NIAID offers many resources to support your research, including reagents, model organisms, and tissue samples, to name just a few. Use the filters under Filter Search Results to narrow your search, or simply enter specific search terms in the search field.
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The specimen repositories are a collaboration between the ACTG and IMPAACT clinical trial networks to make the large body of specimens collected for HIV research available to investigators.
The specimens stored at the repositories were initially collected for specific studies that have concluded, and are now available to investigators conducting new research.
The aerobiology team develops aerosol animal models of disease caused by high-consequence pathogens. Using advanced inhalational technologies, this team provides high experimental reproducibility to ensure the best modeling possible. Aerosolization procedures are fine-tuned to achieve accurate and precise dosimetry.
Developing, characterizing, and refining animal models rely on sophisticated medical imaging equipment; aerosol capabilities; and virology, pathology, molecular biology, and immunology expertise.
The NIAID-funded Bioinformatics Resource Centers provide data-driven, production-level, sustainable computational platforms to enable sharing and access to data, portable computational tools, and standards that support interoperability for the infectious diseases research community.
NIAID CEIRS provides the BEI Resources Repository with high-priority reagents from the CEIRS community. Reagents include plasmids, antibodies, proteins, and virus isolates. Reagents not available through BEI can be requested on this page. Non-BEI reagents may be available from CEIRS researchers upon request.
The Clinical Studies Support Team (CSST) develops and fosters overseas relationships through continuous support of research studies and clinical trials involving pathogens of high consequence. When deployed, the team provides in-person training and assistance with assays, equipment, and project management.
The core services team provides cell culture, hematology, hemostasis, clinical chemistry, microbiology, and molecular virology support for infectious disease studies at the IRF-Frederick. The team has the ability to perform pre-screening assessment by having parallel setups of clinical analyzers in biosafety level 4 (BSL-4) and BSL-2.
The drug screening team tests and characterizes novel compounds, drugs, and antibodies against numerous viruses in multiple cell lines under a variety of conditions. Compounds are evaluated in cell-based assays for inhibition of viral replication and reduction of virus yields, plaques, or cytopathic effect.
The Early Phase Clinical Trial Units (EPCTUs) support the design, development, implementation, and conduct of Phase 0 to Phase 2 clinical trials, including proof-of-concept studies in healthy, special, and disease-specific populations, carried out in an expeditious and efficient manner, aided by bioanalysis when necessary, against viral, bacterial, parasitic, and fungal pathogens and
The electron microscopy (EM) laboratory team uses transmission electron microscopy (TEM), scanning electron microscopy (SEM), negative staining techniques and assays, immunogold labeling, quantitation of biological samples, and other specialized methods.
The HIV Database and Analysis Unit provides an integrated repository of HIV sequence and immunological data from publications, by (i) curating and maintaining a relational database with searchable web access for the scientific community, and (ii) developing web-based computational analysis tools for researchers.
The Human Tissue and Organ Research Resource (HTORR) provides high-quality human biospecimens to investigators to facilitate scientific advances in biomedical research across multiple disciplines.
The Immcantation framework is developed as a start-to-finish analytical ecosystem for large-scale characterization of B cell receptor (BCR) and T cell receptor (TCR) repertoires from high-throughput adaptive immune receptor repertoire sequencing (AIRR-seq) datasets.
The immunology team interrogates immune responses against pathogens requiring maximum containment by use of a variety of capabilities.
The International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Early Career Investigator Mentored Research program aims to support the development of early career investigators to enter the field of maternal/child HIV research and advance the mission of the IMPAACT Network.
The main purpose of the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Laboratory Center is to support the network’s scientific agenda by providing state of the art laboratory testing in support of clinical trials, new works concept sheets (NWCS), and data analysis concept sheets (DACS); designing and evaluating new assays to elucidate pathogenesis; and providing sci
The In Vitro Assessment for Antimicrobial Activity program provides capability in a broad range of in vitro assessments to evaluate promising candidate countermeasures for antimicrobial activity against microbial pathogens and vectors, including those derived from clinical specimens.
The National Biocontainment Laboratories (NBLs) and Regional Biocontainment Laboratories (RBLs) provide BSL4/3/2 and BSL3/2 biocontainment facilities, respectively, for research on biodefense and emerging infectious disease agents.
The Gnotobiotic Animal Facility houses purchased experimental mice in experimental isolators that serve as important resources for researchers studying the microbiome. The mice in this facility are germ-free, i.e., born and raised in absence of live microbes.
NIAID’s microbiome sequencing facility studies the structure and function of the microbiome associated with various hosts and body sites. This facility has one dedicated team and is equipped with an Ilumina MiSeq, which can sequence whole genomes or specific amplicons.