June 2023 DMID Council-Approved Concepts

Concepts represent early planning stages for program announcements, requests for applications, notices of special interest, or solicitations for Council's input. If NIAID publishes an initiative from one of these concepts, we link to it below. To find initiatives, go to Opportunities & Announcements.

Note: Council approval does not guarantee that a concept will become an initiative.

Table of Contents

Fiscal Year (FY) 2024 Division of Microbiology and Infectious Diseases (DMID) Concepts

FY 2025 DMID Concepts

Notice of Special Interest (NOSI)—Advancing Biomedical Research in Pulmonary Non-Tuberculous Mycobacterial (NTM) Infections

For the published notice of special interest, check the June 27, 2023 Guide notice, Notice of Special Interest (NOSI)—Advancing Biomedical Research in Pulmonary Non-Tuberculous Mycobacterial (NTM) Infections.

Notice of Special Interest (NOSI)—Promoting Research and Development of Vaccines Against Enteric Viruses

For the published notice of special interest, check the June 15, 2023 Guide notice, Notice of Special Interest (NOSI)—Promoting Research and Development of Vaccines Against Enteric Viruses.

Notice of Special Interest (NOSI)—Understanding Immune Evasion in Tickborne Diseases

For the published notice of special interest, check the July 24, 2023 Guide notice, Notice of Special Interest (NOSI): Understanding Immune Evasion in Tickborne Diseases.

Notice of Special Interest (NOSI)—Understanding Mucosal Immunity Against Enteric Eukaryotic Pathogens to Advance Discovery of New Interventions

For the published notice of special interest, check the June 15, 2023 Guide notice, Notice of Special Interest (NOSI)—Understanding Mucosal Immunity Against Enteric Eukaryotic Pathogens to Advance Discovery of New Interventions.

Notice of Special Interest (NOSI)—Using Targeted Degradation of Protein and Non-Protein Targets for the Development of Novel Anti-Infectives

For the published notice of special interest, check the October 31, 2023 Guide notice, Notice of Special Interest (NOSI)—Using Targeted Degradation of Protein and non-Protein Targets for the Development of Novel Anti-Infectives

Research Tools for Difficult to Culture Eukaryotic Pathogens

For the published request for applications, check the August 30, 2023 Guide announcement, Research Tools for Difficult to Culture Eukaryotic Pathogens (R61/R33, Clinical Trial Not Allowed).

Centers for Research in Emerging Infectious Diseases (CREID) Network

Request for Applications—proposed FY 2025 initiative

Contact:
Sara Woodson
sara.woodson@nih.gov

Objective: This concept would renew the Centers for Research in Emerging Infectious Diseases (CREID) Network (research center component), which aims to bring together multidisciplinary teams of domestic and international researchers to conduct integrated research that will help formulate coordinated strategies for detecting, controlling, and preventing emergence or re-emergence of viral infectious diseases while also developing and providing novel reagents, tools, and assays to facilitate outbreak responsive research.

Description: This concept will support the renewal of the CREID Network program, specifically the research center component (see the companion concept for the coordination center component), which is designed to improve our knowledge of emerging and re-emerging infectious diseases, complement and leverage existing NIAID international research efforts when possible, and allow NIAID to develop the flexibility and capacity to mount a rapid and effective research response to outbreaks wherever they occur. The research centers components will execute research projects that will lead to better understanding of emergence, natural history, incidence, and prevalence of emerging/re-emerging infectious diseases that will help formulate coordinated strategies for detection, control, and prevention. Research scope may span basic through translational and include field, clinical, and laboratory studies in the following topic areas:

  • Pathogen discovery and characterization
  • Pathogen surveillance in animals, vectors, and humans
  • Evaluation of factors related to pathogen transmission, maintenance, emergence, adaptation, and evolution (including role of climate change and/or social science)
  • Contemporary clinical disease progression or natural history of infection in humans
  • Immunologic responses to the infection
  • Modelling emergence risk
  • Development of reagents, diagnostic/detection tools, and critical animal models
  • Research that is foundational to or will enable the development of medical countermeasures to important emerging or re-emerging infectious diseases

The research centers will have the flexibility to study any emerging or re-emerging viral pathogen (RNA or DNA), but the primary focus will be on viral pathogens that are most likely to emerge/re-emerge in humans that are not already studied by other NIAID-funded networks and for which adequate countermeasures have not been developed. Each center will also be encouraged to leverage their capacity to respond to new outbreaks (as directed by NIAID), coordinate and collaborate with other CREID Network partners, and train/mentor the next generation of emerging infectious disease scientists and leaders.

Centers for Research in Emerging Infectious Diseases (CREID) Network Coordination Center

Request for Applications—proposed FY 2025 initiative

Contact:
Sara Woodson
sara.woodson@nih.gov

Objective: This concept will renew the Centers for Research in Emerging Infectious Diseases (CREID) Network Coordination Center, which plays a key role in facilitating coordination, communication, and collaboration among the Network’s centers and stakeholders. The overall goal of this network is to bring together multidisciplinary teams of domestic and international researchers to conduct integrated research that will help formulate coordinated strategies for detecting, controlling, and preventing emergence or re-emergence of viral infectious diseases while also developing and providing novel reagents, tools, and assays to facilitate outbreak responsive research.

Description: This concept will support the renewal of the CREID Network Coordination Center (see the companion concept for the research centers component). The Coordination Center will serve to advance, facilitate, and coordinate select scientific, communication, administrative, and leadership efforts within and on behalf of the network during both outbreak and non-outbreak periods.

Content last reviewed on