Moss Research Group

Bernard Moss, M.D., Ph.D.

Chief, Genetic Engineering Section
NIH Distinguished Investigator

Education:

Ph.D., Massachusetts Institute of Technology

M.D., New York University School of Medicine

Dr. Moss received his M.D. from the New York University School of Medicine, interned at the Children's Hospital Medical Center (Boston), and then earned a Ph.D. in biochemistry from the Massachusetts Institute of Technology. Dr. Moss is currently on the editorial boards of the Proceedings of the National Academy of Sciences, the Journal of Virology, and the NIH Catalyst. He is an adjunct professor at the University of Maryland.

Learn more about Bernard Moss, M.D., Ph.D.

Jeffrey L. Americo, M.S.

Biologist

Education:

B.S., Biology, American University
M.S., Toxicology, American University
M.S., Biotechnology, Johns Hopkins University

Involved in broad range of scientific projects associated with 1) the study of vaccinia virus and monkeypox virus infection and pathogenesis in animal models and 2) the characterization of host innate and adaptive immune responses to orthopoxviruses. More recent projects and interests include the development of a novel rMVA/SARS-CoV2 vaccine and identifying adaptive components of the immune system...

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Catherine Anne Cotter, M.S.

Biologist

Education:

M.S., Biotechnology, Johns Hopkins University
B.S., Biochemistry, Lancaster University (UK)

Basic poxvirus research. Study of vaccinia entry fusion proteins. Select agent work with monkeypox. Research into recombinant poxvirus vectored vaccines.

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Patricia Lewise Earl, Ph.D.

Staff Scientist

Education:

Ph.D., University of Iowa
BA, Lawrence University

Research interests include pathogenesis of vaccinia and monkeypox viruses and development of vaccine candidates against pathogens such as HIV and SARS CoV-2. Small animal models utilizing African dormice and CAST/EiJ mice have been developed for these purposes. Principal investigator in the Select Agent program for monkeypox and for an ACUC animal protocol for small animal models; experience in...

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George C. Katsafanas, B.A.

Biologist

Education:

Bachelor’s Degree, biology/biological sciences, Loyla University of Chicago

Languages Spoken: Greek

I was born in Megalopoli Greece, and at the age eight my family moved to Chicago. While attending college i worked in a diverse array of jobs in order to pay for tuition. After graduation i worked for a number of years at the University of Chicago as a biologist before continuing my career at the National Institutes of Health. All in all, for a total of thirty-five years and counting.

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Tatiana Georgia Koonin (Senkevich), Ph.D.

Staff Scientist

Education:

PH.D., Moscow State University

Investigation of the functions of vaccinia virus genes involved in the interaction with the host innate immune response.

Learn more about Tatiana Georgia Koonin (Senkevich), Ph.D.

Andrea S. Weisberg, B.S.

Microbiologist

Education:

B.S., Pennsylvania State University

In 1995, I came to the Laboratory of Viral Diseases as an electron microscopist, to study the entry, assembly, morphology, and egress of viruses.

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Yunliang Zhang, M.S.

Pre-doctoral Visiting Fellow

Education:

Ph.D. Candidate, University of Maryland

M.S., Indiana University of Bloomington

Languages Spoken: Chinese

I am a graduate student in Dr. Moss lab interested in investigating the mechanisms of virus replication and assembly, and the molecular machinery involved in the host-virus interaction, with particular focus on poxvirus.

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Members of Genetic Engineering Section Research Group

September 23, 2022

Marzi Research Group

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Highly pathogenic viruses, including filoviruses, continue to pose a significant threat to humans with their potential to cause global public health crises. We are investigating host-filovirus interactions to decipher mechanisms of pathogenesis. Additionally, we develop vaccines based on vesicular stomatitis virus for emerging viral infections and conduct preclinical efficacy studies in various animal models.

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Marzi Research Group

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Learn more about Andrea Marzi, Ph.D.

Andrea Marzi, Ph.D.

Chief, Immunobiology and Molecular Virology Section

Education:

Dr. rer. Nat. (Ph.D.), Friedrich-Alexander University Erlangen-Nürnberg, Germany

Diplom (M.Sc.), Freidrich-Alexander University Erlangen-Nürnberg, Germany

Vordiplom (B.Sc.), Friedrich-Alexander University Erlangen-Nürnberg, Germany

Languages Spoken: German

Andrea is the Chief of the Immunobiology and Molecular Virology Section. She is a virologist by training, and her research focuses on the pathogenesis of filoviruses in animal models as well as the development and preclinical efficacy testing of countermeasures against emerging viruses. Ultimately, she hopes to advance vaccines and therapeutics against emerging viruses from the “bench to bedside.”

Olivia G. Durant, B.Sc.

Postbaccalaureate IRTA Fellow

Education:

B.Sc., Northeastern University

Languages Spoken: Spanish

Olivia is interested in emerging infectious diseases, specifically filoviruses, and in pursuing a career that bridges rigorous scientific inquiry and clinical medicine. In the lab, she is studying the role of filovirus glycoproteins using recombinant vesicular stomatitis viruses and a mouse model.

Learn more about Olivia G. Durant, B.Sc.

B. Ryder Gathright, B.Sc.

Postbaccalaureate IRTA Fellow – INRO Program

Education:

B.Sc., Seattle University

Ryder is interested in emerging infectious diseases, such as filoviruses, and the molecular interactions between host and virus. In the lab, he is researching a heterologous prime-boost Ebola virus vaccination strategy and subsequent immunogenicity in a mouse model.

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Jil A. Haase (née Schrader), Ph.D.

Postdoctoral Visiting Fellow

Education:

Dr. rer. Nat. (Ph.D.), Ruhr University Bochum, Germany

B.Sc. and M.Sc., Ruhr University Bochum, Germany

Languages Spoken: German, Latin

Jil investigates underlying molecular factors that determine filovirus virulence and host-pathogen interaction. Her projects intend to unravel the underlying patterns leading to the pathogenesis observed in the infection macroenvironment, revealing novel factors for therapeutic intervention.

Learn more about Jil A. Haase (née Schrader), Ph.D.

image of Jil A. Haase (née Schrader), B.Sc.

Corey W. Henderson, B.Sc.

