Bruce Swihart, Ph.D.

Mathematical Statistician, Biostatistics Research Branch

Bruce Swihart, Ph.D. Mathematical Statistician, Biostatistics Research Branch, DCR, NIAID, NIH

Bruce Swihart, Ph.D. 

Credit: NIAID


Dr. Bruce Swihart joined the Biostatistics Research Branch (BRB) in 2014. He primarily works with collaborators studying Malaria, serving as a mathematical statistician. His academic degrees are from the University of Colorado and Johns Hopkins Bloomberg School of Public Health. His interests include correlated binary data and stable distributions. He is an active maintainer and developer of R-packages for CRAN.



Bruce J Swihart, Michael P Fay, and Kazutoyo Miura. Statistical methods for standard membrane-feeding assays to measure transmission blocking or reducing activity in malaria. Journal of the American Statistical Association, 113(522):534–545, 2018.

Bruce J Swihart, Naresh M Punjabi, and Ciprian M Crainiceanu. Modeling sleep fragmentation in sleep hypnograms: An instance of fast, scalable discrete-state, discrete-time analyses. Computational Statistics & Data Analysis, 89:1–11, 2015.

Ciprian Crainiceanu, Philip Reiss, Jeff Goldsmith, Lei Huang, Lan Huo, Fabian Scheipl, Bruce Swihart, and Maintainer Lei Huang. Package ‘refund’. 2014.

Bruce J Swihart, Brian S Caffo, and Ciprian M Crainiceanu. A unifying framework for marginalised random-intercept models of correlated binary outcomes. International Statistical Review, 82(2):275–295, 2014.

Bruce J Swihart, Jeff Goldsmith, and Ciprian M Crainiceanu. Restricted likelihood ratio tests for functional effects in the functional linear model. Technometrics, 56(4):483–493, 2014.

Michael E Griswold, Bruce J Swihart, Brian S Caffo, and Scott L Zeger. Practical marginalized multilevel models. Stat, 2(1):129–142, 2013.

Roland Langrock, Bruce J Swihart, Brian S Caffo, Naresh M Punjabi, and Ciprian M Crainiceanu. Combining hidden markov models for comparing the dynamics of multiple sleep electroencephalograms. Statistics in medicine, 32(19):3342–3356, 2013.

Bruce J Swihart, Brian S Caffo, Ciprian M Crainiceanu, and Naresh M Punjabi. Mixed effect poisson log-linear models for clinical and epidemiological sleep hypnogram data. Statistics in medicine, 31(9):855–870, 2012.

Bruce J Swihart. From Individuals to Populations: Application and Insights Concerning the Generalized Linear Mixed Model. PhD thesis, THE JOHNS HOPKINS UNIVERSITY, 2011.

Matthew Strand, Yu Zhang, and Bruce J Swihart. Monotone nonparametric regression and confidence intervals. Communications in Statistics-Simulation and Computation ® , 39(4):828–845, 2010.


Michal Fried, Jonathan D Kurtis, Bruce Swihart, Robert Morrison, Sunthorn Pond-Tor, Amadou Barry, Youssoufa Sidibe, Sekouba Keita, Almahamoudou Mahamar, Naissem Andemel, and others. Antibody levels to recombinant var2csa domains vary with plasmodium falciparum parasitaemia, gestational age, and gravidity, but do not predict pregnancy outcomes. Malaria journal, 17(1):106, 2018.

Rajeev Gautam, Yoshiaki Nishimura, Natalie Gaughan, Anna Gazumyan, Till Schoofs, Alicia Buckler-White, Michael S Seaman, Bruce J Swihart, Dean A Follmann, Michel C Nussenzweig, and others. A single injection of crystallizable fragment domain–modified antibodies elicits durable protection from shiv infection. Nature medicine, 24(5):610, 2018.

