Marzi Research Group

Highly pathogenic viruses, including filoviruses, continue to pose a significant threat to humans with their potential to cause global public health crises. We are investigating host-filovirus interactions to decipher mechanisms of pathogenesis. Additionally, we develop vaccines based on vesicular stomatitis virus for emerging viral infections. In 2020, we used the approved Ebola virus vaccine as a basis vector to develop SARS-CoV-2 vaccines demonstrating protective efficacy after a single vaccination in animal models.

Andrea Marzi, Ph.D.

Chief, Immunobiology and Molecular Virology Unit

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Education:

Ph.D., Friedrich-Alexander University Erlangen-Nurnberg, Germany

Dr. Marzi received her Ph.D. in virology from the Friedrich-Alexander University Erlangen-Nurnberg, Germany where she studied the glycoprotein-mediated entry of Ebola virus (EBOV) and HIV. After a short first postdoc in Winnipeg, Canada at the National Microbiology Laboratory-Public Health Agency of Canada, Dr. Marzi moved to the NIAID Rocky Mountain Laboratories in Hamilton, MT.

Photo of Andrea Marzi, Ph.D.

Hanna Anhalt, B.Sc. (She/Her/Hers)

Postbaccalaureate Fellow

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Hanna investigates the NK cell phenotypes after recombinant VSV infection in mice. Her plan is to attend medical school.

Paige L. Fletcher, Ph.D. (She/Her/Hers)

Postdoctoral Fellow

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Hanna investigates the NK cell phenotypes after recombinant VSV infection in mice. Her plan is to attend medical school.

A headshot of Paige Fletcher in a purple shirt.

Brody W. Mann, B.Sc. (He/Him/His)

INRO Postbaccalaureate Fellow

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Brody investigates the phenotypes of recombinant VSV-based vaccines in mice. His plan is to attend medical school.

Kyle L. O’Donnell, Ph.D. (He/Him/His)

Postdoctoral Fellow

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Development and efficacy testing of VSV-based vaccines against emerging viruses. Research focused on adaptive immunity including natural killer cell responses and how antibody Fc functions contribute to protection.

A headshot of Kyle O'Donnell in a plaid shirt.

Cecilia A. Prator, Ph.D. (She/Her/Hers)

Postdoctoral Fellow

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Languages Spoken: French

Cecilia uses immune organoids to study immune responses after vaccination and viral challenge to dissect the mechanistic features of human immunity. Her research interests include human immunology, infectious diseases, and organoid development.

A headshot of Cecilia Prator in a green shirt.

J. Fred Rhoderick, B.Sc. (He/Him/His)

Biologist

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Fred assists will all projects conducted in the lab.

A headshot of J. Fred Rhoderick in a plaid shirt.

Former Research Group Members

Wakako Furuyama, D.V.M., Ph.D. - Assistant Professor, Nagasaki University, Japan

Tylisha Gourdine, B.Sc. - Contractor, Vaccine Research Center NIAID

Amanda Griffin, Ph.D. - Microbiologist, LV-OOC, NIAID

Benjamin Kaza, B.A. - Graduate Student, Cornell University

Kyle Shifflett, B.Sc. - Graduate Student, University of North Carolina-Chapel Hill

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