Biologist

Education:

B.Sc., University of Maine at Fort Kent

Corey has extensive experience working with laboratory animals. He supports all projects in the lab, including bench work and animal procedures.

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Kyle L. O’Donnell, Ph.D.

Postdoctoral IRTA Fellow

Education:

Ph.D., University of North Dakota

B.Sc., Minnesota State University, Mankato

Kyle uses flowcytometry and immunological assays to characterize the immune responses after VSV vaccination and viral challenge. His work has two primary areas of focus. The first is characterizing the complete functional humoral response, including neutralization and Fc-mediated functions. The second area of focus is the characterization of the cellular immune response analyzing early NK cell phenotypes and memory T-cell phenotypes.

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J. Fred Rhoderick, B.Sc.

Biologist

Education:

B.Sc., University of Tampa

Fred has decades of experience in the fields of molecular virology and cell biology. He assists with all projects conducted in the lab.

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Former Research Group Members

Hanna Anhalt, B.Sc. (postbac 2022 – 2024), Medical Student, University of South Carolina

Paige L. Fletcher, Ph.D. (postdoc 2020-2024), Associate Study Director, NIAID Integrated Research Facility, Frederick, Maryland

Wakako Furuyama, D.V.M., Ph.D. (postdoc 2017-2021), Assistant Professor, Nagasaki University, Japan

Tylisha Gourdine, B.Sc. (postbac 2020-2022), Contractor, Vaccine Research Center, NIAID

Amanda Griffin, Ph.D. (biologist 2019-2021), Microbiologist, LV-OOC, NIAID

Benjamin Kaza, B.A. (postbac 2021), Graduate Student, Cornell University

Brody Mann, B.Sc. (postbac 2022-2023), Medical Student, Tufts University School of Medicine

Cecilia Prator, Ph.D. (postdoc 2021-2023), Senior Scientist, Gingko Bioworks, Boston, Massachusetts

Kyle Shifflett, B.Sc. (postbac 2019-2021), Graduate Student, University of North Carolina-Chapel Hill

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August 27, 2024

McBride Research Group

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The DTVS studies mechanisms and strategies of HPV replication.

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McBride Research Group

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Learn more about Alison McBride, Ph.D.

Alison McBride, Ph.D.

Chief, DNA Tumor Virus Section

Education:

B.Sc., University of Glasgow, Scotland, UK
Ph.D., Imperial Cancer Research Fund and Imperial College, UK

Dr. McBride received a B.Sc. (Hons) in Molecular Biology from the University of Glasgow, Scotland, and a Ph.D. in Biochemistry from the Imperial Cancer Research Fund and Imperial College, England, studying Epstein-Barr virus. She began working on human and other papillomaviruses as a postdoctoral fellow in the National Cancer Institute and joined NIAID in 1994. She became a senior investigator in the Laboratory of Viral Diseases in 2000, and a section chief in 2001.

Dan Chen, B.S.

Biologist

Education:

Bachelor of Preventive Medicine, Harbin Medical University, Harbin, China

Languages Spoken: Mandarin

Dan studies the establishment and partitioning of HPV genomes in human keratinocytes. She has expertise in keratinocyte culture, DNA replication analysis and in situ imaging technologies.

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Ashley N. Della Fera, B.S.

Ph.D. Candidate and Pre-doctoral Fellow, University of Maryland

Education:

B.S., Cell and Molecular Biology, West Chester University of Pennsylvania

Ashley is investigating the role of viral chromatin assembly and PML-Nuclear bodies in HPV infection. She is interested in the intersection of nucleosome assembly pathways and intrinsic/innate immunity and studies this using in situ imaging techniques, immunoblotting, qPCR, and next-generation sequencing techniques.

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Jasmin L. Perkins, B.S.

Postbaccalaureate Fellow

Education:

B.S., Biology, Bowie State University, Bowie, MD

Jasmin is generating mutant and recombinant HPV genomes that will help elucidate key processes in the HPV infectious cycle. She is very interested in molecular genetics and has recently developed an interest in pediatric and pre/post-natal genetic counseling.

Learn more about Jasmin L. Perkins, B.S.

Alix Warburton, Ph.D.

Research fellow

Education:

Ph.D., Molecular & Clinical Pharmacology, University of Liverpool, Liverpool, U.K.
MRes, Biomedical Sciences, University of Liverpool, Liverpool, U.K.
B.Sc. (Hons), Human Anatomy & Cell Biology, University of Liverpool, Liverpool, U.K.

Alix investigates the mechanisms of HPV genome integration and the role of integration in oncogenic progression of HPV-associated cancers. This involves analysis of the epigenetic landscape of HPV infected cells by Next-Generation Sequencing and confocal microscopy techniques.

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Former Research Group Members

Sam Porter, Ph.D., post-doctoral fellow, University of Michigan

Tami Coursey, Ph.D. Scientist, Zymo Research

Simran Khurana, Ph.D., Staff Scientist, NCI

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September 23, 2022

Vega-Rodriguez Research Group

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The research goals in the Molecular Parasitology and Entomology Unit (MPEU) are to study the biology of the malaria parasite by characterizing essential vector-parasite and host-parasite interactions shaping malaria transmission. The long-term goal is to identify new targets that could be exploited for malaria interventions, including chemotherapy, vaccine development, and transgenic mosquitoes.

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Vega-Rodriguez Research Group

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Joel Vega-Rodriguez, Ph.D.

Earl Stadtman Investigator, NIH Distinguished Scholar
Chief, Molecular Parasitology and Entomology Unit

Education:

Ph.D., 2008, Rio Piedras Campus of the University of Puerto Rico, San Juan

Dr. Joel Vega-Rodriguez received his Ph.D. in molecular biology in 2008 at the Rio Piedras Campus of the University of Puerto Rico in San Juan. In 2009, he joined the laboratory of Dr. Marcelo Jacobs-Lorena at the Johns Hopkins Malaria Research Institute, where he did his postdoctoral training and later became a research associate. In 2018, Dr. Vega-Rodriguez became a Stadtman tenure-track investigator in the Laboratory of Malaria and Vector Research.

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Thiago Luiz Alves e Silva, Ph.D.

