NIAID has awarded multiple projects for data science research, training, and technology development. The awarded projects listed below are coordinated by the Office of Data Science and Emerging Technologies (ODSET). Awarded projects from across NIAID will be added on an ongoing basis.
Software, Methods, and Technology Development
Early-Stage Development of Data Science Technologies for Infectious and Immune-mediated Diseases (U01 - Clinical Trial Not Allowed; RFA-AI-21-020)
- Semantic integration of protein epitopes and functional features for infectious and autoimmune disease knowledge discovery (1U01AI169243-01)
Exploratory Data Science Methods and Algorithm Development in Infectious and Immune-mediated Diseases (R21 - Clinical Trial Not Allowed; RFA-AI-21-035)
- Computational framework for analyzing and annotating single bacterium RNA-Seq data (1R21AI169350-01)
- Coupling Machine Learning with Agent-Based Modeling to Design a Universal Influenza Vaccine (1R21AI169364-01)
- Mechanism-guided drug repurposing for host-directed therapy of infectious diseases using interpretable and integrative ML (1R21AI169301-01)
- Real-Time High Resolution Method for Genomic Surveillance of ESKAPE pathogens (1R21AI169138-01)
Secondary Use of Existing Data
Secondary Analysis of Existing Datasets for Advancing Infectious Disease Research (R21 - Clinical Trial Not Allowed; PA-19-068)
- Multi-scale analysis of single cell sequencing data to dissect the complexity of influenza infections (1R21AI149013-01A1)
- Multi-scale analysis of single cell sequencing data to dissect the complexity of influenza infections (5R21AI149013-02)
- Delivering FAIR Datasets for the Neglected Parasite Trichomonas vaginalis and Studies in Comparative Genomics (1R21AI149449-01)
- Delivering FAIR Datasets for the Neglected Parasite Trichomonas vaginalis and Studies in Comparative Genomics (5R21AI149449-02)
- Finishing multiple genomes in EupathDB using Oxford Nanopore Single Molecule sequencing (1R21AI154386-01)
- Finishing multiple genomes in EupathDB using Oxford Nanopore Single Molecule sequencing (5R21AI154386-02)
- Signature of profiling and staging the progression of TB from infection to disease (1R21AI154387-01)
- Signature of profiling and staging the progression of TB from infection to disease (5R21AI154387-02)
- Intelligently predicting viral spillover risks from bats and other wild mammals (1R21AI164268-01)
- Intelligently predicting viral spillover risks from bats and other wild mammals (5R21AI164268-02)
Biomedical Repositories and Knowledgebases
Biomedical Data Repository (U24 - Clinical Trials Not Allowed; PAR-20-089, NOT-AI-20-044)
- Southern HIV and Alcohol Research Consortium Biomedical Data Repository (1U24AA029959-01)
Biomedical Knowledgebase - (U24 - Clinical Trials Not Allowed; PAR-20-097, NOT-AI-20-044)
- UniProt: A Protein Sequence and Function Resource for Biomedical Science (2U24HG007822-08)
- Virus Taxonomy: A Community Knowledgebase Supporting Virus Research (1U24AI162625-01)
- Virus Taxonomy: A Community Knowledgebase Supporting Virus Research (5U24AI162625-02)
Training and Education
Summer Institute for Research Education in Biostatistics and Data Science (R25 - Clinical Trial Not Allowed; RFA-HL-22-009)
- BU Summer Institute for Research Education in Biostatistics and Data Science (1R25AI166897-01)
- Irvine Summer Institute in Biostatistics and Data Science (1R25AI170491-01)
Training Modules to Enhance the Rigor, Reproducibility and Responsible Conduct of Biomedical Data Science Research (R25 – Clinical Trial Not Allowed; RFA-GM-20-001)