Michael P. Fay, Ph.D.

Mathematical Statistician, Biostatistics Research Branch

Michael P. Fay, Ph.D. Mathematical Statistician, Biostatistics Research Branch, DCR, NIAID, NIH


Measures of Agreement, Interval Censored Data, Permutation Tests, Malaria Vaccine Development

Additional Information

Curriculum Vitae

Selected Publications

Fay, MP, Brittain, EH, Proschan, MA (2013). Pointwise confidence intervals for a survival distribution with small samples or heavy censoring. Biostatistics 2013; doi: 10.1093/biostatistics/kxt016

Fay MP, Follmann DA, Lynn F, Schiffer JM, Stark GV, Kohberger R, Quinn CP, Nuzum EO. (2012). Anthrax Vaccine Induced Antibodies Provide Cross-Species Prediction of Survival to Aerosol Challenge. Science Translational Medicine 4: 151ra126.

Fay MP, Shih JH. (2012). Weighted Logrank Tests for Interval Censored Data when Assessment Times Depend on Treatment. Statistics in Medicine. doi: 10.1002/sim.5447.

"All Michael Fay publications"


Fay, M.P., Halloran, M.E., Follmann, D.A., Diemert, D., Dicko, A., Thera, M., Sagara, I., Klion, A., Doumbo, O., Saul, A. (2005). The Design of a Phase 2 Malaria Vaccine Trial Based on a Cohort Study. Poster presented at 4th MIM Pan-African Malaria Conference.

Fay, M.P., Huang, C-Y., Twum-Danso, N.A.Y. (2007). Monitoring Rare Serious Adverse Events from a New Treatment and Testing for Difference from a Baseline Rate. (PDF) Poster presented at 2007 EMR-IBS conference, Eilat, Israel.

Recent Work

Follmann DA, Fay MP, Proschan MA. (2007). Chop-lump Tests for Vaccine Trials (unpublished manuscript).

Fay MP, Kim H-J, Hachey M. (2007). On using Truncated Sequential Probability Ratio Test Boundaries for Monte Carlo Implementation of Hypothesis Tests.  (to appear in Journal of Computational and Graphical Statistics).

Software Written by Michael Fay

The exact2x2 R package that gives matching confidence intervals for Fisher’s exact test and Blaker’s exact test as described in Fay (2009).

hbim R package to perform calculations related to the Hill/Bliss independence model as applied to mulitcomponent vaccines as described by Saul and Fay (2007).

Note this package is the exactly the same as the one on the PLoS ONE site, except the reference has been updated, and the date on the vignette (calculation details document) was changed when it was rebuilt.


choplump R package to perform permutation tests when there are a high proportion of zeros for responses as described in Follmann, Fay, and Proschan (2007).

Interval Censored Data Functions (S-PLUS functions)

Small Sample Adjustments for Wald-type Tests using Sandwich Estimators (S-Plus functions)

MChtest R package to perform Monte Carlo hypothesis testing with sequential stopping as described in Fay, Kim, and Hachey (2007)

ssanv R package to calculate sample sizes that account for variability as described in Fay, Halloran, Follmann. (2007)

Software Developed With Collaborators

Conditional Logistic Regression with Sandwich Estimators (PC executable files with Fortran code)

Joinpoint Regression (PC executable with GUI)

Probability of Developing or Dying of Cancer (PC executable with GUI)

Content last reviewed on May 9, 2017