The mission of the Immunology Laboratory (IML) is to investigate novel aspects of the cellular immune response to pathogens in support of the rational development of a vaccine against HIV and other lethal human viral pathogens. It is the goal of the IML to rapidly advance the latest information on ways of manipulating the immune response to HIV into practical applications in clinical trials of prophylactic and therapeutic vaccines. In support of this effort, we emphasize a detailed analysis of the strength, breadth, plasticity, phenotype, and functional characteristics of the cellular immune response to HIV during natural infection and how it does or does not differ from the immune response during other viral infections or that is generated after vaccination.
The Immunology Laboratory includes the following principal investigators, staff scientists, and/or staff clinicians:
- Eli Boritz, M.D., Ph.D.
- Joseph P. Casazza, M.D., Ph.D.
- Daniel Douek, M.D., Ph.D.
- Kathryn Foulds, Ph.D.
- Masaru Kanekiyo, D.V.M., Ph.D.
- Richard Koup, M.D.
- John Misasi, M.D.
- Stephen Perfetto, M.S., MT(ASCP)
- Constantinos Petrovas, M.Sc., Ph.D.
- Mario Roederer, Ph.D.
- Tracy J. Ruckwardt, Ph.D.
- Chaim A. Schramm, Ph.D.
- Robert Seder, M.D.