The mission of the Immunology Laboratory (IML) is to investigate novel aspects of the cellular immune response to pathogens in support of the rational development of a vaccine against HIV and other lethal human viral pathogens. It is the goal of the IML to rapidly advance the latest information on ways of manipulating the immune response to HIV into practical applications in clinical trials of prophylactic and therapeutic vaccines. In support of this effort, we emphasize a detailed analysis of the strength, breadth, plasticity, phenotype, and functional characteristics of the cellular immune response to HIV during natural infection and how it does or does not differ from the immune response during other viral infections or that is generated after vaccination.
View all research conducted at the Vaccine Research Center (VRC)
People
The Immunology Laboratory includes the following principal investigators, staff scientists, and/or staff clinicians:
- Eli Boritz, M.D., Ph.D.
Virus Persistence and Dynamics Section (VPDS) - Daniel Douek, M.D., Ph.D.
Human Immunology Section, Genome Analysis Core - Kathryn Foulds, Ph.D.
Nonhuman Primate Immunogenicity Core - Richard Koup, M.D.
Immunology Section
- Stephen Perfetto, M.S., MT (ASCP)
Flow Cytometry Core Section - Constantinos Petrovas, M.Sc., Ph.D.
Tissue Analysis Core - Mario Roederer, Ph.D.
ImmunoTechnology Section - Chaim A. Schramm, Ph.D.
Integrative Bioinformatics of Immune Systems Core - Robert Seder, M.D.
Cellular Immunology Section
Sections and Units
The Immunology Laboratory includes the following sections and cores:
- Cellular Immunology Section
Robert Seder, M.D., Chief - Flow Cytometry Core
Stephen Perfetto, M.S., MT(ASCP), Chief - Genome Analysis Core
Daniel Douek, M.D., Ph.D., Chief - Human Immunology Section
Daniel Douek, M.D., Ph.D., Chief - Integrative Bioinformatics of Immune Systems Core
Chaim A. Schramm, Ph.D. - Immunology Section
Richard Koup, M.D., Chief
- ImmunoTechnology Section
Mario Roederer, Ph.D., Chief - Nonhuman Primate Immunogenicity Core
Kathryn Foulds, Ph.D., Chief - Tissue Analysis Core
Constantinos Petrovas, M.Sc., Ph.D., Chief - Virus Persistence and Dynamics Section
Eli Boritz, M.D., Ph.D., Chief