Research Fellow

Education:

Ph.D., Microbiology and Immunology, Federal University of Rio de Janeiro

Languages Spoken: Portuguese

Thiago has been a Research Fellow in the Laboratory of Malaria and Vector Research, NIH, since 2019. His research interests span vector-borne diseases, host-pathogen interactions, confocal microscopy, transcriptomics, and proteomics. Currently, he works in Dr. Joel Vega Rodriguez's laboratory, where he studies the development of Plasmodium parasites in the midgut, hemolymph, and salivary glands of...

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Emily Bencosme-Cuevas, Ph.D.

IRTA Research Fellow

Education:

Ph.D., Biomedical Sciences, 2023, Texas A&M University College of Veterinary Medicine and Biomedical Sciences, College Station, TX

Languages Spoken: Spanish

Dr. Emily Bencosme-Cuevas is passionate about vector-borne diseases, vector-host-pathogen interactions, and vaccine research and development. She began her research by studying the immune system of the Lone Star tick and continued during her Ph.D., focusing on the black-legged tick and the Lyme disease agent, Borrelia burgdorferi. After years of contributing to the tick research community, she...

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Rohit Chebbi, M.Sc.

Postbaccalaureate IRTA Fellow

Education:

M.Sc., 2024, BITS Pilani University, Goa, India

Languages Spoken: Kannada, Hindi

Rohit is working closely with his Molecular Parasitology and Entomology Unit colleague, Dr. Thiago Luiz Alves e Silva, to study interactions of the malaria parasite with proteins from the mosquito hemolymph and the role of these interactions during parasite transmission. He earned an integrated Master of Science in biological sciences from BITS Pilani University, India in 2024 and pursued his...

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Francis Monique de Souza Saraiva, Ph.D.

Visiting Postdoctoral Fellow

Education:

Ph.D., Biosciences, emphasis in Biochemistry, 2019, Rio de Janeiro State University, Brazil

M.Sc., Biosciences, emphasis in Biochemistry, 2015, Rio de Janeiro State University, Brazil

B.Sc., Biology, 2012, Rio de Janeiro State University, Brazil

Languages Spoken: Portuguese

Since her B.Sc., Dr. Francis M. de Souza Saraiva has developed projects about vector-borne diseases and the role of blood byproducts on the parasite-vector interaction. In 2022, she joined the laboratory of Dr. Joel Vega-Rodriguez in the Laboratory of Malaria and Vector Research as a Visiting Postdoctoral Fellow, where she is investigating the role of blood byproducts on the malaria parasite...

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Portrait of Francis Monique de Souza Saraiva, Ph.D., B.Sc., S.Sc.

Renuka Elizabeth Joseph, Ph.D.

Visiting Fellow

Education:

Ph.D., 2023, Pennsylvania State University, State College, PA

Sc.M., 2016, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD

B.Tech, 2013, Vellore Institute of Technology, Vellore, India

Languages Spoken: Malayalam

My research interests focus on understanding vector-pathogen interactions and developing therapeutics to combat these pathogens within their vectors. In the Vega-Rodriguez lab, my project involves identifying, characterizing, and developing mosquito salivary proteins, particularly apyrase, with the goal of creating a malaria transmission-blocking vaccine or prophylactic.

Learn more about Renuka Elizabeth Joseph, Ph.D.

Heather Michelle Kudyba, Ph.D.

Postdoctoral fellow

My research focuses on implementing various conditional knockdown/knockout systems to study essential genes in the mosquito midgut stage of Plasmodium falciparum.

Learn more about Heather Michelle Kudyba, Ph.D.

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Former Research Group Members

Tales Pascini, Ph.D., Visiting Postdoctoral Fellow, currently at Walter Reed Army Institute of Research

Yeong Je Jeong, M.S., Postbaccalaureate, currently at George Washington Medical School

Janet Olivas, B.S., Postbaccalaureate, currently a Graduate Student at New York University

Brendan Sweeney, B.S., Postbaccalaureate, currently at George Washington Medical School

Malika Saxena, B.S., Postbaccalaureate

Kelly, Hanner, B.S., Postbaccalaureate Trainee

Medard Ernest Kaiza, Ph.D., Visiting Postdoctoral Fellow

Zarna Rajeshkumar Pala, Ph.D., Visiting Postdoctoral Fellow

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August 22, 2024

Nita-Lazar Research Group

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Research in the Functional Cellular Networks Section focuses on understanding the changes that occur in the cell proteome in response to exogenous factors such as pathogen-derived molecules, cytokines, and chemokines, which alter the differentiation state of cells in the immune system or whose production characterizes specific disease states. We are especially interested in large-scale absolute quantitative measurements of immune cell signaling cascade components and in the characterization of post-translational modification (PTM) dynamics on a global scale. We use the resulting large datasets to create predictive models of molecular interactions using the Simmune software generated by the Computational Biology Section. The predictions of these models will in turn be employed to elucidate biological responses to stimuli at multiple scales of biological organization, including the cell, tissue, and, eventually, whole organism. 

We employ mass-spectrometry-based technology together with other proteomic and biochemical methods using state-of-the art equipment and technologies available in our laboratory and at NIH. 

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Nita-Lazar Research Group

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Aleksandra Nita-Lazar, Ph.D.

Chief, Functional Cellular Networks Section
Senior Investigator

Education:

Ph.D., 2003, University of Basel

Dr. Nita-Lazar received her Ph.D. in biochemistry in 2003 from the University of Basel for studies performed at the Friedrich Miescher Institute for Biomedical Research, where she analyzed protein glycosylation using mass spectrometry methods.

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Vanya Bhushan, Ph.D.

Exchange Visitor / Postdoctoral Fellow

Education:

Ph.D., 2022, National Dairy Research Institute

Languages Spoken: Hindi

Dr. Vanya Bhushan earned her Ph.D. from National Dairy Research Institute in 2022 and joined the Nita-Lazar lab in the spring of 2023. Her project at NIAID focuses on quantifying cellular protein abundance changes within subcellular compartments of host innate immune cells upon time course challenge with PAMPs/Vita-PAMPs from viable/non-viable whole cells, with activation of complex TLR/PRR signaling networks and their cross talk. Her interest primarily lies in quantitative mass spectrometry approaches to study cell signaling mechanisms.

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Jiraphorn Issara-Amphorn, Ph.D.

