Office of the Director

Dr. Taubenberger headshot

Acting Director Jeffery Taubenberger, M.D., Ph.D.

Credit: NIAID

Acting Director: Jeffery Taubenberger, M.D., Ph.D.

The Office of the Director (OD) determines Institute programs, plans, and policies and provides management, program analysis, and scientific program reporting services to the Institute, as well as scientific leadership, policy guidance, and overall operational and administrative coordination.

The OD serves as the chief liaison with the National Institutes of Health (NIH) director, other components of of the U.S. Department of Health and Human Services (HHS), other federal agencies, Congress, professional societies, voluntary health organizations, and other public health groups. It also coordinates the activities of NIAID extramural and intramural divisions.

Senior Leadership: Office of the Director

Senior Leadership: Extramural Divisions

Senior Leadership: Intramural Divisions

Division of Extramural Activities

Headshot of Kelly Poe

Kelly Poe, Ph.D.
Director, Division of Extramural Activities 

Credit: NIAID

The Division of Extramural Activities (DEA) serves the NIAID extramural research community and the Institute, through policy oversight, peer review, and the management of grants and contracts, including research training, small business, and international awards.

DEA staff interact with grantees, institutional officials, contractors, peer reviewers, committee members, applicants, and NIAID and National Institutes of Health (NIH) staff. In addition, DEA works closely with the NIH Office of Extramural Research and other NIH Office of the Director components to coordinate, implement, and develop new extramural policies for research grants and contracts.

Through the DEA Scientific Review Program, the division conducts initial peer review of contract proposals and grant applications with Institute-specific requirements: program projects, cooperative agreements, training and career development grants, and research and development contracts, as well as responses to requests for applications and requests for proposals.

DEA also oversees the National Advisory Allergy and Infectious Diseases Council and other chartered committees; disseminates information to the extramural community through the Grants & Contracts section of the NIAID website and the newsletter NIAID Funding News; and purchases equipment and supplies for NIAID intramural laboratories

Research Rules & Policies

Policies and procedures are essential to any clinical research enterprise. In this regard, the Division of Extramural Activities has compiled a number of standard operating procedures (SOPs) that support the mission of extramural research.


See all DEA Research Rules & Policies

Funding Opportunities

NIAID and NIH offer a number of funding opportunities, including grants and contracts, to conduct basic research, preclinical development, or clinical evaluation.


See all Funding Opportunities Supported by NIAID

Division of Clinical Research

Photo of Dr. Clifford Lane

H. Clifford Lane, M.D.
NIAID Deputy Director, Clinical Research and Special Projects
Director, Division of Clinical Research

Credit: NIAID

The Division of Clinical Research (DCR) plays an integral role in facilitating the efficient and effective performance of NIAID research programs on both the domestic and the international level. This is accomplished through a multi-faceted approach to the provision and support of services vital to the research infrastructure that include oversight and management of intramural clinical research, program planning and management, regulatory monitoring and compliance, statistical consultation and research methodology, and clinical research capacity building.

DCR vision is to facilitate high quality, state-of-the-art NIAID clinical research in the areas of allergic, immunologic, and infectious diseases. DCR provides multi-disciplinary trans-NIAID services for facilitating clinical research and managing special projects as directed by NIAID leadership.

Networks

NIAID encourages partnerships among other agencies and foundations, private industry, federal and local government, and other organizations with similar goals to help build and sustain research infrastructure and to translate and implement research findings as public health practices.

Such partnerships ensure that the research will lead to findings that are ultimately feasible and meaningful for impacted communities. NIAID is deeply committed to local and international research collaboration that are mutually beneficial and scientifically productive.


Read more about NIAID-supported collaborations and partnerships that further the work of the Division of Clinical Research

Division of Allergy, Immunology, and Transplantation

Photo of Daniel Rotrosen, M.D

Daniel Rotrosen, M.D.
Director, Division of Allergy, Immunology, and Transplantation

Credit: NIAID

The Division of Allergy, Immunology, and Transplantation (DAIT) explores how the immune system maintains health and, under abnormal conditions, also contributes to disorders. DAIT supports basic and clinical research to improve our understanding of the causes of immunologic diseases and to develop better diagnostic, treatment, and prevention strategies.

