The Microbial Pathogenesis Section uses biochemical and genetic tools to study bacterial diseases and the factors contributing to pathogenesis. Research focuses on identification and analysis of bacterial virulence factors and their genetic regulation, and on their mechanisms of action. Structure-function analysis of bacterial proteins uses expression, mutagenesis, functional assessment, and structure determination by crystallography, etc. Knowledge from this work is used to repurpose bacterial protein toxins in the development of diagnostics, vaccines, and therapeutics.
Stephen H. Leppla, Ph.D.
Chief, Microbial Pathogenesis Section
Ph.D., University of Wisconsin
B.S., California Institute of Technology
Ankur Bothra, Ph.D. (He/Him/His)
Visiting PostDoc Research Fellow
Ph.D., CSIR-Institutes of Genomics and Integrative Biology, India
M.Sc., Dept. of Molecular and Human Genetics, Banaras Hindu University, India
B.Sc. (Honors), Dept. of Botany, University of Delhi, India
Languages Spoken: Hindi
Mahtab Moayeri, Ph.D.
Associate Scientist, Microbial Pathogenesis Section
Ph.D., University of Wisconsin-Madison
Andrei P. Pomerantsev, Ph.D., D.Sc.
D.Sc., Biology, State Research Center for Applied Microbiology, Obolensk, Moscow
Ph.D., Chemistry, Lomonosov Moscow State University
B.S., Chemistry, Lomonosov Moscow State University
Languages Spoken: Russian