Postdoctoral Fellow

Languages Spoken: Thai

My research focuses on understanding molecular mechanism of macrophages in response to the pathogen derived molecules such as lipopolysaccharide (LPS). I’m also interested in the function of MARCKS and phospho-MARCKS in the regulation of inflammatory response in macrophages.

Learn more about Jiraphorn Issara-Amphorn, Ph.D.

Doeun Kim, Ph.D.

Postdoctoral Fellow

Education:

Ph.D., Kyungpook National University
M.S., University of Science and Technology (UST)
B.S., Yeungnam University

Languages Spoken: Korean

My research interests include identifying protein dynamics in the lipopolysaccharide (LPS)-driven TLR signaling pathway using proteomics approaches such as limited proteolysis, thermal proteome profiling, and quantitative proteomics (TMT and SILAC). Additionally, I’m interested in exploring the correlation between protein stabilities and protein phosphorylation.

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Nathan Paul Manes, Ph.D.

Staff Scientist

My research focus is quantitative proteomics using mass spectrometry. I use comparative proteomic profiling to discover host biological pathways affected by infection, and I use targeted proteomics to measure the absolute abundance of proteins to support biological pathway modeling and simulation.

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Jacob W. Pederson, B.S.

Predoctoral IRTA Fellow

Education:

B.S. and M.S., Microbiology (Oregon State University)

Using a combination of computational network analysis and systems biology principles we aim to understand how the underlying mechanisms of specific host-microbe interactions drive or protect against disease. This approach has led us to investigate how dietary fatty acids and microbes stimulate certain macrophage populations via the TLR pathway to promote inflammation in adipose tissue and decrease systemic insulin sensitivity, leading to onset of metabolic disease.

Learn more about Jacob W. Pederson, B.S.

Jose R. Pittaluga, Ph.D.

Postdoctoral Fellow

Education:

Ph.D., University of Buenos Aires

Languages Spoken: Spanish

Dr. Pittaluga joined the Nita-Lazar lab in the fall of 2024 to investigate the role of AOAH in neutrophil responses to LPS from various bacterial species. His research focuses on how AOAH modulates inflammation, utilizing a combination of approaches, including proteomics, to gain a comprehensive understanding of the pathways involved, with the ultimate goal of identifying key regulatory mechanisms...

Learn more about Jose R. Pittaluga, Ph.D.

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Sandhini Saha, Ph.D.

Exchange Visitor/Postdoctoral Fellow

Education:

Ph.D., Biotechnology, Regional Centre for Biotechnology, India

Languages Spoken: Bengali, Hindi

My research centers on advanced mass spectrometric techniques, combining relative and absolute quantification to explore complex cellular processes like growth, differentiation, and stress responses in disease biology. I am particularly focused on understanding disruptions in proteome homeostasis within the context of immunity, infection, and inflammation. My work aims to uncover proteome-wide...

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Sung Hwan Yoon, Ph.D.

Staff Scientist (Core)

Education:

Ph.D., University of Arizona

B.S., Seoul National University

Languages Spoken: Korean

Majored in analytical chemistry and my specialties are mass spectrometry, instrumentation, and proteomics.

Learn more about Sung Hwan Yoon, Ph.D.

Former Research Group Members

Virginie Sjoelund, Postdoctoral Visiting Fellow. Currently Associate Director of the Proteomics Core at the Barnett Institute, Northeastern University, Boston, MA.

Eunkyung An, Postdoctoral Visiting Fellow. Currently Program Manager in the Office of Cancer Clinical Proteomics Research (OCCPR) at the National Cancer Institute (NCI), NIH.

Marijke Koppenol-Raab, Postdoctoral IRTA Fellow. Currently Pharmaceutical Scientist, FDA.

Casey Daniels, Postdoctoral IRTA Fellow. Currently at DanceJam Productions.

Mohd M. Khan, Graduate Student (Graduate Partnership Program with the University of Maryland). Currently Manager (Cell & Gene Therapies Commercialization) at Deloitte Consulting US.

Thunnicha Ondee, Graduate Student (Graduate Partnership Program with Chulalongkorn University, Thailand). Currently Postdoctoral Fellow at Chulalongkorn University.

Sebastian Montalvo, Postbaccalaureate IRTA Fellow. Currently Business Strategy Senior Consultant Business Strategy Senior Consultant at Deloitte Consulting US.

Pauline Kaplan, Postbaccalaureate IRTA Fellow. Currently Medical Student, Kansas City University of Medicine and Biosciences, and Second Lieutenant, US Army.

Noah Kelner, Postbaccalaureate IRTA Fellow. Currently Graduate Student at the University of Rochester.

Caleb Bridgwater, Postbaccalaureate IRTA Fellow. Currently Graduate Student at Georgetown University.

Matthew Scandura, Postbaccalaureate IRTA Fellow. Currently Research Technician at Northern Arizona University.

Arthur Nuccio, Research Technician. Currently Scientist at Novartis.

Trisha Tucholski, Postdoctoral IRTA Fellow. Currently Scientific Officer at the National Academies.

Deepali Rathore, Postdoctoral Visiting Fellow. Currently Field Applications Scientist, Proteomics - Mid-Atlantic at Bruker.

Joseph G. Gillen, Postdoctoral IRTA Fellow. Currently Science Teacher for the Fairfax County Public Schools, Virginia.

Matthew James Marino, Postbaccalaureate IRTA Fellow. Currently Graduate Student, University of Delaware.

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December 02, 2024

Bosio Research Group

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The directive of the Immunity to Pulmonary Pathogens Section (IPPS) is to further our understanding of how virulent pulmonary pathogens, including Francisella tularensis, Bordetella pertussis and SARS-CoV-2 evade and inhibit protective immunity in the lung. Our overall goal is to utilize this information for development of novel therapeutics and vaccines directed against a variety of infectious diseases. Additionally, through comparative studies using other pulmonary pathogens we aim to gain a comprehensive understanding of regulation of innate and adaptive immune responses in the lungs with a special emphasis on metabolism.

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Bosio Research Group

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Catharine (Katy) Bosio, Ph.D.

Chief, Immunity to Pulmonary Pathogens Section

Education:

Ph.D., 1998, Colorado State University

B.Sc., 1993, Washington State University

Dr. Bosio graduated from Washington State University cum laude with a B.Sc. in 1993, completed her Ph.D. at Colorado State University, and postdoctoral fellowships at the Food and Drug Administration Center for Biologics Evaluation and Research and at the U.S. Army Medical Research Institute for Infectious Diseases. She joined NIAID in 2007; her laboratory studies the host response to pulmonary pathogens.

