Jenna R.E. Bergerson, M.D., M.P.H.

Staff Clinician
Associate Program Director, Allergy-Immunology Fellowship Training Program
Co-Director, Allergy-Immunology Consult Service
Deputy Director, Primary Immune Deficiency Clinic

Major Areas of Research

  • Diagnosis, natural history, and treatment of primary immune deficiency disorders and disorders of immune dysregulation


Jenna Bergerson, M.D. is an assistant research physician at NIAID. She has been involved in translational research in primary immune deficiencies and disorders of immune dysregulation since joining the Primary Immune Deficiency Clinic in 2017.

She received her M.D. from Tulane University School of Medicine. She completed a pediatric residency at Rainbow Babies & Children’s Hospital, Case Western University Medical Center in Cleveland, OH, followed by a fellowship in allergy and immunology at The Ann & Robert H. Lurie Children’s Hospital of Chicago, Northwestern University Medical Center. She also holds a master of public health degree from Tulane University School of Public Health. She is board certified in pediatrics and allergy-immunology and is a fellow of the American Academy of Allergy, Asthma, and Immunology (AAAAI) and the Clinical Immunology Society (CIS).

At NIH, she serves as the co-director of the Allergy-Immunology Consult Service, as the Deputy Director of the Primary Immune Deficiency Clinic, and on the NIAID inpatient-outpatient working group committee. Her external committee activities include involvement in the membership committee of the Clinical Immunology Society.

Program Description

Dr. Bergerson’s current research and clinical activities focus on seeing patients with a wide variety of primary immune deficiency disorders and primary disorders of immune dysregulation.

Selected Publications

Hsu AP, Donkó A, Arrington ME, Swamydas M, Fink D, Das A, Escobedo O, Bonagura V, Szabolcs P, Steinberg HN, Bergerson J, Skoskiewicz A, Makhija M, Davis J, Foruraghi L, Palmer C, Fuleihan RL, Church JA, Bhandoola A, Lionakis MS, Campbell S, Leto TL, Kuhns DB, Holland SM. Dominant activating RAC2 mutation with lymphopenia, immunodeficiency, and cytoskeletal defects. Blood. 2019 May 2;133(18):1977-1988.

Bergerson JRE, Freeman AF. An Update on Syndromes with a Hyper-IgE Phenotype. Immunol Allergy Clin North Am. 2019 Feb;39(1):49-61. doi: 10.1016/j.iac.2018.08.007. Review. PMID:30466772

Arts K, Bergerson JRE, Ombrello AK, Similuk M, Oler AJ, Agharahimi A, Mace EM, Hershfield M, Wouters C, De Somer L, Morren MA, Diego RP, Moens L, Freeman AF, Meyts I. Warts and DADA2: a Mere Coincidence? J Clin Immunol. 2018 Nov;38(8):836-843.

Jhamnani RD, Nunes-Santos CJ, Bergerson J, Rosenzweig SD. Class-Switch Recombination (CSR)/Hyper-IgM (HIGM) Syndromes and Phosphoinositide 3-Kinase (PI3K) Defects. Front Immunol. 2018 Sep 26;9:2172.

Gupta M, Aluri J, Desai M, Lokeshwar M, Taur P, Lenardo M, Bergerson J, Dalvi A, Mhatre S, Kulkarni M, Kambli P, Madkaikar M. Clinical, Immunological, and Molecular Findings in Four Cases of B Cell Expansion With NF-κB and T Cell Anergy Disease for the First Time From India. Front Immunol. 2018 Jun 14;9:1049.

Khanolkar A, Kirschmann DA, Caparelli EA, Wilks JD, Cerullo JM, Bergerson JRE, Jennings LJ, Fuleihan RL. CD4 T cell-restricted IL-2 signaling defect in a patient with a novel IFNGR1 deficiency. J Allergy Clin Immunol. 2018 Jan;141(1):435-439.e7.

Visit PubMed for a complete publication listing.

Training Program

Allergy and Immunology

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