NIAID Site Search

As global temperatures rise, it has become more urgent to understand the interactions between climate, mosquitoes, and the pathogens mosquitoes transmit to humans. NIAID Now spoke to Luis Chaves, Ph.D., a 2023 Scholar with the National Institutes of Health (NIH) Climate Change and Health Initiative, about his work about the impacts of environmental change on the ecology of insect vectors and the diseases they transmit.

Published: August 18, 2023

Nico Contreras, Ph.D., of University of Arizona, F31 sample application

Last Reviewed: March 31, 2025

In the BPARS, we apply a systems biology approach to understand selection dynamics and host-pathogen interactions in the context of defined genetic immunodeficiency diseases. This approach integrates genomics, transcriptomics (RNA-seq), and metabolomic methods to identify and characterize specializations that occur during within-host adaptation.

Last Reviewed: January 21, 2025

NIH seeks research projects studying the ethical, legal, and social implications of human genetic or genomic research, including empirical qualitative and quantitative methods.

Published: December 20, 2023

NIAID scientists developed tools to study evolution in enteroviruses���a virus group responsible for polio; hand, foot & mouth disease (HFMD); acute flaccid myelitis (AFM) & other diseases. Their findings may reveal pathways of viral evolution.

Published: December 10, 2024

Office of Research on Women���s Health and NIH Support for Research on Women���s Health Report of the Advisory Committee on Research on Women���s Health: Fiscal Years 2019���2020 508-compliant PDF

Last Reviewed: March 8, 2022

Sumati Rajagopalan, Ph.D., is a Staff Scientist in the Molecular and Cellular Immunology Section. We are interested in the function of natural killer (NK) cells during early pregnancy. Our work has revealed a new, beneficial role of NK cells, which respond to fetal soluble HLA-G by promoting the vascular remodeling required for proper blood supply to the fetus.

Last Reviewed: December 21, 2012

Publications going back to 2020 by scientists working with the NIH Center for Human Immunology, Inflammation, and Autoimmunity, including links.

Last Reviewed: September 10, 2024

John Kehrl, M.D., is the Chief of the B-Cell Molecular Immunology Section. Our goals are to understand how G-protein-coupled receptors (GPCR) transduce signals to downstream effectors in immune cells, to discern the mechanisms that control these responses, and to determine the physiologic consequences of G-protein activation for lymphocyte function.

Last Reviewed: July 12, 2022

Jordan Report: Accelerated Development of Vaccines (2002) from NIAID includes updates on vaccine research for specific infectious diseases.

Last Reviewed: December 31, 2002

Single cell RNASeq and CITEseq analysis of innate and adaptive immune responses Dynamics of IG and TR repertoires in response to vaccination and infection Somatic hypermutation and antibody phylogenetics Impact of IG genetics on immune outcomes

Last Reviewed: July 12, 2022

John Tsang, Ph.D., is a special volunteer in the Laboratory of Immune System Biology. He is the former Chief of the Multiscale Systems Biology Section and former Co-Director of the NIH Center for Human Immunology at NIAID.

Last Reviewed: October 25, 2024

Klaus Strebel, Ph.D., is the Chief of the Viral Biochemistry Section at NIAID. The primary objective of the Viral Biochemistry Section is to investigate the biological and biochemical functions of HIV accessory proteins, in particular Vif, Vpu, and Vpx, and to define their role in virus replication. This includes both the detailed biological and biochemical characterization of the individual viral proteins as well as the investigation of their engagement with distinct host factors.

Last Reviewed: September 21, 2022

Olivia Steele-Mortimer, Ph.D., is Deputy Chief of the Laboratory of Bacteriology and Chief of the Salmonella-Host Cell Interactions Section. Salmonella enterica serovar Typhimurium (S. Typhimurium) is a common cause of gastroenteritis in humans. Our group studies how S. Typhimurium interacts with mammalian cells.

Last Reviewed: July 12, 2022

Candida auris, is an emerging healthcare-associated infection of growing public health concern. NIAID supports several researchers who are asking fundamental questions about the biology of C. auris. Today���s NIAID Now post features insights from NIAID-funded researchers, Jeniel Nett, M.D., Ph.D., associate professor of medicine and medical microbiology and immunology at University of Wisconsin-Madison, and Christina Cuomo, Ph.D., associate director of the Genomic Center of Infectious Diseases at the Broad Institute of Massachusetts Institute of Technology and Harvard University.

Published: September 23, 2022

The Integrative Bioinformatics of Immune Systems (IBIS) Core is the central bioinformatic resource for all repertoire and ���omics��� studies in the VRC. Research areas include transcriptomic analysis of both innate and adaptive immune cells, T cell receptor repertoire analysis, B cell receptor sequence and phylogenetic analysis, and analysis of immune cell population dynamics.

Last Reviewed: September 26, 2022

Innovative Drug Delivery for Spinal Cord Injury: NurExone's Exosome-Based siRNA Therapy with FDA Endorsement and Expanding Pipeline for Neuronal Regeneration November 14, 2024 Presenter: Dr. Lior Shaltiel, CEO, NurExone Biologic Inc. NurExone is leading the advancement of drug delivery systems for CNS indications and specially in spinal cord injury treatment. Their cutting-edge exosome-based siRNA

Last Reviewed: November 13, 2024

Neuroinflammation during preclinical and clinical prion infection Influence of microglia and neurotoxic astrocytes on prion pathogenesis Alterations in cell populations and gene expression in the central nervous system and retina after prion infection Modeling Neuroborreliosis in human-derived neurons, astrocytes, and organoids

Last Reviewed: January 14, 2025

Molecular and virological investigation of HIV-1 and HIV-2 and their interactions with host factors.

Last Reviewed: September 21, 2022

We study how Salmonella Typhimurium interacts with mammalian host cells and the roles these interactions play in pathogenesis.

Last Reviewed: September 28, 2022

Seminars are available for viewing by members only as follows: NIH Member only: To view the videos, you must have NIH credentials to log onto Microsoft Stream. All 2021-2022 seminars will be recorded as they occur and in addition to the list below, you may view a complete list of recorded seminars 2020-current. For FDA Members only: To view the videos, you must have FDA credentials to log onto the

Last Reviewed: November 20, 2024

Tongqing Zhou, Ph.D. is the Chief of the Structural Virology and Vaccinology Section (SVVS). SVVS seeks to apply structural biology to the development of an effective HIV-1 vaccine. Despite the enormous potential of atomic-level design���successfully used, for example, in the development of potent drugs against the HIV-1 protease���current vaccine development makes little use of atomic-level information. We are trying to change this.

Last Reviewed: March 19, 2025

Two U.S. Food and Drug Administration (FDA)���approved mRNA vaccines for COVID-19 have saved millions of lives. These vaccines were developed with NIH support and research on a protein found on SARS-CoV-2, the virus that causes COVID-19. Clinical trials for the COVID-19 vaccines in people were established in what seemed like record time. But in reality, more than 50 years of public and private

Last Reviewed: April 4, 2024