Learn more about Catharine (Katy) Bosio, Ph.D.

Forrest Jessop, Ph.D.

Biologist

Dr. Jessop primary interest is understanding how metabolic flux influences innate responses in the lung. Dr. Jessop utilizes a variety of infection models and both in vitro and in vivo models and techniques to characterize changes in metabolism after infection. Dr. Jessop’s goal is to use this information to design novel therapeutics for a wide variety of diseases.

Learn more about Forrest Jessop, Ph.D.

Lydia M. Roberts, Ph.D.

Staff Scientist

Dr. Roberts primary interest in the development of T cell immunity in the lung. By using an array of comparative models Dr. Roberts is dissecting out the optimal metabolic milieu required to engender long lived T cell responses in the lung with the goal of development of improved vaccines.

Learn more about Lydia M. Roberts, Ph.D.

Benji Schwarz, Ph.D.

Biochemist

Dr. Schwarz is the contact for the Immunometabolism Program housed within the IPPS.

Learn more about Benji Schwarz, Ph.D.

Tara Wehrly

Biologist

Ms. Wehrly provides broad support across all projects in the laboratory. Ms. Wehrly also serves as lab manager for the IPPS.

Learn more about Tara Wehrly

Former Research Group Members

Rebecca V. Anderson, Ph.D.

Amanda Griffin, Ph.D.

Timothy Bauler, Ph.D.

Joshua B. Alinger, MD/Ph.D.

Elliot Wyatt, BSc

Katrina Diaz, MD/Ph.D.

Kaitlin Stromberg, BSc

Ian Leighton, BSc

Jennifer Chase, MSc

Deborah Crane, MSc

Robin Ireland, MSc

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September 22, 2022

Fried Research Group

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The Molecular Pathogenesis and Biomarkers Section focuses on malaria pathogenesis in pregnant women and young children and identifying targets of protective immunity.

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Fried Research Group

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Learn more about Michal Fried, Ph.D.

Michal Fried, Ph.D.

Chief, Molecular Pathogenesis and Biomarkers Section

Education:

Ph.D., Hebrew University, Israel

M.Sc., Ben-Gurion University, Israel

Dr. Fried earned her Ph.D. in molecular parasitology at Hebrew University (Israel) and M.Sc. in biochemistry at Ben-Gurion University (Israel). Her groundbreaking work elucidated the molecular basis of placental malaria and described the model of protective immunity that is the basis of current pregnancy malaria vaccine development. This model of pregnancy malaria is currently expanded to studies of severe malaria in children carried out in longitudinal studies in Africa.

Sonal Kale, Ph.D.

Postdoctoral fellow

Education:

Ph.D., Kumaun University, Nainital, India

MSc, Jiwaji University, Gwalior, India

BSc, IEHE Barkatullah University, Bhopal, India

Languages Spoken: Hindi

During her Ph.D., Sonal measured naturally acquired antibodies against two malaria vaccine candidates, assessed genetic diversity in these vaccine candidates, as well as structural changes associated with mutations. Currently, Sonal is focused on studying malarial anemia pathogenesis in young children, conducting functional analysis of pathways associated with acute hemoglobin loss during malaria...

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Santosh A. Misal, Ph.D.

Staff Scientist

Education:

Ph.D., Biochemistry, Savitribai Phule Pune University, India

MSc, Biochemistry, Savitribai Phule Pune University, India

BSc, Chemistry, Savitribai Phule Pune University, India

Languages Spoken: Hindi, Marathi

Santosh has a strong background using various proteomics tools including chemical labeling, crosslinking, and global proteomic analysis. As a staff scientist at MPBS, his research focuses on utilizing proteomics tools to identify epitopes of malarial proteins targeted by naturally acquired antibodies. He is also applying proteomics tools to study host responses to malaria infection.

Learn more about Santosh A. Misal, Ph.D.

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Delesa Damena Mulisa, Ph.D., DVM

Postdoctoral fellow

Education:

Ph.D. in human genetics/bioinformatics from the University of Cape Town, South Africa

Doctor of veterinary medicine, Mekelle University, Ethiopia

MSc in Medical Microbiology, University of Addis Ababa, Ethiopia

Languages Spoken: Afan Oromo, Amharic

During his Ph.D., Delesa utilized genome-wide association studies, phylogenetics and post-GWAS analyses to identify traits associated with severe malaria. His current research interests include identifying Plasmodium falciparum membrane protein complexes associated with protective immunity in children using proteomics tools. He is also investigating human candidate gene polymorphisms that are...

Learn more about Delesa Damena Mulisa, Ph.D., DVM

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Manisha Pritam, Ph.D.

Postdoctoral fellow

Education:

Ph.D., Amity University, Lucknow, India

MSc, MGCGV Chitrakoot Satna M.P, India

BSc, DDU University Gorakhpur, India

Languages Spoken: Hindi

During her Ph.D., Manisha focused on using bioinformatic tools to design multi-epitope vaccines to different pathogens including Plasmodium, Leishmania, SARS-CoV-2, Rhizopus, and Enterococcus. As a postdoctoral fellow at MPBS, she is applying her experience to identify conserved PfEMP1 sequences across clinical parasite isolates that mediate parasite adhesion to endothelial receptors such as CD36...

Learn more about Manisha Pritam, Ph.D.

Former Research Group Members

Naissem Andemel (IRTA predoctoral fellowship), currently Kaiser/UCSF Internal Medicine/Preventive Medicine Residency Program and MPH

Patricia Gonzales, Ph.D. (Staff Scientist), currently RSO, Microbiology Review Branch, Division of Extramural Activities/NIAID/NIH

Brittany Pease, Ph.D. (Postdoc fellow) currently, Miltenyi Biotec, Technical Customer Trainer

Bethany Jenkins, Ph.D. (Postdoc fellow) currently Sanaria, staff scientist

Bartholomew Nyangahu, Ph.D. (Postdoc fellow) currently Egerton University Nakuru, Kenya, faculty position

Rachel Boone, BSc (Postbac fellow) currently University of Virginia BIMIS, Ph.D. Candidate

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September 22, 2022

Hourigan Research Group

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Our talented research group supports the vision and clinical and translational studies of the lab.

