Kristie Research Group

Research in the Molecular Genetics Section focuses on the identifying components and determining mechanisms involved in transcription of herpes simplex virus (HSV) genes during the initiation of lytic infection and during viral reactivation from latency. This includes the integration of transcription factors, coactivators, epigenetic machinery, and transcription elongation factors that impact the expression of the first wave of viral genes.

In some instances, understanding the roles of these components can lead to translational studies that explore the potential of targeting essential/critical components as an approach to suppress HSV infection and disease.

Thomas M. Kristie, Ph.D.

Chief, Molecular Genetics Section

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Education: Ph.D., The University of Chicago, IL

Dr. Kristie received his Ph.D. from the Committee on Virology at the University of Chicago for his work with Dr. Bernard Roizman on the regulation of herpes simplex virus immediate early gene expression. As a postdoctoral fellow with Dr. Philip Sharp at the Center for Cancer Research, Massachusetts Institute of Technology, Dr. Kristie focused on the interaction of components involved in the...

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Thomas M. Kristie, Ph.D.

Jesse H. Arbuckle, Ph.D.

Senior Research Assistant

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Ph.D., Biomedical Sciences/Virology, 2011, University of South Florida College of Medicine

Dr. Jesse Arbuckle received his Ph.D. for his work on the chromosome integration of Human Herpesvirus-6A and 6B during latency. In the Molecular Genetics Section Dr. Arbuckle has examined the chromatin remodeler CHD3 and the histone methyltransferase EZH2 function in herpes simplex virus lytic gene expression. His research interests include using in vivo mouse models to understand the chromatin...

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Jodi L. Vogel, Ph.D.

Staff Scientist

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Ph.D., Biochemistry, 1989, The University of Alabama at Birmingham

Dr. Jodi Vogel received her Ph.D. for her work on functions of the bacteriophage Mu repressor protein. She then moved to the Laboratory of Susan Lindquist at the University of Chicago where she elucidated the role of heat shock proteins in the regulation of mRNA splicing in a yeast model system. Dr. Vogel joined the Molecular Genetics Section in 1994 where she has focused on characterization of...

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Former Research Group Members

  • Hua Peng, Ph.D.

    Principal Investigator, Key Laboratory of Infection and Immunity, Chinese Academy of Sciences

  • Bharat Khurana, Ph.D.

    Director, Regulatory Strategies, Takeda

  • Aarthi Narayanan, Ph.D.

    Associate Professor, George Mason University

    Director of Research, American Type Culture Collection

  • Mauricio Nogueira, Ph.D.

    Professor, Faculdade de Medicina de Sao Jose do Rio Preto

    International Faculty, University of Texas Medical Branch

  • Yu Liang, Ph.D.

    Director II, WuXi Biologics-Discovery

  • Ann-Marie Turner, Ph.D.

    Assistant Professor, University of North Carolina at Chapel Hill

  • Roberto Alfonso-Dunn, Ph.D.

    Research Scientist, TISCH MS Research Center of New York

  • Gaelle Kolb, Ph.D.

    Proposal Manager, Office of the Vice President for Research-University of Maryland

  • Zackary Whitlow, Ph.D.

    Principal Control Engineer, Helmerich and Payne

  • Andy Yanez, B.S.

    M.S. Student-University of Texas School of Public Health

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