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Sample application (R15): Artem Domashevskiy

https://www.niaid.nih.gov/sites/default/files/R15-Artem-Domashevskiy-Application.pdf
PDF Document | 4.71 MB
Sample application from Artem Domashevskiy, Ph.D., for Research Enhancement Award (R15) grant.

Last Reviewed: November 29, 2022

John P. Dekker, M.D., Ph.D.

Bacterial Pathogenesis and Antimicrobial Resistance Section
John P. Dekker, M.D., Ph.D., is the Chief of the Bacterial Pathogenesis and Antimicrobial Resistance Section. The emergence and spread of antimicrobial resistance (AMR) in bacteria has been recognized as a critical threat to public health. Many important classes of bacterial AMR undergo selection and evolution in the natural context of antibiotic treatment in a human host, though important features of host context are not commonly included in studies of AMR. One of the main areas of focus within the Bacterial Pathogenesis and Antimicrobial Resistance Section (BPARS) is the application of genomic techniques to understand the evolutionary mechanisms by which resistance emerges in this natural context.

Last Reviewed: November 21, 2023

Tickborne Diseases Information for Researchers

NIAID is conducting and supporting research to find better ways to diagnose, treat, and prevent tickborne diseases (TBD) as well as ways to control the tick populations that transmit microbes.

Highlights

colorful close up of the mouth of a tick
The mouth parts of a lone star tick are revealed in vivid detail. The center of the mouth (yellow) is covered with many tiny barbs. These barbs keep the tick securely lodged inside the host while feeding.
Credit
Credit: Igor Siwanowicz, Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA

NIH Strategic Plan for Tickborne Disease Research

The NIH Strategic Plan for Tickborne Disease Research proposes building on current trans-NIH efforts to better understand the complex interplay among host, tick, and pathogen factors that contribute to tickborne diseases and the body’s defenses against them. The plan aims to leverage this understanding to develop new tools that can more effectively prevent, diagnose, and treat TBDs.

NIH Awards Establish Pandemic Preparedness Research Network

The Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness network—called ReVAMPP—will focus its research efforts on “prototype pathogens,” representative pathogens from virus families known to infect humans, and high-priority pathogens that have the potential to cause deadly diseases. The pandemic preparedness research network will conduct research on high-priority pathogens most likely to threaten human health with the goal of developing effective vaccines and monoclonal antibodies.

Support for Research

Resources for Researchers

NIAID offers resources such as technologies available for licensing or collaboration, computer applications, and other tools and services to the general scientific community to advance basic, preclinical, and clinical research. See all resources for tickborne disease researchers. 

For researchers developing products such as diagnostics, vaccines, or drug therapies, NIAID provides repositories, genomics and bioinformatics services and tools, preclinical studies, and clinical evaluation that support each stage of the product development pathway. Read more about NIAID's support for infectious disease product developers.

Funding Opportunities

Contact the following staff within the Division of Microbiology and Infectious Diseases to learn about possible funding opportunities:

  • Dr. Sam Perdue, Chief, Basic Sciences Section, Rickettsial and Related Diseases Program Officer, Bacteriology and Mycology Branch
  • Dr. Nadine Bowden, Lyme Disease Program Officer, Bacteriology and Mycology Branch
  • Dr. Adriana Costero-Saint Denis, Program Officer, Vector Biology, Parasitology and International Programs Branch
Search all funding opportunities and announcements

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Bosio Research Group

Immunity to Pulmonary Pathogens Section
IPPS studies how virulent pulmonary pathogens, including F. tularensis, B. pertussis, & SARS-CoV-2, evade and inhibit protective immunity in the lung. Our goal is to use this information to devleop novel therapeutics and vaccines against a variety of infectious diseases. We also aim to understand regulation of innate and adaptive immune responses in the lungs with a special emphasis on metabolism.

Last Reviewed: September 22, 2022

Immunology Interest Group (IIG) Newsletter September

https://www.niaid.nih.gov/sites/default/files/iig-newsletter-sept-2022.pdf
PDF Document | 744.54 KB
National Institutes of Health // Food and Drug Administration // Immunology Interest Group

Last Reviewed: October 6, 2022

Ivanovic Research Group

Single Virion Biology and Biophysics Unit (SVBBU)
The Single Virion Biology and Biophysics Unit (SVBBU) investigates the molecular mechanisms of viral cell entry and progeny particle assembly.

Last Reviewed: August 28, 2024

Olivia Steele-Mortimer, Ph.D.

Salmonella-Host Cell Interactions Section
Olivia Steele-Mortimer, Ph.D., is Deputy Chief of the Laboratory of Bacteriology and Chief of the Salmonella-Host Cell Interactions Section. Salmonella enterica serovar Typhimurium (S. Typhimurium) is a common cause of gastroenteritis in humans. Our group studies how S. Typhimurium interacts with mammalian cells.

Last Reviewed: July 12, 2022

IIG Newsletter April 2022

https://www.niaid.nih.gov/sites/default/files/IIG-Newsletter-April_2022.pdf
PDF Document | 24.18 MB

Last Reviewed: May 5, 2022

Niki M. Moutsopoulos, D.D.S., Ph.D.