DAIT supports basic and clinical research to increase our understanding of the causes and mechanisms that lead to the development of allergic and immunologic diseases and to expand knowledge that can be applied to improving techniques of diagnosis, treatment, and prevention.

See Allergy, Immunology, and Transplantation Research.

Organization

Networks

NIAID partners with leaders in the fields of allergy, immunology, and transplantation research to better understand the associated diseases and conditions and move forward toward better prevention, diagnosis, and treatment.


See NIAID-supported networks related to DAIT research

Funding Opportunities

NIAID and NIH offer a number of funding opportunities, including grants and contracts, to conduct basic research, preclinical development, or clinical evaluation.

Potential Funding Opportunities


See all Funding Opportunities

Resources for Researchers

DAIT supports a comprehensive set of resources for researchers. Their purpose is to facilitate the preclinical and clinical research needed to translate the ideas generated through basic research into safe and effective drugs, vaccines, and diagnostics to control and prevent allergic, immunologic, or transplantation-related diseases and conditions.


See all DAIT resources

Research Rules & Policies

Policies and procedures are essential to any clinical research enterprise. In this regard, the Division of Allergy, Immunology, and Transplantation has standardized and harmonized operational procedures across research areas.


See all DAIT Research, Rules & Policies

Vaccine Research Center

Theodore C. Pierson, Ph.D.

Ted C. Pierson, Ph.D.
Director, Vaccine Research Center

Credit: NIAID

The Dale and Betty Bumpers Vaccine Research Center (VRC) at the National Institutes of Health (NIH) was established to facilitate research in vaccine development. The VRC is dedicated to improving global human health through the rigorous pursuit of effective vaccines for human diseases. Established by former President Bill Clinton as part of an initiative to develop an AIDS vaccine, the VRC is a unique venture within the NIH intramural research program. Initially spearheaded by NIAID, the National Cancer Institute, and the NIH Office of AIDS Research, the VRC is now part of the NIAID organization.

The VRC’s mission is to discover and develop novel vaccines and biologics targeting infectious diseases of global public health importance. The primary areas of research include vaccines and biologics research for HIV/AIDS, coronaviruses, influenza, malaria, and pandemic preparedness.

Division of Microbiology and Infectious Diseases

Emily Erbelding, M.D., M.P.H.

Emily Erbelding, M.D., M.P.H.
Director, Division of Microbiology and Infectious Diseases

Credit: NIAID

The Division of Microbiology and Infectious Diseases (DMID) supports extramural research to control and prevent diseases caused by virtually all human infectious agents except HIV. DMID provides funding opportunities and a comprehensive set of resources for researchers that support basic research, preclinical development, and clinical evaluation.

Research Focus

DMID conducts and supports research on nearly 300 infectious agents and investigates the biological properties of these pathogens and the immune system’s responses to them. Findings from this research are vital to NIAID efforts to create vaccines, drugs, and diagnostic tools to better diagnose, prevent, and treat infectious diseases.

Read more about the specific diseases and pathogens.

Product Development Support

DMID supports product development research in a variety of ways, including NIAID funding opportunities and solicitations, and services for each stage of the product development pathway. 

Read more about more about support for infectious disease product developers.

Organization

Scientific Success Stories

Read how researchers have used DMID resources to move products through the development pipeline.


Scientific Success Stories

Funding Opportunities

NIAID and NIH offer a number of funding opportunities, including grants and contracts to conduct basic research, preclinical development, or clinical evaluation.

Read the Concepts–Potential Opportunities for potential funding opportunities from DMID.


See all Funding Opportunities

Networks

NIAID partners with leaders in the field of infectious disease research to better understand the diseases and move forward toward better prevention, diagnosis, and treatment.


