populations. In the Fungal

Last Reviewed: February 18, 2025

The Adams Research Group uses molecular and cellular techniques to manipulate spirochetes, sequence bacterial transcriptomes, characterize cellular processes, map regulatory networks, and study spirochetes during infection.

Last Reviewed: December 17, 2024

National Institutes of Health // Food and Drug Administration // Immunology Interest Group Newsletter March 2022

Last Reviewed: April 5, 2022

Peter Sun, Ph.D., is the Chief of the Structural Immunology Section. The major areas of research for the section are structural immunology; structure and function of natural killer-cell receptors, and structural mechanisms of HIV and host interactions.

Last Reviewed: April 11, 2024

Neuroinflammation during preclinical and clinical prion infection Influence of microglia and neurotoxic astrocytes on prion pathogenesis Alterations in cell populations and gene expression in the central nervous system and retina after prion infection Modeling Neuroborreliosis in human-derived neurons, astrocytes, and organoids

Last Reviewed: January 14, 2025

Joshua Tan, Ph.D., is the Chief of the Antibody Biology Unit (ABU). At the ABU, we aim to use cutting-edge technology to study B cells at the single cell level and to identify and characterize human monoclonal antibodies against a range of pathogens.

Last Reviewed: February 20, 2025

Seminars are available for viewing by members only as follows: NIH Member only: To view the videos, you must have NIH credentials to log onto Microsoft Stream. All 2021-2022 seminars will be recorded as they occur and in addition to the list below, you may view a complete list of recorded seminars 2020-current. For FDA Members only: To view the videos, you must have FDA credentials to log onto the

Last Reviewed: November 20, 2024

Dr. Barry received his Ph.D. in organic and bio-organic chemistry in 1989 from Cornell University. He joined NIAID following postdoctoral research at Johns Hopkins University. In 1998, he was tenured as chief of the TBRS. Dr. Barry is a member of several editorial boards, has authored more than 300 research publications in tuberculosis, and is the most cited researcher in the field, according to ScienceWatch.com.

Last Reviewed: January 12, 2024

This document summarizes a web-based iterative analysis platform integrating pathway and network approaches.

Last Reviewed: May 4, 2021

Profiles of postdoc fellows who participated in the Rocky Mountain Laboratories-Bethesda Postdoctoral Fellowship (Rocky-Beth) Program explain why they chose to participate and give an overview of their research.

Last Reviewed: January 30, 2024

Genetic and functional antibody evolution Effect of pre-existing immunity and autoreactivity on the maturation and function of B cell responses after infection and upon vaccination Immunogen selection, design, and vaccine development Antibody-based prophylactic and therapeutic countermeasures Immuno-monitoring Development of high-throughput assays Pathogens: HIV-1, flaviviruses, influenza virus

Last Reviewed: July 12, 2022

To carry out the research performed in the Molecular Development of the Immune System Section (MDISS), our team of dedicated scientific and clinical staff study patients using our combined expertise in genetics/genomics, molecular and cellular biology, biochemistry, and immunology.

Last Reviewed: March 20, 2025

The overall research objectives of the Tick-Pathogen Transmission Unit (TPTU) focus on studying tick- feeding biology to understand how salivary gland and midgut proteins impact blood feeding and facilitate the establishment, replication, and transmission of pathogens. Our goal is to identify molecular pathways that can be used as targets for the development of effective anti-tick and/or pathogen-blocking strategies.

Last Reviewed: November 29, 2023

Ronald N. Germain, M.D., Ph.D., is the Chief of the Laboratory of Immune System Biology and the Lymphocyte Biology Section (LBS). LBS has made numerous contributions to the understanding of the cell biology of antigen processing and presentation by MHC class I and especially class II molecules.

Last Reviewed: August 3, 2022

The NIAID DP2 New Innovators awardees are Early Stage Investigators (ESIs) who have proposed creative, novel, and high-impact research concepts that may be risky or at a stage too early to fare well in traditional peer review.

Last Reviewed: October 17, 2023

The Virus Persistence and Dynamics Section (VPDS) works to understand the persistence of HIV and other viruses in vivo by developing and applying advanced sequencing and other technologies.

Last Reviewed: September 26, 2022