Division of Allergy, Immunology, and Transplantation High-Priority Areas of Interest for Small Business

NIAID encourages Small Business applications under topics related to asthma and allergies, autoimmune disease, immune system, radiation exposure, and transplantation. Below are areas of interest from the Division of Allergy, Immunology, and Transplantation (DAIT). The subject matter expert is available to answer questions and advise on the application process.

If you do not see your allergy-, immunology-, and transplantation-related topic here, the application may not be prioritized but will still be reviewed. Contact Michael Minnicozzi if you have any questions about your application and don’t see an appropriate subject matter expert below.

Asthma and Allergies Topics

Detection

Area of Interest
Novel approaches for detecting infants at risk for developing asthma and other allergic diseases.

Subject Matter Expert
Alkis Togias 

Diagnosis

Area of Interest
Developing food allergy diagnostic testing that can replace oral food challenges.

Subject Matter Expert
Wendy Davidson

New Forms of Allergen Immunotherapy for Food Allergies, Allergic Rhinitis, and Asthma

Area of Interest
Novel therapies that offer improved efficacy, safety, and a faster induction of clinical tolerance, i.e., the state where the effect of immunotherapy remains after therapy is discontinued.

Subject Matter Expert
Lisa Wheatley

Reagents and Animal Models

Area of Interest
Development of new reagents and non-murine animal models for allergy research.

Subject Matter Expert
Michael Minnicozzi

Autoimmune Disease Topics

Biomarkers

Area of Interest
Biomarkers to measure risk, disease activity, and therapeutic response in autoimmune diseases.

Subject Matter Expert
Thomas Esch

Diagnostic Criteria

Area of Interest
Standardized validated diagnostic criteria and outcome measures for autoimmune diseases correlated with disease activity.

Subject Matter Expert
David Johnson

HTP Assays

Area of Interest
High throughput assay of T-cell activity in autoimmune diseases.

Subject Matter Expert
John Peyman

Treatments

Area of Interest
Innovative treatments for autoimmune diseases.

Subject Matter Expert
John Peyman

Immune System Topics

Assays

Area of Interest
Single-cell and other sample-sparing assays for study of human immunology.

Subject Matter Expert
Halonna KellyTimothy Gondre-Lewis

Biomarkers

Area of Interest
Biomarkers of host immune defense.

Subject Matter Expert
Alison Deckhut Augustine

Mucosal Immunity

Area of Interest
Biomarkers to measure mucosal inflammation and response to therapy.

Subject Matter Expert
Annette Rothermel

Immunotherapeutic Antibodies

Area of Interest
Immunotherapeutic antibodies.

Subject Matter Expert
Stacy Ferguson

Reagents for Immunological Analysis of Non-mammalian and Underrepresented Mammalian Models

Area of Interest
Development and validation of reagents (e.g., antibodies, proteins, molecular probes) for the characterization of immune cells and their responses. Targeted species include non-mammalian models (e.g., arthropods, amphibians, fish, nematodes, and marine echinoids) and underrepresented mammalian models (e.g., guinea pig, ferret, cotton rat, bat, pig, and marmoset).

Subject Matter Expert
Joy Liu

Vaccine Adjuvants

Area of Interest
Development of novel vaccine adjuvants.

Subject Matter Expert
Wolfgang Leitner

Radiation Exposure Topics

Identification

Area of Interest
Identification of radiation exposure biomarkers and development of new biodosimetry methods and devices for triage of radiation-exposed people.

Subject Matter Expert
Merriline Satyamitra

Protection and Treatment

Area of Interest
Development of medical countermeasures to protect against, mitigate, and treat the short- and long-term effects of radiation exposure due to terrorist attack.

Subject Matter Expert
Andrea DiCarlo-Cohen

Treatment

Area of Interest
Development of novel or improved decorporation agents to remove radionuclides from the body following accidental inhalation, ingestion, or wound entry.

Subject Matter Expert
David Cassatt

 

Transplantation Topics

Immunomodulatory Agents and Biomarkers

Area of Interest
Immunomodulatory agents to prevent graft rejection and biomarkers to predict transplantation outcomes.

Subject Matter Expert
Nancy Bridges

MHC Typing

Area of Interest
Methods and analysis tools to facilitate high throughput, high resolution MHC typing in humans and nonhuman primates.

Subject Matter Expert
Monica Zamisch

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