NIAID Site Search

Jordan Report: Accelerated Development of Vaccines (2002) from NIAID includes updates on vaccine research for specific infectious diseases.

Last Reviewed: December 31, 2002

Last Reviewed: August 6, 2019

Today marks the 140th anniversary of the announcement by Dr. Robert Koch that tuberculosis (TB) is caused by the bacterium Mycobacterium tuberculosis. World TB Day is a reminder that this ancient disease remains a relentless killer. The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, affirms its commitment to the 2022 World TB Day theme

Published: March 24, 2022

Sample application from Kenneth Coleman, Ph.D., for Small Business Innovation Research (SBIR) fast track grant.

Last Reviewed: November 25, 2022

Jordan Report: Accelerated Development of Vaccines (2007) from NIAID includes updates on vaccine research for specific infectious diseases.

Last Reviewed: August 6, 2019

Sample application from Vernita Gordon, Ph.D., for NIH standard independent research project grant (R01).

Last Reviewed: January 25, 2023

Our work involves the study of bacterial-host interactions using relevant cellular and animal model systems. We seek to elucidate immunologic mechanisms involved in these interactions and use this knowledge to advance preclinical therapeutic and vaccine development efforts.

Last Reviewed: December 6, 2024

We study how Salmonella Typhimurium interacts with mammalian host cells and the roles these interactions play in pathogenesis.

Last Reviewed: September 28, 2022

Development of diagnostics tools to detect exposure to pathogens, insects, and ticks The host immune response to insect-borne pathogens Pathogen-insect interactions Field expertise in epidemiology and pathogen transmission of insect-borne diseases

Last Reviewed: February 26, 2025

This document outlines systematic evaluation of nine monogenic autoinflammatory diseases.

Last Reviewed: April 7, 2021

National Institutes of Health // Food and Drug Administration // Immunology Interest Group

Last Reviewed: October 6, 2022

Olivia Steele-Mortimer, Ph.D., is Deputy Chief of the Laboratory of Bacteriology and Chief of the Salmonella-Host Cell Interactions Section. Salmonella enterica serovar Typhimurium (S. Typhimurium) is a common cause of gastroenteritis in humans. Our group studies how S. Typhimurium interacts with mammalian cells.

Last Reviewed: July 12, 2022

2012 update from NIAID on vaccine research for specific infectious diseases including Dengue, SARS, West Nile Virus, HIV/AIDS, and others

Last Reviewed: January 1, 2013

Peter Sun, Ph.D., is the Chief of the Structural Immunology Section. The major areas of research for the section are structural immunology; structure and function of natural killer-cell receptors, and structural mechanisms of HIV and host interactions.

Last Reviewed: April 11, 2024

Michail Lionakis, M.D., Sc.D., is Chief of the Laboratory of Clinical Immunology and Microbiology and the Chief of the Fungal Pathogenesis Section. The section's research focuses on 1) cellular and molecular factors that regulate the immune response against mucosal and invasive candidiasis and invasive aspergillosis in clinically relevant animal models and 2) better understanding the genetic and immune defects that underlie enhanced susceptibility to mucocutaneous and invasive fungal infections in humans.

Last Reviewed: February 18, 2025

February 2022 IIG Newsletter

Last Reviewed: March 8, 2022

Ronald N. Germain, M.D., Ph.D., is the Chief of the Laboratory of Immune System Biology and the Lymphocyte Biology Section (LBS). LBS has made numerous contributions to the understanding of the cell biology of antigen processing and presentation by MHC class I and especially class II molecules.

Last Reviewed: August 3, 2022

TBRS is a multidisciplinary group composed of chemists, microbiologists, veterinarians, imaging scientists, and clinicians with a shared objective of improving chemotherapy for tuberculosis (TB) patients. Projects span chemical biology, medicinal chemistry, host-pathogen interactions, animal models of experimental chemotherapy, and experimental medicine clinical studies in TB patients.

Last Reviewed: March 11, 2025

Dr. Barry received his Ph.D. in organic and bio-organic chemistry in 1989 from Cornell University. He joined NIAID following postdoctoral research at Johns Hopkins University. In 1998, he was tenured as chief of the TBRS. Dr. Barry is a member of several editorial boards, has authored more than 300 research publications in tuberculosis, and is the most cited researcher in the field, according to ScienceWatch.com.

Last Reviewed: January 12, 2024

Opportunistic fungal infections represent major causes of morbidity and mortality despite the administration of antifungal therapy. A better mechanistic understanding of host-fungal interactions will inform the development of improved immune-based strategies for the prevention, risk stratification, prognostication, vaccination, and treatment of vulnerable patient populations. In the Fungal

Last Reviewed: February 18, 2025

The Division of Intramural Research (DIR), a component of the National Institute of Allergy and Infectious Diseases, has long been at the forefront of research on immunologic, allergic, and infectious diseases. For more than 60 years, DIR scientists have discovered new pathogens, deciphered normal immune system function, identified aberrations underlying immunological diseases, and developed FDA

Last Reviewed: June 6, 2024

LBS has made numerous contributions to understanding cell biology of antigen processing and presentation by MHC class I and especially class II molecules. It also has examined recognition of these ligands by T cells with a focus on the signaling mechanisms involved in ligand discrimination. Various imaging technologies are used with more conventional molecular and cellular immunological methods.

Last Reviewed: September 30, 2022

The Mosquito Immunity and Vector Competence Section investigates the interactions between the mosquito immune system and Plasmodium parasites to understand how they affect malaria transmission.

Last Reviewed: September 23, 2022

Patrick E. Duffy, M.D., is Chief of the Laboratory of Malaria Immunology and Vaccinology, the Vaccine Development Unit, and the Pathogenesis and Immunity Section. The Pathogenesis and Immunity Section conducts human and animal studies of malaria pathogenesis and host immunity, including population-based studies in communities exposed to Plasmodium falciparum. Our research emphasizes pregnant women and children, the populations most susceptible to malaria morbidity and mortality, with collaborative cohort studies ongoing in Mali, Liberia and Guinea.

Last Reviewed: March 11, 2025