Rocky Mountain Laboratories (RML)

Some 3,000 feet higher above sea level than the National Institutes of Health (NIH) familiar brick campus in Bethesda, Maryland, and a 5-hour, 2,300-mile plane ride northwest of that point, lies Rocky Mountain Laboratories (RML), an NIH state-of-the-art biomedical research facility in Hamilton, Montana, a small but thriving community nestled between the Bitterroot and Sapphire Mountains. Read more about RML.

History of RML

Although the construction of the first building of The Rocky Mountain Labs was completed in 1928, RML evolved as a result of research on Rocky Mountain spotted fever that began around 1900, in the Bitterroot Valley of Western Montana. Early settlers of the valley were plagued with a deadly disease of unknown origin that seemed to be concentrated on the west side of the Bitterroot River. Read more about the history of RML.

RML Campus

Integrated Research Facility

To carry out research on these emerging and re-emerging pathogens in a safe environment, an Integrated Research Facility opened on the RML campus in 2008. The building, which contains high containment laboratories,employs the highest possible safety standards to protect scientists and the surrounding community. Building design complies with stringent federal and state regulations for construction, use, security, inspection, and certification.

Take a tour of a BSL-4 lab at RML

Tobacco-Free Campus

RML is committed to achieving a tobacco-free workplace for all employees and visitors.

RML federal employees have access to the Federal Occupational Health Services (FOHS) Tobacco Use Cessation Program. This program provides free tobacco cessation treatment services to smokers and other tobacco users who wish to quit through local clinics run by FOHS. The program is available at no cost to employees if their current health insurance plan does not cover over-the-counter treatment options for tobacco addiction.

All RML staff, including contractors, have access to the following free resources:

  • The National Network of Tobacco Cessation Quitlines (800-QUITNOW)
  • Smokefree.gov
  • Smoking cessation programs through the NIH Work/Life Center (301-435-1619)
  • Montana Tobacco Quit Line (800-QUIT-NOW)

If you have questions, email rmltobaccofree@niaid.nih.gov, and check out Taking Our Own Best Advice: Working Toward a Smoke-Free NIH.

Library

The RML Library gives RML staff members access to all the information they need to accomplish their research. The RML Library is open to the public by appointment only.

Library Catalog

Search the NIH Libraries Shared Catalog to locate books and journals in our collection. Many of the electronic resources will not be accessible to non-NIH website visitors, but most can be obtained through interlibrary loan.

Visiting the Library

The RML Library is open to members of the public who need to use the library's resources for their research. Appointments are required; to make an appointment, contact the Library Director, Taylor Robinson.

Use of Library Materials

Visitors may use the books and journals housed in the library. Access to computer-based resources may be restricted.

Library Contact

 Taylor Robinson, (406) 363-9211

Target Product Profiles for Antivirals

A team of subject matter experts from across the National Institutes of Health (NIH) and Biomedical Advanced Research and Development Authority (BARDA) has drafted Target Product Profiles (TPPs) for potential direct-acting antiviral therapeutics candidates targeting several key viruses of pandemic potential.  These TPPs should be considered ‘living documents’ that are never final but may be useful starting points for consideration by therapeutics developers who are drafting TPPs for their specific candidates.

Data Science Events

Find virtual and in-person data science events, webinars, and trainings from NIAID and the National Institutes of Health (NIH).

Hosting a data science event? Feature your event on this page by emailing the Office of Data Science and Emerging Technologies.

Seminar Series and Recurring Events

ScHARe Think-a-Thons

Hosted monthly by the National Institute of Minority Health and Health Disparities, Think-a-Thons are open to researchers at any level to learn about and discuss bias mitigation in artificial intelligence and health research. Follow the link to learn more about upcoming meetings and view past meeting recordings.

The Foundations of Biomedical Data Science Seminar Series

Speakers from a variety of biomedical data science disciplines present at this series weekly each Friday at noon ET. Publicly available recordings of past seminars can also be found at this link.

Bridge2AI Educational Materials

These materials include seminar series, blogs, and other educational resources from the NIH-funded Bridge2AI Consortium. Bridge2AI brings together experts across biomedical and behavioral research to develop FAIR datasets and ethical AI/ML practices.

Your Genome Report Is Negative—What You Need To Know Now

cartoon of a hospital administrator talking to two people about their test results
Credit: NHGRI/NIH

We’ve completed the analysis of your* genome sequence.

You may remember joining NIH study 17-I-0122. This study offered genetic testing called genome sequencing. We looked at nearly all of your DNA in detail. Genes are made from DNA and are the instructions for our bodies.

*If the person enrolled is a minor, then the term “you” refers to “you and/or your child” throughout this website.

A cartoon of two scientists discussing DNA in a large test tube.
Credit: NHGRI/NIH

We did not find a genetic cause for your symptoms.

We looked for differences or variants in your genes that could connect to your symptoms. We did not find anything to share with you.

A cartoon of two scientists drawing DNA on a board.
Credit: NHGRI/NIH

We also did not find any reportable secondary findings.

Secondary findings are variants in genes that may put a person at risk for rare, serious disorders that can be prevented or treated. Often, secondary findings are not related to your symptoms. Most of them have to do with risk for certain types of heart disease or cancer.

Learn more about secondary finding genes.

A cartoon of two doctors in lab coats standing in front of a big laptop screen with data on it.
Credit: NHGRI/NIH

No test is perfect. You may still have gene variants that are important for your health.

This test may have missed variants that are important for your health, including things that cause your symptoms. You should continue to work with your doctors to determine the best ways to care for your health, including having routine screenings. If a provider recommends further genetic testing, you should not assume it will be negative.

Some variants may not have been detected due to limitations in sequencing and analysis. The interpretation of your data is based on what we know now. New discoveries may change our analysis. We may provide updates to this report.

A cartoon of a hospital administrator talking to a woman in a wheelchair.
Credit: NHGRI/NIH

Next steps.

Please find your personal report in the patient portal. This report is a complex document that may be most helpful to your doctors.

Visit your patient portal

If you’d like to talk about your result, please email our team at NIAIDgenetics@mail.nih.gov.

Next Generation COVID-19 Vaccines

Project NextGen

Led by NIAID and the Biomedical Advanced Research and Development Authority (BARDA), part of the HHS Administration for Strategic Preparedness and Response (ASPR), Project NextGen is a coordinated effort where the federal government works with the private sector to advance the pipeline of new, innovative vaccines and therapeutics from labs into clinical trials with the intent to transition to the private sector later stage development and potential U.S.

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UAB Researchers Awarded $19.5 Million to Study Factors that Impact Sexual Health Among Women

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UAB Researchers Awarded $19.5 Million to Study Factors that Impact Sexual Health Among Women
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COVID Alters Respiratory Microbiota