Michal Fried, Jonathan D Kurtis, Bruce Swihart, Sunthorn Pond-Tor, Amadou Barry, Youssoufa Sidibe, Santara Gaoussou, Moussa Traore, Sekouba Keita, Almahamoudou Mahamar, and others. Systemic inflammatory response to malaria during pregnancy is associated with pregnancy loss and preterm delivery. Clinical Infectious Diseases, 65(10):1729–1735, 2017.

Almahamoudou Mahamar, Oumar Attaher, Bruce Swihart, Amadou Barry, Bacary S Diarra, Moussa B Kanoute, Kadidia B Cisse, Adama B Dembele, Sekouba Keita, Benoît Gamain, and others. Host factors that modify plasmodium falciparum adhesion to endothelial receptors. Scientific Reports, 7(1):13872, 2017.

Sameer S Kadri, Bruce J Swihart, Stephanie L Bonne, Samuel F Hohmann, Laura V Hennessy, Peter Louras, Heather L Evans, Chanu Rhee, Anthony F Suffredini, David C Hooper, and others. Impact of intravenous immunoglobulin on survival in necrotizing fasciitis with vasopressordependent shock: A propensity score–matched analysis from 130 us hospitals. Clinical Infectious Diseases, 64(7):877–885, 2016.

Kazutoyo Miura, Bruce J Swihart, Bingbing Deng, Luwen Zhou, Thao P Pham, Ababacar Diouf, Timothy Burton, Michael P Fay, and Carole A Long. Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in plasmodium falciparum standard membrane-feeding assay. Vaccine, 34(35):4145–4151, 2016.

Hongyuan Gao, Diana SM Buist, Timothy L Lash, Jaclyn LF Bosco, and Bruce Swihart. Lasagna plots made in different (statistical) ovens. Epidemiology, 23(6):934, 2012.

Alison Laffan, Brian Caffo, Bruce J Swihart, and Naresh M Punjabi. Utility of sleep stage transitions in assessing sleep continuity. Sleep, 33(12):1681, 2010.

David Patz, Mark Spoon, Richard Corbin, Michael Patz, Bruce Swihart, Louise Dover, and David White. The importance of evaluating obstructive sleep apnea patients at their home altitude. SALUD I CIENCIA, 17(5):435–439, 2010.

David Patz, Mark Spoon, Richard Corbin, Michael Patz, Bruce Swihart, Louise Dover, and David White. La apnea obstructiva del sueño debe evaluarse en la altitud en que viven los pacientes. Salud (i) cienc.,(Impresa), 17(5):435–439, 2010.

David S Patz, Bruce Swihart, and David P White. Cpap pressure requirements for obstructive sleep apnea patients at varying altitudes. Sleep, 33(5):715, 2010.

Bruce J Swihart, Brian Caffo, Bryan D James, Matthew Strand, Brian S Schwartz, and Naresh M Punjabi. Lasagna plots: A saucy alternative to spaghetti plots. Epidemiology, 21(5):621–625, 2010.

Brian Caffo, Bruce Swihart, Ciprian Crainiceanu, Alison Laffan, and Naresh Punjabi. An overview of observational sleep research with application to sleep stage transitioning. Chance, 22(1):10–15, 2009.

Sommer E Gentry, Robert A Montgomery, Bruce J Swihart, and Dorry L Segev. The roles of dominos and nonsimultaneous chains in kidney paired donation. American Journal of Transplantation, 9(6):1330–1336, 2009.

Bruce J Swihart, Brian Caffo, Karen Bandeen-Roche, and Naresh M Punjabi. Characterizing sleep structure using the hypnogram. Journal of clinical sleep medicine: JCSM: official publication of the American Academy of Sleep Medicine, 4(4):349, 2008.

David Patz, Mark Spoon, Richard Corbin, Michael Patz, Louise Dover, Bruce Swihart, and David White. The effect of altitude descent on obstructive sleep apnea. CHEST Journal, 130(6):1744–1750, 2006.

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