See NIAID-supported networks related to DMID research

Resources for Researchers

DMID supports a comprehensive set of resources for researchers. Their purpose is to facilitate the preclinical and clinical research needed to translate the ideas generated through basic research into safe and effective drugs, vaccines, and diagnostics to control and prevent infectious diseases.


See all DMID resources

Research Rules & Policies

Policies and procedures are essential to any clinical research enterprise. In this regard, the Division of Microbiology and Infectious Diseases has standardized and harmonized operational procedures across research areas.


See all DMID research rules and policies

Division of AIDS

Dieffenbach, Carl W. (Biography Photo)

Carl W. Dieffenbach, Ph.D.
Director, Division of AIDS

Credit: NIAID

The Division of AIDS (DAIDS) was formed in 1986 to develop and implement the national research agenda to address the HIV/AIDS epidemic. Toward that end, the division supports a global research portfolio to advance biological knowledge of HIV/AIDS, its related co-infections, and co-morbidities. With the ultimate goal of creating an “AIDS-Free Generation,” the division develops and supports the infrastructure and biomedical research needed to:

  1. halt the spread of HIV through the development of an effective vaccine and biomedical prevention strategies that are safe and desirable;
  2. develop novel approaches for the treatment and cure of HIV infection;
  3. treat and/or prevent HIV co-infections and co-morbidities of greatest significance; and
  4. partner with scientific and community stakeholders to efficiently implement effective interventions.

Areas of Research

NIAID-supported investigators are conducting an abundance of research on all areas of HIV infection, including developing and testing preventive HIV vaccines, prevention strategies, and new treatments for HIV infection and AIDS-associated opportunistic infections.

Learn more about NIAID's research on HIV/AIDS.

Refining the HIV Research Enterprise

NIH will refine its science-driven HIV research enterprise to deliver the innovative, efficient results we need to turn the corner on the HIV/AIDS pandemic.


Read more about the HIV Clinical Research Enterprise

Funding Opportunities

NIAID and NIH offer a number of funding opportunities, including grants and contracts, to conduct basic research, preclinical development, or clinical evaluation.

Potential Funding Opportunities:


See all Funding Opportunities related to HIV/AIDS

Networks

NIAID partners with leaders in the field of HIV/AIDS research to better understand the diseases and move forward toward a better prevention, diagnosis, and treatment.


See NIAID-supported networks related to DAIDS research

Resources for Researchers

The Division of AIDS supports a comprehensive set of resources for researchers. Their purpose is to facilitate the preclinical and clinical research needed to translate the ideas generated through basic research into safe and effective drugs, vaccines, and diagnostics to control and prevent the spread of HIV.


See all resources for researchers

Research Rules & Policies

Policies and procedures are essential to any clinical research enterprise. In this regard, the Division of AIDS has standardized and harmonized operational procedures across research areas.


See all DAIDS Research Rules & Policies

Cholera is an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae. An estimated 3-5 million cases and over 100,000 deaths occur each year around the world. The infection is often mild or without symptoms, but can sometimes be severe. Approximately one in 10 (5 to 10 percent) infected persons will have severe disease characterized by profuse watery diarrhea, vomiting, and leg cramps. In these people, rapid loss of body fluids leads to dehydration and shock. Without treatment, death can occur within hours.

Why Is the Study of Cholera a Priority for NIAID?

Because the bacteria that cause cholera, Vibrio cholerae, are spread through contaminated water, cholera is not a public health issue in countries where drinking water and sewage are separated and treated. It is unlikely that a large outbreak of cholera would occur in the United States or other developed countries, but cholera epidemics are a very big public health concern in Haiti, India, and other developing areas of the world.

How Is NIAID Addressing This Critical Topic?

NIAID-supported scientists conducting basic cholera research are studying the evolution and genetics of V. cholerae, and how the micro-organism interacts with environmental factors. Scientists are exploring several approaches to develop improved vaccines for cholera, and are devising new drugs based on small molecules and natural products to treat cholera and other related diarrheal diseases.

