Marzi Research Group

Immunobiology and Molecular Virology Unit

Highly pathogenic viruses, including filoviruses, continue to pose a significant threat to humans with their potential to cause global public health crises. We are investigating host-filovirus interactions to decipher mechanisms of pathogenesis. Additionally, we develop vaccines based on vesicular stomatitis virus for emerging viral infections and conduct preclinical efficacy studies in various animal models.

Andrea Marzi, Ph.D. (She/Her/Hers)

Chief, Immunobiology and Molecular Virology Unit

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Education:

Dr. rer. Nat. (Ph.D.), Friedrich-Alexander University Erlangen-Nürnberg, Germany

Diplom (M.Sc.), Freidrich-Alexander University Erlangen-Nürnberg,, Germany

Languages Spoken: German

Andrea is Chief of the Immunobiology and Molecular Virology Unit. She is a virologist by training, and her research focuses on the pathogenesis of filoviruses in animal models as well as the development and preclinical efficacy testing of countermeasures against emerging viruses. Ultimately, she hopes to advance vaccines and therapeutics against emerging viruses from the “bench to bedside.”

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Hanna Anhalt, B.Sc. (She/Her/Hers)

Postbaccalaureate IRTA Fellow

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Education:

B.Sc., University of Wisconsin-Madison

Languages Spoken: Spanish

Hanna investigates the NK cell phenotypes following recombinant vesicular stomatitis virus vaccination in mice. Her plan is to attend medical school.

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Olivia G. Durant, B.Sc. (She/Her/Hers)

Postbaccalaureate IRTA Fellow

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Education:

B.Sc., Northeastern University

Languages Spoken: Spanish

Olivia is interested in emerging infectious diseases, specifically filoviruses, and in pursuing a career that bridges rigorous scientific inquiry and clinical medicine. In the lab, she is studying the role of filovirus glycoproteins using recombinant vesicular stomatitis viruses and a mouse model.

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Paige L. Fletcher, Ph.D. (She/Her/Hers)

Postdoctoral IRTA Fellow

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Education:

Ph.D., University of Montana

B.Sc., Central Connecticut State University

Paige researches the pathogenicity of lesser-known filoviruses and investigates the efficacy of potential vaccines.

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Corey W. Henderson, B.Sc. (He/Him/His)

Biologist

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Education:

B.Sc., University of Maine at Fort Kent

Corey has extensive experience working with laboratory animals. He supports all projects in the lab, including bench work and animal procedures.

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Kyle L. O’Donnell, Ph.D. (He/Him/His)

Postdoctoral IRTA Fellow

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Education:

Ph.D., University of North Dakota

B.Sc., Minnesota State University, Mankato

Kyle uses flowcytometry and immunological assays to characterize the immune responses after VSV vaccination and viral challenge. His work has two primary areas of focus. The first is characterizing the complete functional humoral response, including neutralization and Fc-mediated functions. The second area of focus is the characterization of the cellular immune response analyzing early NK cell phenotypes and memory T-cell phenotypes.

Learn more about Kyle L. O’Donnell, Ph.D.