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Learn more about Suchitra Hourigan, M.D.

Suchitra Hourigan, M.D.

Chief, Clinical Microbiome Unit (CMU)
Lasker Clinical Research Scholar

Specialty(s): Pediatric Gastroenterology, Pediatrics
Provides direct clinical care to patients at NIH Clinical Center

Education:

M.D., University of Oxford, UK

Dr. Suchitra (Suchi) Hourigan was born in the UK and received her medical degree from the University of Oxford. She is a board-certified physician in pediatrics and pediatric gastroenterology, having completed her pediatric residency and pediatric gastroenterology fellowship training at the Johns Hopkins Hospital in Baltimore, MD. Prior to coming to NIH, Dr. Hourigan held faculty positions at the...

Mickayla Elle Bacorn, B.A., B.S.

IRTA Trainee

Education:

B.S., Biochemistry and Molecular Biology, University of Maryland, Baltimore County

B.A., Modern Language and Linguistics, University of Maryland, Baltimore County

Languages Spoken: Spanish

During her time at UMBC, Mickayla Bacorn was an NIH U-RISE trainee researching nutrient specificity in bacteria. She also completed a bioinformatic analysis of the active site evolution in coronaviruses. Currently, she is investigating microbiome-host responses in children with COVID-19 and the predictors of long-term health outcomes. Bacorn plans to pursue an M.D./Ph.D. graduate program and...

Learn more about Mickayla Elle Bacorn, B.A., B.S.

Victor Band, Ph.D.

IRTA Postdoctoral Fellow

Education:

Ph.D., Emory University

B.S., Tufts University

Victor received his B.S. from Tufts University and his Ph.D. from Emory University, where he studied antibiotic resistance within bacterial subpopulations to last-line drugs. His current research interests include the metabolic responses of bacteria to antibiotics and the downstream immune response.

Learn more about Victor Band, Ph.D.

Keona E. Banks, B.S.

Postbaccalaureate IRTA Trainee

Education:

B.S., Biology, Howard University

Keona received her B.S. in biology with a minor in chemistry from Howard University. Through her undergraduate courses, she became interested in maternal and infant health. Currently, she is investigating gut microbial structure and function in pregnant women and their offspring associated with adverse metabolic outcomes. After training at NIH, she would like to attend medical school to pursue an...

Learn more about Keona E. Banks, B.S.

Qing Chen, Ph.D.

Lab Manager

Education:

Ph.D., Chinese Academy of Sciences

Languages Spoken: Chinese

Qing received her B.S. in biology from Shandong University and her Ph.D. in cell biology from the Chinese Academy of Sciences, where she studied the interaction between mesenchymal stem cells and the immune system. She then completed postdoc training at NIEHS, investigating the role of poly(A)-tail length regulation in gene expression and cell fate in ESCs and germline stem cells. Her current...

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Diana Bori Jo, M.D.

Clinical Fellow in Pediatric Gastroenterology, Hepatology, and Nutrition

Education:

Fellowship in Pediatric Gastroenterology, Hepatology, and Nutrition, Children’s National Hospital

Pediatric Residency, INOVA Children’s Hospital

M.D., Frank H. Netter School of Medicine

B.S., Dalhousie University

Languages Spoken: Korean

Dr. Diana Jo received her medical degree from the Frank H. Netter School of Medicine. She is a board-certified pediatrician, having completed her pediatric residency at INOVA Children’s Hospital. She is currently a clinical fellow in pediatric gastroenterology, hepatology, and nutrition at Children’s National Hospital. She is interested in nutrition and the microbiome in relation to pediatric...

Learn more about Diana Bori Jo, M.D.

Phoebe Olivia LaPoint, B.S.

Postbaccalaureate IRTA Trainee

Education:

B.S., Biology, Elon University

Phoebe received her B.S. in biology with a minor in chemistry and business administration from Elon University. She first became interested in the gut microbiome during undergraduate research, where she studied the effects of changes of the gut microbiome on anxiety behaviors in male and female zebrafish. Currently, she is investigating gut microbial interactions in chronic inflammatory diseases...

Learn more about Phoebe Olivia LaPoint, B.S.

Shira Levy, M.A., CCRP

Program Manager

Education:

M.A., George Mason University
B.S., Columbia University
B.A., Jewish Theological Seminary

Shira Levy earned her master’s degree from George Mason University in neuroimaging, in addition to holding a B.S. degree in neuroscience and behavior from Columbia University and a B.A. in midrash from the Jewish Theological Seminary. Shira has worked in clinical research for over ten years and currently manages clinical research trials in the Clinical Microbiome Unit. Her research interests...

Learn more about Shira Levy, M.A., CCRP

Ranjani Namasivayam, Ph.D.

Research Fellow

Education:

Ph.D., University of Georgia

Ranjani received her Ph.D. from the University of Georgia, where she studied the evolution of apicomplexan parasites using next-generation sequencing and molecular biology techniques. She then did her postdoctoral training in the Laboratory of Parasitic Diseases at NIAID, investigating the role of the microbiota in Mycobacterium tuberculosis and SARS-CoV-2 infections. Her work at the Clinical...

Learn more about Ranjani Namasivayam, Ph.D.

Anal Patel, M.D.

Education:

M.D., American International Medical University

B.S., Manipal University

Languages Spoken: Gujarati, Hindi

Anal Patel received her B.Sc. in health science from Manipal University, followed by her medical degree from American International Medical University.

Learn more about Anal Patel, M.D.

Ruhika (Ru) Prasad, B.S.

Medical Research Scholar

Education:

B.S., Anthropology and Human Biology, Emory University

Languages Spoken: Telugu, Hindi

Ruhika (Ru) Prasad is an M.D./M.P.H. candidate at the Oregon Health and Science University and a 2024-2025 medical research scholar. Her research interests lie at the intersection of immunologic pathology and the maternal host response. Currently, she is investigating the development of environmental enteropathy in pregnant patients.

Learn more about Ruhika (Ru) Prasad, B.S.

Emily Robbins, D.O.

