Frank R. DeLeo, Ph.D., Chief
Olivia Steele-Mortimer, Ph.D., Deputy Chief
The Laboratory of Bacteriology (LB) studies bacteria that cause important human infections, including intracellular and arthropod-borne bacterial pathogens. In addition, LB conducts research with antibiotic resistant bacteria listed as serious or urgent threats in the National Action Plan for Combating Antibiotic-Resistant Bacteria. The ultimate goal of our research is to identify novel or improved strategies to control bacterial diseases, including development of diagnostics, vaccines, and therapeutics. LB maintains a flexible laboratory infrastructure to permit analysis of emerging bacterial pathogens and/or those of special interest.
See the National Action Plan for Combating Antiobiotic-Resistant Bacteria.
Pathogens Studied (selected)
- Borrelia burgdorferi
- Coxiella burnetii
- Chlamydia trachomatis
- Francisella tularensis
- Klebsiella pneumoniae
- Leptospira spp.
- Rickettsia rickettsii
- Salmonella enterica serovar Typhimurium
- Staphylococcus aureus
- Staphylococcus epidermidis
- Yersinia pestis
People
The Laboratory of Bacteriology includes the following principal investigators, staff scientists, and/or staff clinicians:
- Ashley Groshong, Ph.D.
Bacterial Physiology and Metabolism Unit - Catharine (Katy) Bosio, Ph.D.
Immunity to Pulmonary Pathogens Section - Frank R. DeLeo, Ph.D.
Pathogen-Host Cell Biology Section - Frank Gherardini, Ph.D.
Gene Regulation Section - David (Ted) Hackstadt, Ph.D.
Host-Parasite Interactions Section - Robert Heinzen, Ph.D.
Coxiella Pathogenesis Section - B. Joseph Hinnebusch, Ph.D.
Plague Section
- Carrie Mae Long, Ph.D.
Coxiella Pathogenesis Section - Michael Otto, Ph.D.
Pathogen Molecular Genetics Section - Patricia Rosa, Ph.D.
Molecular Genetics Section - Tais B. Saito, D.V.M., M.S., Ph.D.
Vector-Pathogen-Host Interaction Unit - Olivia Steele-Mortimer, Ph.D.
Salmonella-Host Cell Interactions Section - Lucas Tirloni, Ph.D.
Tick-Pathogen Transmission Unit
Sections and Units
The Laboratory of Bacteriology is comprised of the following sections and units:
- Coxiella Pathogenesis Section
Robert Heinzen, Ph.D., Chief - Bacterial Physiology and Metabolism Unit
Ashley Groshong, Ph.D. - Gene Regulation Section
Frank Gherardini, Ph.D., Chief - Host-Parasite Interactions Section
David (Ted) Hackstadt, Ph.D., Chief - Immunity to Pulmonary Pathogens Section
Catharine (Katy) Bosio, Ph.D., Chief - Molecular Genetics Section
Patricia Rosa, Ph.D., Chief - Pathogen-Host Cell Biology Section
Frank R. DeLeo, Ph.D., Chief
- Pathogen Molecular Genetics Section
Michael Otto, Ph.D., Chief - Plague Section
B. Joseph Hinnebusch, Ph.D., Chief - Salmonella-Host Cell Interactions Section
Olivia Steele-Mortimer, Ph.D., Chief - Tick-Pathogen Transmission Unit
Lucas Tirloni, Ph.D., Chief - Vector-Pathogen-Host Interaction Unit
Tais B. Saito, D.V.M., M.S., Ph.D., Chief