The Integrative Bioinformatics of Immune Systems (IBIS) Core is the central bioinformatic resource for all repertoire and “omics” studies in the VRC. Research areas include transcriptomic analysis of both innate and adaptive immune cells, T cell receptor repertoire analysis, B cell receptor sequence and phylogenetic analysis, and analysis of immune cell population dynamics.
Chaim A. Schramm, Ph.D.
Chief, Integrative Bioinformatics of Immune Systems Core
Ph.D., 2012, University of Pennsylvania
Dr. Schramm earned his Ph.D. from the University of Pennsylvania in 2012 and completed a postdoctoral fellowship at Columbia University prior to joining the VRC as a staff scientist in 2016. As chief of the IBIS Core, Dr. Schramm designs and leads large-scale scRNASeq analyses of innate and adaptive immune cells dynamics in infection and vaccination.
Christian G. Wake, Ph.D.
Chris is a bioinformatician for IBIS for the past two years. He provides general support to individuals with projects related to sequencing data analysis ranging from bulk analysis to single cell approaches including CITE-Seq. He is also focused on the establishment of standardization pipelines for general use to individuals within the VRC to ensure rapid turnaround from sequencing to initial look at the data.
Former Research Group Members
Lowrey Peyton (Dartmouth)