Lisco Research Group

Primary and acquired immunodeficiencies like HIV/AIDS are associated with a high prevalence of skin and mucosal diseases caused by the Human Papillomaviruses (HPV), as well as an accelerated progression to HPV-related cancers. Dr. Lisco`s primary focus is on delineating the genetic, immunological, and molecular determinants of the persistence, regression, or progression of HPV-related diseases to inform innovative preventive and therapeutic strategies. The translational workflow of the laboratory is based on the integration of clinical protocols focused on the identification of clinical and epidemiological predictors of severe HPV-related diseases with studies on host genetics and tissue-specific immunopathogenesis at the skin and mucosal barriers, eventually informing personalized interventional clinical protocols.

Andrea Lisco, M.D., Ph.D.

Chief, Mucosal and Cutaneous Viral Immunopathogenesis Unit 
Lasker Clinical Research Scholar

Education:

M.D., University of Bari, Italy

Ph.D., University of Padua, Italy

Dr. Lisco earned his medical degree at University of Bari, Italy and pursued his research interests in viral immunology and pathogenesis of oncogenic viruses during his Ph.D. at the University of Padua, Italy and post-doctoral fellowship at the National Institutes of Health.

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Andrea Lisco, M.D., Ph.D

Derek MacMath, M.D.

Clinical Fellow

Education:

B.S., 2014, Molecular and Cellular Biology, Italian, Johns Hopkins University, Baltimore, MD

M.D., 2019, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

Internal Medicine/Pediatrics Residency, 2023, Baylor College of Medicine/Texas Children’s Hospital, Houston, TX

Dr. MacMath earned his medical degree at the University of Pennsylvania Perelman School of Medicine and completed his residency in internal medicine and pediatrics at Baylor College of Medicine. He is a clinical fellow in the NIAID Allergy & Immunology Fellowship Program.

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Photo of Derek MacMath, M.D.

Amay Shah, B.S.

Postbaccalaureate IRTA Fellow

Education:

B.S., 2023, Human Biology and Society + Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles

Amay Shah is currently working with Dr. Andrea Lisco on clinical and translational research focused on observing T-cell responses to HPV in patients with primary and acquired immunodeficiencies. His current project involves observing the HIV Reservoir in HPV-specific T cells and characterizing T-cell responses to HPV in patients with HPV and HIV co-infection.

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Peiying Ye, Ph.D.

Biologist

Languages Spoken: Chinese

Mapping the host determinants of HPV-related diseases in immunocompromised hosts (EPIC). Development of novel preventive and therapeutic strategies for severe HPV-related disease (NEPTUNE).

Learn more about Peiying Ye, Ph.D.

Peiying Ye, Ph.D., Biologist
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