Division of Allergy, Immunology, and Transplantation High-Priority Areas of Interest for Small Business

A bowl of peanuts.

A bowl of peanuts.

Credit: NIAID

NIAID encourages Small Business applications that focus on asthma and allergies, autoimmune disease, the immune system, radiation exposure, and transplantation.

The following topics from the Division of Allergy, Immunology, and Transplantation (DAIT) are NIAID Small Business Program high-priority areas of interest. If you do not see your allergy-, immunology-, or transplantation-related topic here, your funding application will still be reviewed, but it may not be prioritized.

If you have questions about these research topics or seek advice on the application process, please contact the specific subject matter experts listed below. You may contact Michael Minnicozzi with questions if a subject matter expert is not listed.

Subscribe to receive NIAID small business information and opportunity alerts at NIAID Email Updates. Open the Research Funding category, then open NIAID Funding Opportunities and select Small Business Awards (SBIR and STTR).

Asthma and Allergies

TopicsAreas of InterestSubject Matter Experts
DetectionNovel approaches for detecting infants at risk for developing asthma and other allergic diseases.Alkis Togias, Allergy, Asthma, and Airway Biology Branch
DiagnosisDeveloping food allergy diagnostic testing that can replace oral food challenges.Adora Lin, Allergy, Asthma, and Airway Biology Branch
New forms of allergen immunotherapy for food allergies, allergic rhinitis, and asthmaNovel therapies that offer improved efficacy, safety, and a faster induction of clinical tolerance (i.e., the state where the effect of immunotherapy remains after therapy is discontinued).Patty Fulkerson, Food Allergy, Atopic Dermatitis, and Allergic Mechanisms Section
Reagents and animal modelsDevelopment of new reagents and non-murine animal models for allergy research.Michael Minnicozzi

Autoimmune Disease

TopicsAreas of InterestSubject Matter Experts
BiomarkersBiomarkers to measure risk, disease activity, and therapeutic response in autoimmune diseases.Mireia Guerau
Diagnostic criteriaStandardized validated diagnostic criteria and outcome measures for autoimmune diseases correlated with disease activity.Jeffrey Rice
High-throughput (HTP) assaysHTP assay of T-cell activity in autoimmune diseases.Stacy Ferguson
TreatmentsInnovative treatments for autoimmune diseases.Stacy Ferguson

Immune System

TopicsAreas of InterestSubject Matter Experts
AssaysSingle-cell and other sample-sparing assays for the study of human immunology.Halonna Kelly; Timothy Gondre-Lewis
BiomarkersBiomarkers of host immune defense.Alison Deckhut Augustine
Mucosal immunityBiomarkers to measure mucosal inflammation and response to therapy.Deborah Hodge
Immunotherapeutic antibodiesImmunotherapeutic antibodies.Stacy Ferguson
Reagents for immunological analysis of non-mammalian and underrepresented mammalian modelsDevelopment and validation of reagents (e.g., antibodies, proteins, molecular probes) for the characterization of immune cells and their responses—targeted species include non-mammalian models (e.g., arthropods, amphibians, fish, nematodes, marine echinoids) and underrepresented mammalian models (e.g., guinea pig, ferret, cotton rat, bat, pig, marmoset).Joy Liu
Vaccine adjuvantsDevelopment of novel vaccine adjuvants.Wolfgang Leitner

Radiation Exposure

TopicsAreas of InterestSubject Matter Experts
IdentificationIdentification of radiation exposure biomarkers and development of new biodosimetry methods and devices for triage of radiation-exposed people.Merriline Satyamitra
Mitigation and treatmentDevelopment of medical countermeasures to protect against, mitigate, and treat the short- and long-term effects of radiation exposure due to terrorist attack.Andrea DiCarlo-Cohen
Removal of internal contaminationDevelopment of novel or improved decorporation agents to remove radionuclides from the body following accidental inhalation, ingestion, or wound entry.David Cassatt


TopicsAreas of InterestSubject Matter Experts
Immunomodulatory agents and biomarkersImmunomodulatory agents to prevent graft rejection and biomarkers to predict transplantation outcomes.Nancy Bridges
Major histocompatibility complex (MHC) typingMethods and analysis tools to facilitate HTP, high resolution MHC typing in humans and nonhuman primates. 


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