Allergy and Immunology Fellow

Education:

Pediatrics Residency, Zucker School of Medicine, Northwell Health

D.O., A.T. Still University

B.A., Colby College

Dr. Emily Robbins was born in Chicago and received her medical degree from A.T. Still University. She is a board-certified pediatrician, having completed her pediatric residency at the Zucker School of Medicine, Northwell Health in New York. Her long-term research goal includes understanding the relationship between the neonatal microbiome and its relationship with the later development of atopic...

Learn more about Emily Robbins, D.O.

Hector Romero Soto, B.S.

Postbaccalaureate Trainee

Education:

B.S., Biology, University of Puerto Rico at Cayey

Languages Spoken: Spanish

Hector Romero Soto received his B.S. in biology from the University of Puerto Rico at Cayey and just started his postbaccalaureate training at NIH. His research interests include the study of the microbiome and its interactions with the immune system to modulate the host’s health. After training at NIH, he would like to attend medical school to pursue an M.D./Ph.D. degree.

Learn more about Hector Romero Soto, B.S.

Rachel Elizabeth Strength, M.D.

Clinical Fellow in Medicine and Pediatric Infectious Diseases

Education:

NIH Fellowship in Medicine and Pediatric Infectious Diseases

Internal Medicine and Pediatrics Residency, University of Tennessee

M.D., Louisiana State University Health Sciences Center, Shreveport

B.S., Biomedical Engineering, Washington University in St. Louis

Dr. Strength is a board-certified internal medicine physician, board-eligible pediatrician, and clinical fellow in adult and pediatric infectious diseases at NIH and Children’s National Hospital. Her research interests include the long-term effects of infections in pregnant women and their children. She is studying how the microbiome changes through different stages of pregnancy and how infections...

Learn more about Rachel Elizabeth Strength, M.D.

Former Research Group Members

Cynthia Omoge Akagbosu, M.D., M.A.
Brynn Donnelly O’Laughlin, M.D.

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February 14, 2025

Leppla Research Group

Read more about Leppla Research Group

The Microbial Pathogenesis Section uses biochemical and genetic tools to study bacterial diseases and the factors contributing to pathogenesis. Research focuses on identification and analysis of bacterial virulence factors and their genetic regulation, and on their mechanisms of action. Structure-function analysis of bacterial proteins uses expression, mutagenesis, functional assessment, and structure determination by crystallography, etc. Knowledge from this work is used to repurpose bacterial protein toxins in the development of diagnostics, vaccines, and therapeutics.

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Learn more about Stephen H. Leppla, Ph.D.

Stephen H. Leppla, Ph.D.

Chief, Microbial Pathogenesis Section

Education:

Ph.D., University of Wisconsin

B.S., California Institute of Technology

Dr. Leppla earned a B.S. in biology from the California Institute of Technology and a Ph.D. in biochemistry from the University of Wisconsin. After postdoctoral study at the University of California-Berkeley and Brown University, he became a research scientist at the U.S. Army Medical Research Institute of Infectious Diseases in Frederick, Maryland. He moved to the National Institutes of Health in 1989 and to NIAID in 2003.

Ankur Bothra, Ph.D.

Visiting PostDoc Research Fellow

Education:

Ph.D., CSIR-Institutes of Genomics and Integrative Biology, India
M.Sc., Dept. of Molecular and Human Genetics, Banaras Hindu University, India
B.Sc. (Honors), Dept. of Botany, University of Delhi, India

Languages Spoken: Hindi

I am working on a research project where we aim to understand the role of environmental signals on regulating toxin production in B. anthracis.

Learn more about Ankur Bothra, Ph.D.

Mahtab Moayeri, Ph.D.

Associate Scientist, Microbial Pathogenesis Section

Education:

Ph.D., University of Wisconsin-Madison

Dr. Moayeri completed her Ph.D. in Medical Microbiology and Immunology at the University of Wisconsin-Madison. She has focused on anthrax toxin pathogenesis research as a postdoctoral fellow, staff scientist and associate staff scientist at NIH since 1999.

Learn more about Mahtab Moayeri, Ph.D.

Andrei P. Pomerantsev, Ph.D., D.Sc.

Staff Scientist

Education:

D.Sc., Biology, State Research Center for Applied Microbiology, Obolensk, Moscow
Ph.D., Chemistry, Lomonosov Moscow State University
B.S., Chemistry, Lomonosov Moscow State University

Languages Spoken: Russian

I am working in the field of molecular genetics.

Learn more about Andrei P. Pomerantsev, Ph.D., D.Sc.

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September 22, 2022

Katzelnick Research Group

Read more about Katzelnick Research Group

There are still no licensed, broadly protective vaccines against two of the most important flaviviruses, dengue viruses 1 to 4 (DENV1-4) and Zika virus (ZIKV). The only licensed dengue vaccine, Dengvaxia, was introduced as part of a mass-vaccination campaign of ~800,000 children in the Philippines before it was shown that the vaccine increases risk of severe dengue in some children. In the Viral Epidemiology and Immunity Unit, we use a multidisciplinary approach encompassing virology, immunology, and epidemiology to investigate protection against and susceptibility to emerging viruses to inform safe and effective deployments of vaccines. Our lab’s primary expertise is in seroepidemiology. We develop and apply immunological assays to measure biological determinants of disease outcomes in humans and analyze these data using statistical, computational, and epidemiological methods to address the following themes.

Antigenic and genetic viral evolution
Host immunological determinants of long-term protection and disease risk
Dynamics of viral transmission at the population level to inform disease prevention efforts

Our research focuses on the determinants of virus-specific immunity and the induction of the broadly cross-reactive immunity to DENV, which we believe serves as a model pathogen for other complex, immune-evasive viruses. Our work directly informs public health and preventative measures, including development of better next generation vaccines, design of interventions to increase the longevity of vaccine-induced immunity, and monitoring of how vaccines affect and are affected by viral evolution and transmission.

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Leah C. Katzelnick, Ph.D., MPH

Chief, Viral Epidemiology and Immunity Unit

Education:

Ph.D., 2016, University of Cambridge

Dr. Leah Katzelnick pursued a Ph.D. studying antigenic variation among dengue viruses at the University of Cambridge and the National Institutes of Health as an NIH OxCam Scholar and Gates Cambridge Scholar. After receiving her Ph.D. in 2016, she conducted her postdoctoral work at the University of California, Berkeley and University of Florida on determinants of dengue and Zika disease, spending a year in Ecuador and Nicaragua to work closely with research teams conducting longitudinal cohort studies. In September of 2020, Leah became an Earl Stadtman tenure-track investigator and NIH Distinguished Scholar in the Laboratory of Infectious Diseases in NIAID. She is Chief of the Viral Epidemiology and Immunity Unit.