Related Public Health and Government Information

To learn about risk factors for Cholera and current prevention and treatment strategies visit the MedlinePlus cholera site.

Image of cholera
Image of Vibrio cholerae

Vibrio cholerae

Credit: CDC
Cholera
Page Summary
Cholera is an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae. An estimated 3-5 million cases and over 100,000 deaths occur each year around the world. The infection is often mild or without symptoms, but can sometimes be severe. Without treatment, death can occur within hours.
Research Area Type
Diseases & Conditions

Pertussis, also known as whooping cough, is a highly contagious respiratory disease. It is caused by the bacterium Bordetella pertussis. Pertussis is known for uncontrollable, violent coughing that often makes it hard to breathe. After fits of many coughs, someone with pertussis often needs to take deep breaths, which result in a “whooping” sound.

Why Is the Study of Pertussis (Whooping Cough) a Priority for NIAID?

Pertussis most commonly affects infants and young children and can be fatal, especially in babies less than 1 year of age. With the resurgence in pertussis in recent years—in 2012, U.S. rates reached a 50-year high of 48,000 reported cases—there remains a strong need for research to support the development of new and effective prevention measures.

How Is NIAID Addressing This Critical Topic?

Over the years, and continuing into today, NIAID has played a key role in developing and implementing the pertussis research agenda, particularly in understanding the infection process and evaluating vaccines and vaccine regimens. 

Related Public Health and Government Information

To learn about risk factors for pertussis or whooping cough and current prevention and treatment strategies visit the Centers for Diseases Control and Prevention (CDC) pertussis (whooping cough) site.

Pertussis (bordetella pertussis) bacteria
Electron microscope image of the bacteria Bordetella pertussis.

Electron microscope image of the bacteria Bordetella pertussis.

Credit: Sanofi Pasteur
pertussis whooping cough
Page Summary
Pertussis, also known as whooping cough, is a highly contagious respiratory disease. It is caused by the bacterium Bordetella pertussis. Pertussis is known for uncontrollable, violent coughing that often makes it hard to breathe. After fits of many coughs, someone with pertussis often needs to take deep breaths, which result in a “whooping” sound.
Research Area Type
Diseases & Conditions

Seasonal influenza, or flu, is a highly contagious respiratory illness caused by influenza viruses that infect the nose, throat and lungs. The two main types of influenza viruses—types A and B—are the viruses that typically spread in people (human influenza viruses) and cause annual flu outbreaks. Each year, influenza causes millions of illnesses worldwide and, in the United States, results in thousands of hospitalizations and deaths. Influenza is especially dangerous for people 65 years and older, young children and people with certain health conditions, such as heart disease or asthma.  

An influenza pandemic occurs when a new influenza virus emerges that is able to infect and spread easily from person to person and to which most of the global population does not have immunity. The last known influenza pandemic occurred in 2009 with the emergence of the H1N1 influenza virus.  Research to find new and improved ways to diagnose, treat and prevent seasonal influenza and novel influenza viruses with pandemic potential is essential to protecting the public health.  

Related Public Health and Government Information

To learn about risk factors for the flu and current prevention and treatment strategies visit the MedlinePlus flu site.

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Volunteer for Clinical Trials

Find out how you can make a difference by participating in clinical research to find new and improved ways to understand, detect, treat and prevent influenza. 

Find featured NIAID influenza studies.

Visit ClinicalTrials.gov for a full list of influenza studies funded by NIH.

Influenza
Page Summary
Each year, influenza causes millions of illnesses worldwide and, in the United States, results in thousands of hospitalizations and deaths. Influenza is especially dangerous for people 65 years and older, young children and people with certain health conditions, such as heart disease or asthma. Research to find new and improved ways to diagnose, treat and prevent seasonal influenza and novel influenza viruses with pandemic potential is essential to protecting the public health. 

Highlights

Research Area Type
Diseases & Conditions