Human Barrier Immunity Section
Niki M. Moutsopoulos, D.D.S., Ph.D., is Chief of the Laboratory of Host Immunity and Microbiome and the Chief of the Human Barrier Immunity Section.

Last Reviewed: February 20, 2025

February 2022 Immunology Interest Group (IIG) Newsletter

https://www.niaid.nih.gov/sites/default/files/IIG-newsletter-Feb-2022.pdf
PDF Document | 4.36 MB
February 2022 IIG Newsletter

Last Reviewed: March 8, 2022

Sample application (SBIR Fast-Track): Coleman

https://www.niaid.nih.gov/sites/default/files/1r44ai112187-01a1_coleman.pdf
PDF Document | 5.25 MB
Sample application from Kenneth Coleman, Ph.D., for Small Business Innovation Research (SBIR) fast track grant.

Last Reviewed: November 25, 2022

Sample Application: Ratner Full Application

https://www.niaid.nih.gov/sites/default/files/ratnerfull.pdf
PDF Document | 7.57 MB

Last Reviewed: August 6, 2019

The Jordan Report: Accelerated Development of Vaccines 2007

https://www.niaid.nih.gov/sites/default/files/jordan2007.pdf
PDF Document | 3.65 MB
Jordan Report: Accelerated Development of Vaccines (2007) from NIAID includes updates on vaccine research for specific infectious diseases.

Last Reviewed: August 6, 2019

Bruce W. Chesebro, M.D.

LNII Special Volunteer
Bruce W. Chesebro, M.D., is a special volunteer in the Laboratory of Neurological Infections and Immunity. He is the former Chief of the TSE/Prion and Retroviral Pathogenesis Section.

Last Reviewed: January 13, 2025

NIAID Marks World Malaria Day

News Release
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), reaffirms our commitment to developing safe and effective medical tools against malaria, and, in the words of this year’s World Malaria Day theme, “Harnessing innovation to reducing the malaria disease burden and saving lives.”

Published: April 25, 2022

Moutsopoulos Research Group

Human Barrier Immunity Section

Last Reviewed: November 14, 2024

Barry Research Group

Tuberculosis Research Section
TBRS is a multidisciplinary group composed of chemists, microbiologists, veterinarians, imaging scientists, and clinicians with a shared objective of improving chemotherapy for tuberculosis (TB) patients. Projects span chemical biology, medicinal chemistry, host-pathogen interactions, animal models of experimental chemotherapy, and experimental medicine clinical studies in TB patients.

Last Reviewed: March 11, 2025

Tongqing Zhou, Ph.D.

Structural Bioinformatics Core
Tongqing Zhou, Ph.D., is Chief of the Structural Bioinformatics Core Section (SBIS), The SBIS seeks to apply the tools of computational biology and structural bioinformatics to the design of an effective HIV-1 vaccine.

Last Reviewed: March 22, 2024

Immunology Interest Group (IIG) Newsletter March

https://www.niaid.nih.gov/sites/default/files/IIGnewsletterMarch2021.pdf
PDF Document | 1.61 MB
This document outlines systematic evaluation of nine monogenic autoinflammatory diseases.

Last Reviewed: April 7, 2021

Veronique Nussenblatt, M.D, Sc.M., M.H.S

Infectious Disease Consult Service
COVID-19

Last Reviewed: March 6, 2024

Jessica R. Durkee-Shock, M.D., MHSc

Medical Virology Section
Severe viral infections in patients with inborn errors of immunity, with particular focus on herpes family and norovirus infections Characterization of genetic determinants of severe viral infections Therapeutics for severe viral infections in immunocompromised patients including viral specific T-cell therapies Clinical trials of human herpesvirus vaccines

Last Reviewed: June 28, 2022

Nita-Lazar Research Group

Functional Cellular Networks Section
Research focuses on understanding changes in the cell proteome in response to exogenous factors such as pathogen-derived molecules, cytokines, and chemokines and especially on large-scale absolute quantitative measurements of immune cell signaling cascade components and in the characterization of post-translational modification dynamics on a global scale.

Last Reviewed: December 2, 2024

Joseph Marcotrigiano, Ph.D.

Structural Virology Section
Joseph Marcotrigiano, Ph.D., is the Chief of the Structural Virology Section. Our laboratory is committed to understanding how positive-sense RNA viruses enter human host cells, replicate, and evade the immune response.

Last Reviewed: August 9, 2022

Leppla Research Group

Microbial Pathogenesis Section
The section uses biochemical & genetic tools to study bacterial diseases & the factors contributing to pathogenesis with focus on identification & analysis of bacterial virulence factors & their genetic regulation & on their mechanisms of action. Structure-function analysis of bacterial proteins uses expression, mutagenesis, functional assessment, structure determination by crystallography, etc.

Last Reviewed: September 22, 2022

Xu Research Group

Chemotaxis Signal Section
Dr. Xu’s group studies G protein-coupled receptors (GPCRs)’ signaling in chemotaxis of eukaryotic cell, metastasis of cancer cells, and viral infections, such as HIV infections and COVID-19.

Last Reviewed: September 28, 2022