Learn more about Leah C. Katzelnick, Ph.D., MPH

Rosie Aogo, Ph.D.

Postdoctoral Research Fellow

Education:

Ph.D., Mathematical Biology, University of New South Wales, Australia
MSc, Biomathematics, Stellenbosch University, South Africa
MSc, Mathematical Sciences, African Institute for Mathematical Sciences, South Africa
BSc, Maseno University, Kenya

Languages Spoken: Kiswahili

Rosie is a Postdoc Fellow at the Viral Epidemiology and Immunity Unit, LID, NIAID. Her current research focuses on using mathematical, statistical and machine learning tools to understand the within and between-host disease dynamics and in particular, diseases caused by dengue and Zika viruses. She is particularly interested in the dynamics of pathogens (bacteria, viruses, and parasites), their...

Learn more about Rosie Aogo, Ph.D.

Saba Firdous, M.S.

Laboratory Researcher

Education:

M.S., Biomedical Science, Hood College, Maryland

M.B.B.S., NTR University, India

Languages Spoken: Hindi, Urdu

Saba is a lab researcher and manager at the Viral Epidemiology and Immunity Unit. She has worked at the laboratory of Clinical Immunology and Microbiology, NIAID. She focused on characterizing glycogen synthase and glycogen phosphorylase mutant Chlamydial serovar L2 strains and understanding genetic mechanisms and pathogenesis. She studied the mechanism of early neutrophil response to...

Learn more about Saba Firdous, M.S.

Chloe M. Hasund, B.S.

Postbaccalaureate Research Fellow

Education:

B.S., Global and Public Health Sciences, Cornell University

Chloe is a Postbaccalaureate Research Fellow in the Viral Epidemiology and Immunity Unit, LID, NIAID. She joined the VEIU after spending some time working under Dr. Nancy J. Sullivan in the Biodefense Research Section, where she helped clarify the binding footprints of novel anti-Sudan ebolavirus therapeutics. Her research interests broadly include infectious diseases and epidemiology and...

Learn more about Chloe M. Hasund, B.S.

Melissa Law, B.S.N.

Registered Nurse; Protocol Nurse Coordinator

Education:

B.S.N., University of Maryland, School of Nursing

Melissa has extensive clinical research experience within NIAID caring for participants with primary immune deficiencies, HIV, parasitic diseases, eosinophilia, and Lyme disease. Roles have included medical/surgical nursing, case management and study coordination. She has also worked for the Davies Medical Center in San Francisco doing HIV research as well as with the Montgomery County Maryland...

Learn more about Melissa Law, B.S.N.

Kelsey Lowman, M.S.

Ph.D. Student, NIH Oxford Cambridge Scholars Program

Education:

M.S., Biological Sciences, University of Alabama
B.S., Microbiology, University of Alabama

Kelsey is an NIH-Cambridge scholar conducting her Ph.D. research under the co-mentorship of Dr. Leah Katzelnick (NIAID) at the NIH and Dr. Jonathan Heeney in the Department of Veterinary Medicine at Cambridge University. Her research explores the importance of re-exposure in driving a diverse and enduring immunity to viral pathogens. Her general research interests include viral immunology...

Learn more about Kelsey Lowman, M.S.

Patrick Mpingabo, M.D., Ph.D.

Postdoctoral Research Fellow

Education:

Ph.D., Medical Sciences/ Virology, Nagasaki University, Japan
M.D., University of Kinshasa Congo, DRC

Languages Spoken: French, Japanese

Patrick is a Postdoctoral Research Fellow in the Viral Epidemiology and Immunity Unit, LID, NIAID. His previous work focused on clinical trials of drugs for the treatment of malaria and the determinants of cell-type dependent virus release for New and Old-World Arenaviruses, including Junin virus, Machupo virus, Tacaribe virus, Latino virus, Pichinde virus and Lassa virus. He is currently focused...

Learn more about Patrick Mpingabo, M.D., Ph.D.

Camila D. Odio, M.D.

Clinical Fellow in Infectious Diseases

Education:

Internal Medicine Residency, Yale University

M.D., Cleveland Clinic Lerner College of Medicine

BA, Kenyon College

Languages Spoken: Spanish

Camila completed her clinical rotations in infectious diseases through NIAID’s fellowship program including training at Johns Hopkins, George Washington University Hospital, Medstar Georgetown, and the NIH’s Clinical Center.

Learn more about Camila D. Odio, M.D.

Guillermo L. Raimundi Rodriguez, B.S.

Postbaccalaureate Research Fellow

Education:

B.S., Industrial Microbiology, Universidad of Puerto Rico at Mayagüez

Languages Spoken: Spanish

Guillermo is an NIH Academy Enrichment Program (NAEP) Postbaccalaureate Fellow. He arrived after completing an extramural postbac program in Virginia Tech studying the immunopathology of Hepatitis E Virus, and now studies the determinants of neutralizing antibodies against dengue virus in individuals vaccinated against Zika virus. His research interests include infectious diseases and science...

Learn more about Guillermo L. Raimundi Rodriguez, B.S.

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Charlie Voirin, B.A.

Postbaccalaureate Research Fellow

Education:

B.A., Biology, Kenyon College

Charlie is a Postbaccalaureate Fellow in the Viral Epidemiology and Immunology Unit, LID, NIAID. He recently completed an undergraduate thesis in the molecular ecology of avian telomere dynamics, and his interest in disease ecology led him to the VEIU where he is excited to learn more about the virology, epidemiology, and immunology of dengue virus.

Learn more about Charlie Voirin, B.A.

Former Research Group Members

•   Fernando Echegaray, B.A. Medical Student at David Geffen School of Medicine at UCLA.
•   Sandra Mayer, Ph.D., D.V.M., M.Sc. Research Scientist at Walter Reed Army Institute of Research (WRAIR).
•   Janet Ogeneitsega Joseph, B.Sc. PhD student at Brown University.
•   Ana Coello Escoto, B.A. Scientist and Lab Manager at Astrazeneca.

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